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Found 207 clinical trials
Effectiveness of CGMS vs. Self-monitoring Blood Glucose (SMBG) in Woman With Gestational Diabetes

The detection of and control of gestational diabetes carries benefits for both mother and baby related to immediate pregnancy outcomes. The glycemic disorders in diabetes are not solely limited to fasting and postprandial hyperglycemia, but can be extended to the glycemic variability that includes both upward (postprandial glucose increments) and …

  • 0 views
  • 29 Oct, 2021
  • 1 location
Diluted Insulin in Young Children: Bigger Volumes for Smaller Patients

The aim of this study is to compare the pharmacokinetic (PK) profile of diluted insulin aspart (U25) with undiluted insulin aspart (U100) in school-aged children and adolescents with type 1 diabetes (T1D) utilizing the euglycemic clamp technique and a standardized meal in a controlled research environment. The investigators hypothesize that …

  • 6 views
  • 06 Jun, 2022
  • 1 location
Investigational Study of Delayed Release Metformin (DREAM-T2D)

In Phase 1 and 2 studies already conducted, Metformin DR, with its targeted delivery to the distal small intestine, has shown the potential to be a safe and effective way to improve glycemic

  • 5 views
  • 14 Jun, 2022
  • 62 locations
"MetCool ACS"- Metformin "Cooling" Effect on Metformin-naive Patients Treated With PCI Because of Acute Coronary Syndrome

The aim of the study is the evaluation of the effect of metformin among the patients without diabetes, on the incidence of reintervention, unplanned revascularization, after full percutaneous

acute coronary syndrome
percutaneous coronary intervention
coronary revascularization
hba1c
diabetes
  • 0 views
  • 08 Apr, 2022
  • 1 location
Chiglitazar Added to Metformin for Type 2 Diabetes

The purpose of the trial is to evaluate the effect of Chiglitazar added to metformin to type 2 diabetes Inadequately controlled with metformin Monotherapy.

metformin
fasting
hemoglobin a1c
  • 0 views
  • 29 Apr, 2022
  • 50 locations
SGLT2 Inhibitor or Metformin as Standard Treatment of Early Stage Type 2 Diabetes (SMARTEST)

A real-world, nationwide, register-based, randomised trial (RRCT) comparing SGLT2 inhibitors with metformin as standard treatment in early typ 2 diabetes. An open-label trial addressing efficacy

metformin
sglt2 inhibitor
dapagliflozin
sglt2
  • 78 views
  • 09 Feb, 2022
  • 1 location
Metformin and Prevention of Cardiovascular Events in Patients With Acute Myocardial Infarction and Prediabetes (MIMET) (MIMET)

Prediabetes is associated to an increased risk of cardiovascular disease and mortality. Although metformin can delay progression to diabetes there is a lack of RCTs evaluating the effect of

metformin
cardiovascular disease
plasma glucose
hemoglobin a1c
acute myocardial infarction
  • 0 views
  • 23 Mar, 2022
  • 1 location
Safety and Efficacy of PB-119 in Subjects With Type 2 Diabetes and Not Well-controlled by Metformin Monotherapy

) not well-controlled by metformin monotherapy.

metformin
glucagon
hemoglobin a1c
  • 0 views
  • 28 Oct, 2021
  • 1 location
COVID-OUT: Early Outpatient Treatment for SARS-CoV-2 Infection (COVID-19)

The purpose of this trial is to understand whether: Metformin vs fluvoxamine vs ivermectin vs metformin+fluvoxamine vs metformin+ivermectin is superior to placebo in non

  • 21 views
  • 14 Mar, 2022
  • 8 locations
PRuDENTE; Diabetes Prevention Via Exercise Nutrition and Treatment

The PRuDENTE study proposes to assess if metformin therapy a viable, efficient and cost-effective intervention to decrease the incidence of type 2 diabetes (DMT2) in adult subjects with obesity

antihypertensive drugs
type 2 diabetes mellitus
hypertension
body mass index
metformin
  • 107 views
  • 22 Jan, 2021
  • 2 locations