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Found 67 clinical trials
Trial to Shorten Pharmacologic Treatment of Newborns With Neonatal Opioid Withdrawal Syndrome (NOWS)

of weaning to cessation of opioid among infants receiving an opioid (defined as morphine or methadone) as the primary treatment for neonatal opioid withdrawal syndrome (NOWS).

  • 09 Jul, 2022
  • 18 locations
Smartphones for Opiate Addiction Recovery (SOAR)

Treatments for opioid addiction exist, but effectiveness is compromised when subjects use illicit opiates during treatment. Reuse rates during treatment can be high, and reducing illicit opiate use during treatment has thus recently become a major NIDA policy goal. The 5-minute battery indicates the numerical probability that a patient will …

  • 20 Jun, 2022
  • 1 location
Kentucky Women's Justice Community Opioid Innovation Network (W-JCOIN)

This trial will test the effectiveness of delivering medication for opioid use disorder (MOUD) pre-treatment via telehealth, alone and with peer navigation, to increase MOUD initiation and maintenance in the community following jail release. This trial will focus on incarcerated women in 6 experimental and 3 control sites in Kentucky. …

Accepts healthy volunteers
  • 04 Oct, 2022
  • 8 locations
Transcranial Magnetic Stimulation for Methadone Maintenance Therapy Combined With Methamphetamine Abuse

Repetitive transcranial magnetic stimulation (rTMS) has been used to treat opioid and methamphetamine addiction in previous studies, while no evidence was proved for patients methadone

  • 26 Sep, 2021
  • 1 location
Study of LYN-014 in Individuals With Opioid Use Disorder Who Are Stable on Methadone Therapy

A Phase 1, Single Dose, Open-label, Safety, Tolerability, and Pharmacokinetic Study of LYN-014 in Individuals with Opioid Use Disorder Who are Stable on Methadone Therapy

  • 07 Oct, 2022
  • 1 location
Understanding How Methadone Treatment During Surgery Affects Pain Levels and the Need for Pain Medications After Surgery

The researchers are doing this study to find out whether giving methadone during spinal surgery helps manage pain in the first 72 hours after surgery better than other standard pain medications

  • 04 Oct, 2022
  • 1 location
Determining the Feasibility of Outpatient Parenteral Antibiotic Therapy for Persons Who Inject Opioids

patients may be safely included in home OPAT programs when they are provided with medications for opioid use disorder such as suboxone or methadone. However nothing is known about the effect of additional

  • 20 Apr, 2022
  • 1 location
rTMS, Stress and Opioid Use Disorder (TOTS)

(rTMS) might improve treatment outcomes for people with OUD entering methadone treatment. The investigators will examine the impact of rTMS treatment over one of two theoretically-driven neural targets

  • 12 May, 2022
  • 1 location
Clinical Trials of Multivalent Opioid Vaccine Components

Currently, abuse of prescription opioid analgesics and heroin is a serious problem in the U.S. Although several medications, including methadone, buprenorphine, and naltrexone, are available and

Accepts healthy volunteers
  • 04 Oct, 2022
Light Needle for Opioid Use Disorder (OUD)

This randomized-controlled study investigates the effect of adjuvant light needle in the treatment of heroin addicts. One hundred heroin addicts older than 20 years old enrolled from Addiction Treatment Center are randomly allocated to experimental or control group. Subjects in experimental group are treated with light needle on the wrist …

  • 01 May, 2022
  • 1 location