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Found 203 clinical trials
Optimal Nutrition for Prevention of Hypertension in Pregnancy

The aim of this study is to investigate the role of the 677CT polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene on blood pressure (BP) during pregnancy, and to examine the effect of intervention with riboflavin, alone or in combination with 5-methyltetrahydrofolate (5-MTHF), as a non-drug approach for managing BP in …

  • 0 views
  • 28 Jan, 2021
  • 3 locations
Improve PAD PERformance With METformin (PERMET)

The PERMET trial will determine whether metformin daily for six months improves six-minute walk performance in individuals with peripheral artery disease compared to placebo.

arteriopathy
peripheral arterial diseases
  • 46 views
  • 25 Feb, 2022
  • 3 locations
Metformin in Dengue With Obesity

This study aims to investigate the effect of metformin as host-directed therapy in obese/overweight patients with dengue Primary Objective To evaluate the safety and tolerability

fever
dengue
metformin
  • 0 views
  • 18 Oct, 2021
  • 1 location
Metformin in Alzheimer's Dementia Prevention (MAP)

MAP will be a multisite phase II/III 1:1 randomized controlled trial (RCT) of long acting metformin (reduced mass Glucophage XR) vs. matching placebo in 370 men and women with early and late

Accepts healthy volunteers
  • 8 views
  • 06 Jun, 2022
  • 10 locations
Metformin in Children With Fragile X Syndrome

This study is a controlled trial of metformin in children with fragile X syndrome(FXS). The age of FXS children range from 2 to 16 years old. Participants will be randomized in a double-blind

  • 0 views
  • 24 Mar, 2022
  • 1 location
A Clinical Trial of Metformin to Decrease Glucocorticoids Side Effects in Patients With Autoimmune Uveitis

This project is designed to evaluating the use of combination therapy of glucocorticoid and metformin to decrease glucocorticoid side effects in participants with autoimmune uveitis.This study

  • 0 views
  • 17 May, 2022
  • 1 location
Effects of Metformin on Low Back Pain

The purpose of the current study is to determine the effects of metformin in non-diabetic patients with low back pain, and identify novel targets for future treatments

low back pain
back pain
  • 38 views
  • 12 Mar, 2022
  • 2 locations
Antecedent Metabolic Health and Metformin Aging Study (ANTHEM)

Aging is the number one risk factor for the majority of chronic diseases. There are no pharmaceutical treatments to slow aging and prolong healthspan. The anti-diabetic drug metformin is

muscle biopsy
insulin
a 12
metformin
Accepts healthy volunteers
  • 196 views
  • 26 Feb, 2022
  • 2 locations
Metformin as RenoProtector of Progressive Kidney Disease (RenoMet)

A multi-center, practice-oriented, repurposing, double-blinded, placebo-controlled, randomized clinical trial. The RenoMet trial is repurposing an already approved agent (Metformin , Glucophage

proteinuria
glomerular filtration rate
nephropathy
  • 2 views
  • 02 Mar, 2022
  • 9 locations
Metformin to Treat Corticosteroids-induced Hyperglycemia

betamethasone was shown to induce both maternal hyperglycemia and neonatal hypoglycemia, to date, there is insufficient data to establish whether treatment for maternal hyperglycemia, particularly, metformin

  • 0 views
  • 25 Jan, 2021
  • 1 location