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Found 661 clinical trials
Featured trial
VastBiome: The Gut Microbiome and Immune Checkpoint Inhibitor Therapy in Solid Tumors

are needed to understand how microbiota and their byproducts affect cancer therapies, particularly among patients undergoing identical therapy but experiencing different outcomes. The proposed

programmed cell death 1 ligand 1
cancer chemotherapy
targeted therapy
  • 28 Feb, 2022
  • 1 location
Impact of Sweeteners on Behaviour Physiology & Health

This study aims to evaluate the acute (1-day) and repeated (2-week) effects of combinations of Sweeteners & Sweetness Enhancer blends on metabolic, sensory, neuro-behavioural and microbiota

Accepts healthy volunteers
  • 24 Nov, 2021
  • 5 locations
A Comparison of Four Different Treatment Regimens of Helicobacter Pylori in Chinese Children

children and investigation of resistance, impact factors and changes of microbiota after the therapy. The results of the study will provide theoretical basis to make the new guideline of diagnosis and

  • 25 Mar, 2022
  • 1 location
Creation of a Prospective Cohort of Healthy and Sick Subjects and of a Collection of Associated Biological Resources, for the Study of the Immune System and of Its Genetic and Environmental Determinants. (CoSImmGEn)

CoSImmGEn is a protocol set up to respond to the current lack of healthy and sick population cohorts. Biological resources from these cohorts allow researchers to study the immune system and its genetic and environmental determinants. Those cohorts and collections are open not only to the Pasteurian community but also …

Accepts healthy volunteers
  • 04 Feb, 2022
  • 3 locations
Microbiome Test for the Detection of Colorectal Polyps

The main goal of this trial is to validate a new method for colorectal polyp screening based on stool microbiome signatures. 600 Individuals who are scheduled / planned to undergo a colonoscopy will be recruited for this study and a stool sample and an optional saliva sample will be collected. …

colorectal polyps
  • 06 Oct, 2021
  • 2 locations
Vaginal Microbiota Transplant (MOTIF)

This is a randomized trial of vaginal microbiome transplant vs. saline placebo to restore a Lactobacillus dominant vaginal microbial community in women with recurrent bacterial vaginosis.

  • 28 Feb, 2022
Probiotic Modulation of Oral Microbiota (PROROBIOTICS)

Targeting human microbiota, in particular those of the gastrointestinal tract, by means of prebiotics, probiotics, symbiotics or antibiotics has gained interest for its potential in the

Accepts healthy volunteers
  • 09 Apr, 2022
Fecal Microbiota Transplantation for Pouchitis

fecal microbiota transplantation once weekly for six weeks increases the remission rate compared to placebo in patients with active pouchitis.

  • 23 Apr, 2022
  • 1 location
Microbiota and Bone Fragility:Study of the Relation Between Gut Microbiota and Bone Microarchitecture (MICROBONE)

Gut microbiota regulate metabolism of their human host. Some diseases are associated with variations in gut microbiota diversity and higher fracture risk. Intestinal bacteria synthesize or

bone mineral density
quantitative computed tomography
spinal fracture
bone densitometry
postmenopausal osteoporosis
  • 26 Feb, 2022
  • 1 location
Fecal Microbiota Transplantation for C Diff Infection

The objective of this study is to provide treatment with Fecal Microbiota Transplantation (FMT) to patients with recurrent or refractory Clostridium difficile infection (CDI). It has been shown

clostridium difficile
fecal microbiota transplantation
  • 26 Aug, 2021
  • 1 location