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Found 10 clinical trials
Influence of a Dietary Supplement as Treatment of Migraine in Children and Adolescents

Migraine in children and adolescents can be associated with low serum levels of coenzyme q10, the key-enzyme of mitochondrial energy production.During migraine attacks inflammation is an

migraine in children
coenzyme q10
  • 08 Nov, 2020
  • 2 locations
Valproic Acid and Dihydroergotamine as Abortive Therapy in Pediatric Migraine

The objective of this study is to compare clinical efficacy and tolerability of valproic acid (VPA) therapy versus dihydroergotamine (DHE) as abortive therapy in pediatric migraine.

  • 30 Mar, 2020
  • 1 location
A Study to Test if Fremanezumab is Effective in Preventing Migraine in Children and Adolescents

The primary objective of the study is to evaluate the long-term safety and tolerability of subcutaneous fremanezumab in the preventive treatment of migraine in pediatric participants 6 to 17 years of age (inclusive at enrollment in the pivotal study). Secondary objectives are to evaluate the efficacy of subcutaneous fremanezumab in …

  • 30 Dec, 2020
  • 11 locations
A 12-Month Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

The reason for this 12-month, open-label study is to see if the study drug lasmiditan is safe and effective for the intermittent acute treatment of migraine in children aged 6 to 17. The study

migraine in children
acute treatment
  • 16 Jan, 2021
  • 220 locations
CHOCOlate MeLatonin for AdolescenT MigrainE

Existing treatments for acute migraine are not effective for all children and adolescents, and can cause side effects. We propose a dose-finding study of melatonin for acute migraine treatment in children and adolescents to determine the best dose to bring forward in a future fully-powered efficacy trial.

migraine in children
acute migraine
acute treatment
episodic migraine
  • 08 Nov, 2020
  • 1 location
Intranasal Ketorolac Versus Intravenous Ketorolac for Treatment of Migraine Headaches in Children

ketorolac, IN ketorolac may be a viable and painless alternative to effectively treat acute migraine headaches in children. Therefore, our primary aim is to demonstrate that IN ketorolac is non

acute migraine
  • 19 Oct, 2020
  • 1 location
Transnasal Sphenopalatine Ganglia Block for Management of Chronic Migraines in Pediatric Patients

Single-center, open-label, pre-post treatment pilot study to evaluate the safety and effectiveness of sphenopalatine ganglia blocks for the treatment of chronic migraine in the pediatric population. 50 children with a diagnosis of chronic migraines will undergo a series of three transnasal sphenopalatine ganglia blocks to measure their effect on headache …

  • 21 Dec, 2020
  • 1 location
SPG Block for Acute Pediatric Migraine

This is a randomized double blind trial comparing an intranasal sphenopalatine block with 2% lidocaine to intravenous (0.15 mg/kg, max 10mg) prochlorperazine in patients greater than 10 years of age presenting to a pediatric emergency department with an acute frontal migraine headache.

  • 16 Jun, 2019
  • 1 location
A Study in Children and Young People With Migraine to Learn What the Body Does to Eptinezumab

The purpose of the study is to investigate how the body absorbs, distributes, and get rid of eptinezumab when given directly into a vein.

  • 15 Jan, 2021
  • 7 locations
Mind and Body Approaches to Pain Reduction in Youth With Migraine

The overarching objective of this protocol is to identify and understand the neural and pain processing mechanisms by which youth with migraine improve in response to preventive treatment. The study design of this mechanistic investigation includes functional magnetic resonance imaging (fMRI), daily headache diaries, assessment of conditioned pain modulation via …

headache disorder
cognitive therapy
behavioral therapy
daily headache
chronic migraine
  • 01 Mar, 2020
  • 1 location