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Found 100 clinical trials
Paricalcitol Plus Gemcitabine and Nab-paclitaxel in Metastatic Pancreatic Cancer

This research study is a two stage study which consists of a safety run-in phase and a randomized phase 2 study which include subjects with previously-untreated, metastatic pancreatic adenocarcinoma. In the run-in safety study, the safety of adding two formulations (IV or Oral) of paricalcitol to a standard chemotherapy program …

cancer chemotherapy
carcinoma
measurable disease
pancreatic adenocarcinoma
neutrophil count
  • 0 views
  • 03 Jul, 2022
  • 1 location
iExosomes in Treating Participants With Metastatic Pancreas Cancer With KrasG12D Mutation

This phase I trial studies the best dose and side effects of mesenchymal stromal cells-derived exosomes with KrasG12D siRNA (iExosomes) in treating participants with pancreatic cancer with KrasG12D mutation that has spread to other places in the body. iExosomes may work better at treating pancreatic cancer.

  • 4 views
  • 14 May, 2022
  • 1 location
Tumor Subtypes in Subjects on FOLFIRINOX With Non-Metastatic Pancreatic Cancer

This is a research study to evaluate how the genetic makeup of Pancreatic Ductal Adenocarcinoma (PDAC) can affect the response to FDA-approved chemotherapy treatment, FOLFIRINOX, given before surgery to remove the tumor. Certain types of PDAC tumors can be surgically resected (removed). However, not all types of PDACs are resectable, …

chemoradiotherapy
cancer chemotherapy
folfirinox
solid tumour
metastasis
  • 10 views
  • 15 Jun, 2022
  • 1 location
Anlotinib Toripalimab and Nab-paclitaxel in Locally Advanced/Metastatic Pancreatic Cancer

pancreatic cancer. Totally 53 patients with locally advanced or metastatic pancreatic cancer are to be enrolled and receive anlotinib plus toripalimab and nab-paclitaxel.

paclitaxel
cancer chemotherapy
metastatic pancreatic cancer
  • 0 views
  • 22 Aug, 2021
  • 1 location
Study of CRS-207, Pembrolizumab, Ipilimumab, and Tadalafil in Metastatic Pancreatic Cancer

The purpose of this study is to evaluate the safety and clinical activity of tadalafil, pembrolizumab, ipilimumab, and CRS-207 in subjects with metastatic pancreatic adenocarcinoma who have progressed after at least 1 prior chemotherapy regimen.

cancer chemotherapy
adenocarcinoma
metastatic pancreatic cancer
metastatic pancreatic adenocarcinoma
pancreatic adenocarcinoma
  • 0 views
  • 12 Jul, 2022
  • 1 location
Timing of Start of systemIc Treatment for Asymptomatic Metastasized Pancreatic Cancer

Since patients with metastatic pancreatic cancer have a limited life expectancy, it is important to determine the timing of when to start chemotherapy in order to optimize the benefits of

  • 0 views
  • 31 May, 2021
  • 1 location
A Study of Gemcitabine, Nab-paclitaxel, Capecitabine, Cisplatin, and Irinotecan in Metastatic Pancreatic Cancer

The purpose of this study is to evaluate the clinical activity of gemcitabine, nab-paclitaxel, capecitabine, cisplatin, and irinotecan (GAX-CI) in patients with metastatic pancreatic cancer.

gemcitabine
irinotecan
metastatic pancreatic cancer
capecitabine
measurable lesion
  • 81 views
  • 10 Mar, 2022
  • 1 location
Niraparib in Metastatic Pancreatic Cancer After Previous Chemotherapy (NIRA-PANC): a Phase 2 Trial (NIRA-PANC)

The goal of this clinical research study is to learn if Niraparib can help to control metastatic pancreatic cancer. The safety of this drug will also be studied. Niraparib is FDA approved and

cancer chemotherapy
adenocarcinoma
metastatic pancreatic cancer
measurable disease
pancreatic cancers
  • 0 views
  • 09 Jun, 2022
  • 6 locations
Disulfiram and Chemotherapy in Treating Patients With Refractory Solid Tumors or Metastatic Pancreatic Cancer

. It is not yet known whether giving chemotherapy with or without disulfiram is a better treatment for refractory solid tumors or metastatic pancreatic cancer.

solid tumor
progesterone
international normalized ratio
serum pregnancy test
metastasis
  • 4 views
  • 17 Jun, 2022
  • 3 locations
Telemedicine in the Management of Pain in Patients With Advanced or Metastatic Pancreatic Cancer (PANTELO)

interest and feasibility of telemedicine in the management of pain in patients undergoing treatment for advanced or metastatic pancreatic cancer.

chemotherapy regimen
adenocarcinoma
analgesics
metastatic adenocarcinoma
cancer
  • 0 views
  • 18 May, 2022
  • 1 location