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Found 98 clinical trials
Platinum Chemotherapy Plus Paclitaxel With Bevacizumab and Atezolizumab in Metastatic Carcinoma of the Cervix

The study will integrate the efficacy of combining the anti programmed death-ligand 1 (anti-PD-L1) agent atezolizumab with the current standard of care in Stage IVB , persistent or recurrent carcinoma of the cervix, namely cisplatin or carboplatin/paclitaxel/bevacizumab. It will be explored the combination of bevacizumab plus atezolizumab, with no patient …

  • 62 views
  • 26 Jan, 2021
  • 90 locations
Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer The PDIGREE Study

This phase III trial compares the usual treatment (treatment with ipilimumab and nivolumab followed by nivolumab alone) to treatment with ipilimumab and nivolumab, followed by nivolumab with cabozantinib in patients with untreated renal cell carcinoma that has spread to other parts of the body. The addition of cabozantinib to the …

cabozantinib
systemic therapy
tumor cells
nivolumab
metastatic renal cell carcinoma
  • 157 views
  • 07 Mar, 2021
  • 653 locations
Serial Ultrasound in Metastatic Renal Cell Carcinoma (mRCC)

To assess whether changes in quantitative tumor perfusion parameters after 3 weeks of treatment, as measured by power doppler ultrasound, can predict initial objective response, defined by current standard-of-care, to therapy at 12 weeks after start of treatment

  • 0 views
  • 18 Feb, 2021
  • 1 location
Talazoparib and Avelumab in Participants With Metastatic Renal Cell Carcinoma

The purpose of this study is to see whether the combination of avelumab and talazoparib can be an effective treatment for metastatic renal cell carcinoma.

metastatic renal cell carcinoma
renal function
metastasis
carcinoma
measurable disease
  • 2 views
  • 29 Jan, 2021
  • 8 locations
SBRT With Combination Ipilimumab/Nivolumab for Metastatic Kidney Cancer

treatment of metastatic kidney cancer.

kidney cancer
ipilimumab
nivolumab
cancer
metastasis
  • 0 views
  • 03 Mar, 2021
  • 7 locations
Study of TAK-228 In Patients With Previously Treated Metastatic Renal Cell Carcinoma

This research study is investigating a drug as a possible treatment for metastatic renal cell carcinoma. The intervention involved in this study is TAK-228.

metastatic renal cell carcinoma
cancer
metastasis
carcinoma
liver metastasis
  • 280 views
  • 27 Jan, 2021
  • 7 locations
Pazopanib Hydrochloride and Bevacizumab in Treating Patients With Previously Untreated Metastatic Kidney Cancer

This phase I/II trial studies the side effects and best dose of pazopanib hydrochloride and bevacizumab and to see how well they work in treating patients with previously untreated kidney cancer that has spread to other places in the body (metastatic). Pazopanib hydrochloride may stop the growth of tumor cells …

aptt
tumor cells
metastatic renal cell carcinoma
metastasis
carcinoma
  • 114 views
  • 25 Jan, 2021
  • 4 locations
Study of Pembrolizumab and Cabozantinib in Patients With Metastatic Renal Cell Carcinoma

This is a phase I/II open-label study designed to evaluate the combination of pembrolizumab and cabozantinib in subjects with locally advanced, recurrent, or metastatic renal cell carcinoma

pd-l1
cabozantinib
metastasis
  • 17 views
  • 25 Jan, 2021
  • 5 locations
Nivolumab in Combination With Ipilimumab in Patients With Metastatic Renal Cell Carcinoma

objective of the trial is to determine the efficacy of combination immunotherapy of nivolumab and ipilimumab in patients with metastatic renal cell carcinoma. The expansion phase shall address the

EGFR
nivolumab
metastatic renal cell carcinoma
renal function
metastasis
  • 83 views
  • 07 Mar, 2021
  • 20 locations
Intermittent Therapy in Metastatic Renal Cell Carcinoma Patients Treated With Ipilimumab and Nivolumab

This study is being done with patients with advanced kidney cancer (also called renal cell carcinoma or RCC). This is a research study involving the use of the drug Nivolumab (also known as Opdivo). Nivolumab is an anti-PD-1 antibody. It works by attaching to and blocking a molecule called PD-1. …

nivolumab
measurable disease
ipilimumab
neutrophil count
interleukin-2
  • 1 views
  • 26 Jan, 2021
  • 1 location