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Found 206 clinical trials
Efficacy and Safety of Metformin Versus Empagliflozin on Chronic Kidney Disease Progression

This randomized controlled trial aims at evaluating the efficacy and safety of the antidiabetics metformin versus empagliflozin on chronic kidney disease (CKD) progression in patients with CKD

  • 0 views
  • 27 May, 2022
  • 1 location
Efficacy of 1% Metformin Gel Mixed With PRF in Augmenting Narrow Ridge (MF)

This study aimed to evaluate the efficacy of 1% metformin gel mixed with PRF, in horizontal ridge augmentation with the split-crest technique, for implant placement.

Accepts healthy volunteers
  • 0 views
  • 28 Jun, 2022
Safety and Efficacy of THR-1442 Compared to Dapagliflozin as Add-on Therapy to Metformin in T2DM

The purpose of this study is to investigate the effect of THR-1442 compared to Dapagliflozin as an add-on therapy to metformin in lowering hemoglobin A1c (HbA1c) levels in subjects with type 2

  • 0 views
  • 22 Dec, 2021
  • 6 locations
Drug Repurposing for the Prevention of Chemotherapy-induced Peripheral Neuropathy (CIPN)

Chemotherapy cause many adverse events including induction of peripheral neuropathy. Metformin, the AMPK activator, was found to have protective effect against chemotherapy induced peripheral

  • 0 views
  • 04 Aug, 2021
  • 1 location
TRE in Type 2 Diabetes (See Food Study 3) (SFS3)

Hyperglycemia in patients with Type 2 Diabetes Mellitus is initially treated with metformin coupled with intentional caloric restriction, which is difficult to sustain due to multiple barriers

Accepts healthy volunteers
  • 0 views
  • 29 Jun, 2022
  • 1 location
A Phase 3 Study to Evaluate the Efficacy and Safety of ORMD-0801 in Subjects With Type 2 Diabetes Mellitus

This double-masked placebo-controlled study will include approximately 450 subjects with inadequately controlled T2DM on diet control alone or on diet control and metformin monotherapy. Subjects

  • 0 views
  • 02 May, 2022
  • 1 location
Effects of Short-term Intensive De-escalation Therapy on Long-term Regimen Simplification (ESTIMATOR)

therapeutic decision making that lags behind glycemic rise. The investigators design this study and presume that using vildagliptin and metformin in combination with basal insulin as sequential treatment

  • 0 views
  • 26 Apr, 2022
Managing DIabetes Remission After Combined Therapy in EarLy Stage of DiabetEs

of a 4-month polychemotherapy (metformin+pioglitazone+sitagliptin+empagliflozin) regimen vs standard care in patients with newly diagnosed T2DM by an open label, pragmatic RCT. Mechanisms of action

  • 2 views
  • 23 Aug, 2021
  • 1 location
The Effect of Dapagliflozin on Platelet Function testinG Profiles in Diabetic PatiEnts.

Sodium GLucose Transport 2 inhibitors (SGLT2I), including dapagliflozin, reduce the likelihood of hospitalization for heart failure and death in persons with type 2 diabetes, of which the mechanism has not been fully elucidated. The mechanistic effects of dapagliflozin on platelet function profiles have not yet been ascertained. It remains unclear …

  • 14 views
  • 26 Jan, 2021
  • 1 location
Effect of Cassia Cinnamon on Arterial Stiffness Parameters in Patients With Type 2 Diabetes Mellitus

Type 2 diabetes mellitus is considered a serious public health problem that has been raising worldwide. In Mexico, it is an important cause of morbi - mortality and its characterized by hyperglycemia that promotes an increase of cardiovascular risk through the impairment of arterial stiffness and endothelial function, which, in …

  • 0 views
  • 26 Feb, 2022
  • 1 location