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Found 26 clinical trials
Non-inferiority Trial Comparing Cloxacillin vs Cefazolin in Methicillin-susceptible Staphylococcus Aureus Bacteremia (CLOCEBA)

"Methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia remains a major cause of community- or hospital-acquired bloodstream infections with an overall mortality estimated around 25

  • 9 views
  • 27 Feb, 2022
  • 1 location
Study to Assess Safety, Tolerability and Efficacy of Afabicin in The Treatment of Participants With Bone or Joint Infection Due to Staphylococcus

methicillin-susceptible S. aureus (MSSA) and methicillin-resistant S. aureus (MRSA)] and/or coagulase-negative staphylococci (CoNS) and to compare it to standard of care (SOC).

  • 11 views
  • 12 May, 2022
  • 4 locations
A Phase 2a Study, Effect of Vancomycin With vs Without Delpazolid (LCB01-0371) in Patients With MRSA Bacteremia

The objectives of this study is to exploratory whether vancomycin + delpazolid is more effective to the standard of treatment (vancomycin)/ for hospitalised adults with MRSA bacteraemia.

  • 0 views
  • 10 May, 2022
  • 1 location
Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections in Children, Known or Suspected to be Caused by Susceptible Gram-positive Organisms, Including MRSA

suspected to be caused by susceptible Gram-positive organisms, including methicillin-resistant strains of Staphylococcus aureus.

MRSA
erosion
surgical incision
leukopenia
staphylococcus aureus
  • 18 views
  • 15 May, 2022
  • 14 locations
Study to Optimize the Use of New Antibiotics (NEW_SAFE)

carbapenem-resistant Acinetobacter baumannii and Pseudomonas aeruginosa, carbapenem-resistant enterobacteria, vancomycin-resistant Enterococcus faecium and methicillin-resistant Staphylococcus aureus

carbapenem
ceftazidime
isavuconazole
staphylococcus
ceftazidime-avibactam
  • 3 views
  • 16 Feb, 2022
  • 13 locations
Antibiotic Prophylaxis in High-Risk Arthroplasty Patients

To determine the effectiveness of a 7-day course of an oral, prophylactic antibiotic on the incidence of periprosthetic joint infection and wound complications following primary total hip and knee arthroplasty in a high-risk patient population.

Accepts healthy volunteers
diabetes
antibiotics
body mass index
  • 5 views
  • 24 Mar, 2022
  • 1 location
Infectious Diseases in Aged Population (AEQUI)

The increasing number of persons >65 years of age form a special population at risk for nosocomial and other health care-associated infections. The vulnerability of this age group is related to impaired host defenses such as diminished cell-mediated immunity. Lifestyle considerations, e.g., travel and living arrangements, and residence in nursing …

blood culture
bacteremia
fever
  • 0 views
  • 24 Mar, 2022
  • 8 locations
Optimal Treatment of MRSA Throat Carriers

The aim of this study is to investigate the optimal way to treat MRSA throat carriers.

decolonization
clindamycin
  • 0 views
  • 25 Mar, 2022
  • 1 location
STaph Aureus Resistance-Treat Early and Repeat (STAR-TER) (STAR-TER)

To evaluate the micro-biologic efficacy and safety of a streamlined treatment for early onset methicillin-resistant staphylococcus aureus (MRSA) in patients with cystic fibrosis.

methicillin
fibrosis
nasal potential difference
pilocarpine
sweat test
  • 66 views
  • 02 Mar, 2022
  • 8 locations
Short and Long Term Outcomes of Doxycycline Versus Trimethoprim-Sulfamethoxazole for Skin and Soft Tissue Infections Treatment

The purpose of this study is to compare how well two different antibiotics, doxycycline (DOXY) and trimethoprim/sulfamethoxazole (TMP/SMX), work at curing uncomplicated skin and soft tissue infection (uSSTI) such as 1.Boils (pus in the skin, also known as abscesses and furuncles) or 2. Infections that appear only on the skin …

  • 0 views
  • 12 Jul, 2021
  • 3 locations