methotrexate Clinical Research Trials

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Found 285 clinical trials

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Have you been diagnosed with rheumatoid arthritis?

methotrexate. This research study will develop a scale measuring intolerance to methotrexate.

63 views
23 Nov, 2020
1 location

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A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Efficacy and Safety Study of Methotrexate to Increase Response Rates in Patients with Uncontrolled Gout Receiving KRYSTEXXA® (pegloticase) (MIRROR Randomized Controlled Trial [RCT])

The purpose of this study is to obtain information on the safety, tolerability and effectiveness of administering an immunosuppressive therapy (Methotrexate) (MTX) in combination with KRYSTEXXA

22 views
23 Nov, 2020
1 location

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A Phase III Double-Blind Trial for Surgically Resected Early Stage Non-Small Cell Lung Cancer: Crizotinib versus Placebo for Patients with Tumors Harboring the Anaplastic Lymphoma Kinase (ALK) Fusion Protein

A Phase III Double-Blind Trial for Surgically Resected Early Stage Non-Small Cell Lung Cancer: Crizotinib versus Placebo for Patients with Tumors Harboring the Anaplastic Lymphoma Kinase (ALK) Fusion Protein

lung cancer

crizotinib

lung carcinoma

98 views
23 Nov, 2020
1 location

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A 52-week, phase 3, multicentre, randomised, double blind, efficacy and safety study comparing GSK3196165 with placebo and with tofacitinib, in combination with MTX in participants with moderately to severely active RA who have an inadequate response to MTX.

A 52-week, phase 3, multicentre, randomised, double blind, efficacy and safety study comparing GSK3196165 with placebo and with tofacitinib, in combination with MTX in participants with moderately to severely active RA who have an inadequate response to MTX.

tofacitinib

55 views
23 Nov, 2020
1 location

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A Double-Blind, Randomized controlled study of Etanercept and Methotrexate in combination or as Monotherapy in subjects with Psoriatic Arthritis

396 views
23 Nov, 2020
1 location

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ACNS0334: A Phase III Randomized Trial for the Treatment of Newly Diagnosed Supratentorial PNET and High Risk Medulloblastoma in Children < 36 months old with Intensive Induction Chemotherapy with Methotrexate Followed by Consolidation with Stem Cell Rescue Versus the Same Therapy Without Methotrexate

with Methotrexate Followed by Consolidation with Stem Cell Rescue Versus the Same Therapy Without Methotrexate

320 views
08 Nov, 2020
1 location

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FINCH 1: A Randomized, Double-blind, Placebo- and Active-controlled, Multicenter, Phase 3 Study to Assess the Efficacy and Safety of Filgotinib Administered for 52 weeks in Combination with Methotrexate to Subjects with Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate

Methotrexate to Subjects with Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate

818 views
23 Nov, 2020
1 location

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GOG 0275: A Phase III Randomized Trial of Pulse Actinomycin-D Versus Multi-Day Methotrexate for the Treatment of Low-Risk Gestational Trophoblastic Neoplasia

174 views
08 Nov, 2020
1 location

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Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused with a Reduced Dose of Non-Mobilized Donor T-Cells

, participants will have regular doses of cyclosporine and methotrexate to prevent rejection of the donor cells. Participants will have three doses of methotrexate within the week after the transplant, but will

myelodysplastic syndrome (mds)

anemia studies

anemia

aplastic anemia

myelodysplastic syndromes

86 views
22 Dec, 2020
1 location

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Comparison of CHS-0214 to Enbrel (Etanercept) in Patients With Rheumatoid Arthritis (RA) (CHS-0214-02)

244 views
08 Nov, 2020
1 location

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Found 285 clinical trials