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Found 97 clinical trials
Software Monitoring of Treatment Related Toxicities in Advanced Renal Cell Carcinoma

metastatic renal cell carcinoma (RCC). Additionally for collection of preliminary data on treatment-related toxicities, quality of life, distress level, and drug adherence.

  • 1 views
  • 29 Jan, 2021
  • 1 location
A Proof of Principle Study of Pembrolizumab With SBRT in TKI mRCC Patients

active to warrant further investigation in randomized phase II or III studies. Metastatic renal cell cancer (mRCC) patients with PD-1 expressing immune cells are more likely to have larger more

  • 0 views
  • 26 Jan, 2021
  • 3 locations
Phase I Tolerability Efficacy and Safety Study of Pazopanib in Combination With PCI-24781 in Patients With Metastatic Solid Tumors

This is a open-label non-randomized, dose escalation and expansion Phase Ia/Ib study to determine the safety, tolerability and maximum tolerated dose (MTD) of pazopanib in combination with PCI-24781 in patients with advanced solid tumors.

  • 0 views
  • 26 Jan, 2021
  • 1 location
Molecular Determinants for Therapy Response on Renal Cell Carcinoma

Aim of the scientific analysis is to find biological factors (biomarkers) allowing a prediction of disease progression and a better choice of therapy. After diagnosis the kidney and the tumor will be removed by standard surgery followed by drug therapy. Within surgery remaining tumor tissue will be used for the …

everolimus
bevacizumab
carcinoma
kidney cancer
biological factors
  • 28 views
  • 08 Nov, 2020
Study of Nivolumab in Combination w Radium-223 in Men w Metastatic Castration Resistant Prostate Cancer

This is an open label, prospective, trial that begins with a phase Ib safety run-in followed by a phase II expansion cohort.

prostate adenocarcinoma
nivolumab
platelet count
adenocarcinoma
neutrophil count
  • 0 views
  • 26 Jan, 2021
  • 1 location
Randomized Phase-II Study of Nivolumab Plus Ipilimumab vs. Standard of Care in Untreated and Advanced Non-clear Cell RCC

SUNNIFORECAST (Sunitinib vs. Nivolumab + Ipilimumab as First line treatment Of REnal cell CAncer of non-clear cell SubTypes) is a Phase II, randomized, open-label investigator initiated trial (IIT) of Nivolumab (BMS-936558) combined with Ipilimumab vs standard of care in subjects with previously untreated and advanced (unresectable or metastatic) non-clear cell …

ipilimumab
fine needle aspiration
nivolumab
platelet count
measurable disease
  • 116 views
  • 25 Jan, 2021
  • 41 locations
Gevokizumab With Standard of Care Anti-cancer Therapies for Metastatic Colorectal Gastroesophageal and Renal Cancers

therapy in patients with metastatic colorectal cancer, metastatic gastroesophageal cancer and metastatic renal cell carcinoma.

oxaliplatin
fluorouracil
carcinoma
folfiri regimen
kidney cancer
  • 74 views
  • 03 Mar, 2021
  • 40 locations
PROMOTE: Identifying Predictive Markers of Response for Genitourinary Cancer

with sub-optimal PSA nadir >0.2 ng/ml, (R) metastatic renal cell carcinoma and metastatic and (U) urothelial carcinoma.

metastatic prostate cancer
enzalutamide
carcinoma
bone scan
prostate carcinoma
  • 7 views
  • 28 Jan, 2021
  • 1 location
Nivolumab in Treating Patients With Localized Kidney Cancer Undergoing Nephrectomy

This phase III trial compares nephrectomy (surgery to remove a kidney or part of a kidney) with nivolumab to the usual approach of nephrectomy followed by standard post-operative follow-up and monitoring, in treating patients with kidney cancer that is limited to a certain part of the body (localized). Nivolumab is …

a 12
hepatitis
programmed cell death 1 ligand 1
carcinoma
oophorectomy
  • 351 views
  • 03 Mar, 2021
  • 270 locations
An Investigation of Kidney and Urothelial Tumor Metabolism in Patients Undergoing Surgical Resection and/or Biopsy

The purpose of this study is to understand the metabolism of cancers involving the kidney, including renal cell carcinomas and urothelial cell carcinomas, and how kidney cancers use different types of fuel to support tumor growth. This study uses specially labeled nutrient tracers of compounds normally found circulating in the …

  • 0 views
  • 26 Jan, 2021
  • 1 location