Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 29 clinical trials
None
Observation Combination Chemotherapy Radiation Therapy and/or Autologous Stem Cell Transplant in Treating Young Patients With Neuroblastoma

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving combination chemotherapy may kill more tumor cells. Radiation therapy uses high-energy x-rays to kill tumor cells. An autologous stem cell transplant may …

cyclophosphamide
melphalan
combination chemotherapy
vindesine
filgrastim
  • 30 views
  • 07 Nov, 2020
  • 28 locations
None
MIBG Therapy for Patients With MIBG Avid Tumors

This is a Phase II study for patients with MIBG avid tumors. The study is to determine the response rate to <131>I-MIBG in patients with de novo, relapsed or refractory neuroblastoma or

  • 2 views
  • 03 Jun, 2021
  • 1 location
None
131I-MIBG With Myeloablative Chemotherapy and Autologous Stem Cell Transplantation for the Treatment of High-risk Neuroblastoma

This trial is studying how well iodine I 131 metaiodobenzylguanidine together with combination chemotherapy works in treating patients who are undergoing an autologous peripheral stem cell for high risk or relapsed neuroblastoma.

high-risk neuroblastoma
melphalan
combination chemotherapy
etoposide
iobenguane
  • 8 views
  • 07 Nov, 2020
  • 2 locations
None
Evaluation of 2 Intensification Treatment Strategies for Neuroblastoma Patients With a Poor Response to Induction

The main objective is to evaluate the efficacy of two intensified consolidation strategies in very-high risk neuroblastoma (VHR-NBL) patients in terms of event-free survival from randomisation date. This evaluation will follow a hierarchical testing procedure: each experimental treatment will be first evaluated as a single-arm phase 2 study, and in …

  • 1 views
  • 11 Jun, 2021
  • 2 locations
None
Assessment of 18F-Florbetaben Whole-body PET for the Detection of Cardiac and Extracardiac Sites of Amyloid Deposits

Although being classified as a rare disease, cardiac amyloidosis constitutes an increasing cause of heart failure, which is often overlooked and thus poorly managed. Amyloidosis involves deposits of light chain immunoglobulins in the immunoglobulin light chain amyloidosis (AL) type, but it may also be of a hereditary type in mutated …

  • 0 views
  • 20 Aug, 2021
  • 1 location
None
Diagnosis of Pheochromocytoma

carried out. Standard imaging tests - Non-investigational imaging tests include computed tomography (CT), magnetic resonance imaging (MRI), sonography, and 123I-MIBG scintigraphy and FDG

clonidine
positron emission tomography
dopamine
metastatic disease
computed tomography
  • 20 views
  • 05 Sep, 2021
  • 2 locations
None
Iobenguane I-131 or Crizotinib and Standard Therapy in Treating Younger Patients With Newly-Diagnosed High-Risk Neuroblastoma or Ganglioneuroblastoma

This phase III trial studies iobenguane I-131 or crizotinib and standard therapy in treating younger patients with newly-diagnosed high-risk neuroblastoma or ganglioneuroblastoma. Radioactive drugs, such as iobenguane I-131, may carry radiation directly to tumor cells and not harm normal cells. Crizotinib may stop the growth of tumor cells by blocking …

high-risk neuroblastoma
cyclophosphamide
mycn protein
melphalan
stem cell transplantation
  • 66 views
  • 03 Sep, 2021
  • 105 locations
None
MIBG With Dinutuximab +/- Vorinostat

131I-Metaiodobenzylguanidine (131I-MIBG) is one of the most effective therapies utilized for neuroblastoma patients with refractory or relapsed disease. In this pediatric phase 1 trial, 131I

monoclonal antibodies
vorinostat
cancer
avid
monoclonal antibody ch14.18
  • 38 views
  • 29 Jan, 2021
  • 11 locations
None
MIBG for Refractory Neuroblastoma and Pheochromocytoma

This is a best available therapy/compassionate use single institution study designed to determine the palliative benefit and toxicity of 131I-MIBG in patients with progressive neuroblastoma and

gm-csf
catecholamines
monoclonal antibodies
myelosuppressive chemotherapy
total body irradiation
  • 5 views
  • 29 Jan, 2021
  • 1 location
None
Study of MIBG-I131 in Patients With Well Differentiated Neuroendocrine Tumors

This is a single-arm, unicentric, single-stage, phase 2 clinical study of therapeutic metaiodobenzylguanidine (MIBG) for patients with metastatic well-differentiated neuroendocrine tumors and

  • 0 views
  • 13 Apr, 2021
  • 1 location