Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 243 clinical trials
An Efficacy and Safety Study of Erdafitinib (JNJ-42756493) in Participants With Urothelial Cancer

The purpose of this study is to evaluate the objective response rate (complete response [CR]+ partial response [PR]) of the selected dose regimen in participants with metastatic or surgically unresectable urothelial cancers that harbor specific FGFR genomic alterations.

erdafitinib
adjuvant chemotherapy
renal function
measurable disease
dose regimen
  • 40 views
  • 03 Mar, 2021
  • 148 locations
Metformin in Patients With Fragile X

The purpose of this trial is to investigate the use of metformin in the treatment of Fragile X syndrome (FXS) patients. Metformin is an FDA approved compound with an established safety profile

mood stabilizers
stimulant
seizure
antipsychotics
antidepressants
  • 35 views
  • 23 Jan, 2021
  • 1 location
Tolerance & Responsiveness Improvement for Metformin (TRIM)

The overall goal is to explore the hypothesis that prebiotic fiber Psyllium will ameliorate diarrhea in African American men (AAM) with Type2 Diabetes Mellitus (T2D).

  • 2 views
  • 24 Jan, 2021
  • 1 location
Metformin in Patients With Non-Alcoholic Fatty Liver Disease (NAFLD)

The purpose of this study is to examine the effect of metformin on biochemical and histological findings in NAFLD patients with insulin resistance syndrome.

fatty liver
insulin
diabetes
  • 8 views
  • 07 Nov, 2020
  • 1 location
Simvastatin and Metformin Therapy in PCOS Women. Prospective Randomised Trial.

The purpose of this study is to compare effects of statins (simvastatin) and metformin on clinical (menstrual cycle, excessive hair, skin problems), endocrine (androgens), metabolic

hirsutism
hydroxyprogesterone
acne
testosterone
progesterone
  • 100 views
  • 07 Nov, 2020
  • 1 location
  • 0 views
  • 28 Jan, 2021
  • 1 location
Trial Comparing Metformin Versus Placebo in Non Alcoholic Steatohepatitis (NASH) Patients Receiving Bariatric Surgery for Obesity

This is a comparison of metformin versus placebo in NASH patients receiving bariatric surgery for obesity.

bariatric surgery
metformin
  • 1 views
  • 07 Nov, 2020
  • 1 location
A Trial of Pembrolizumab and Metformin Versus Pembrolizumab Alone in Advanced Melanoma

The purpose of this study is to evaluate the effectiveness and safety of the combination of Pembrolizumab (KEYTRUDA) and the investigational drug, Metformin.

pembrolizumab
measurable disease
aptt
nivolumab
investigational drug
  • 0 views
  • 27 Jan, 2021
  • 1 location
The Efficacy and Safety of DWP16001 in Combination With Metformin in Patients With Type 2 Diabetes.

Therapeutic Confirmatory Study to Evaluate the Efficacy and Safety of DWP16001 in Combination with Metformin in Patients With Type 2 Diabetes Mellitus who Have Inadequate Glycemic Control on

  • 0 views
  • 27 Jan, 2021
  • 1 location
The AMPK Modulator Metformin as a Novel Adjunct to Conventional Therapy in Patients With Knee Osteoarthritis

metformin alleviates drug-induced osteoarthritis (OA)-like change in mice knee joint through activating autophagy and downregulating apoptosis. Metformin exerts its protective effects against OA

  • 0 views
  • 28 Feb, 2021
  • 1 location