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Found 1280 clinical trials
Investigations of Juvenile Neuronal Ceroid Lipofuscinosis

Background CLN3, or Batten disease, is a genetic disorder. This deadly disease leads to decline of brain and nervous system functions. Symptoms of CLN3 typically occur between 4 and 7 years of age. They include changes in how a person sees, thinks, and moves. CLN3 can also cause seizures. No …

genetic disorder
seizure
ceroid lipofuscinosis
batten
  • 93 views
  • 16 Jun, 2021
  • 1 location
Acute and Chronic Toxicity of Some Synthetic Cannabinoids in Assiut Psychiatric Hospitals

Synthetic cannabinoids (SCs) are new human-made mind-altering chemicals which are similar to chemicals found in the marijuana plant; they are recent to be used recreationally, especially by young adults. This new generation of novel cannabinoid compounds have been developed to avoid drug control laws and routine cannabinoid blood tests

  • 0 views
  • 03 Feb, 2021
  • 1 location
Cognition and Psychotherapy in PTSD

Posttraumatic stress disorder (PTSD) is prevalent among combat Veterans and is a substantial public health burden. Several psychotherapies, including cognitive processing therapy (CPT) and prolonged exposure therapy, have been recommended as efficacious for the treatment of PTSD and are being disseminated nationally in the VA Healthcare System. Yet many individuals …

exposure therapy
psychotherapy
  • 92 views
  • 01 Apr, 2021
  • 1 location
Optimising the Care and Treatment Pathways for Older Patients Facing Major Gastrointestinal Surgery.

The UK population is ageing. Whilst many people remain active and in good health as they get older, getting older is associated with the onset of many common medical conditions, as well as memory and mobility problems. There is a natural decline in heart and lung fitness with age, although …

  • 0 views
  • 28 Jan, 2021
  • 2 locations
Temporal Disorders in Left and Right Brain-Damaged Patients

Time is an important function that permeates our everyday activities but it has been so far significantly under-investigated in neurological patients. For instance, it is known that right brain damaged (RBD) patients with spatial attentional deficit (neglect) are impaired in both the ability to estimate the duration of an event …

  • 0 views
  • 25 Jan, 2021
  • 1 location
Validation of an Ecological Organization and Problem Solving Test (TEM-PRO) in Vocational Rehabilitation

Standard neuropsychological evaluations after severe TBI (traumatic brain injury) often minimizes the executive deficits, these latter are known to seriously impair return to work. Therefore, we developed an ecological organization and problem-solving test in a vocational setting called the TEM-PRO. The test consists of 4 activities of variable complexity, collection …

stroke
traumatic brain injury
  • 0 views
  • 25 Jan, 2021
  • 1 location
Personalizing Mediterranean Diet in Children.

Investigating glucose response to Mediterranean and regular diets in healthy children in order to develop specific pediatric machine-learning for predicting the personalized glucose response to food for individual children. The prediction will be based on multiple measurements, including blood tests, personal lifestyle and gut microbiome. This will allow investigators to …

mediterranean diet
  • 0 views
  • 25 Jan, 2021
  • 1 location
Natural History Study of Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation (LBSL)

In this study, we will conduct retrospective chart and imaging reviews and prospective longitudinal virtual assessments of individuals with LBSL.

genetic analysis
  • 13 views
  • 25 Jan, 2021
  • 1 location
Neuroinflammation in Chronic Systemic Symptoms (CSS)

The purpose of the present research protocol is to investigate and identify translocator protein 18kDa, MRI DTI, and EEG/ERPs, markers of Chronic Systemic Symptoms (CSS).

  • 0 views
  • 27 Jan, 2021
  • 1 location
Renal Oxygen Saturation During Off-pump Coronary Artery Bypass Graft Surgery

The purpose of this study is to evaluate changes in renal oxygen saturation (rrSO2) and its relationship with central venous oxygen saturation (cvSO2), cerebral cortical oxygen saturation (rcSO2), and hemodynamic parameters while displacing the heart for each coronary anastomosis in 19-80 year old adult patients receiving off-pump coronary artery bypass …

  • 0 views
  • 26 Jan, 2021
  • 1 location