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Found 513 clinical trials
A Biospecimen Collection Study of Leukapheresis-Derived Circulating Tumor Cells, Immune Cells, and Progenitor Cells.

Primary Objective: This is a study to investigate the feasibility of harvesting, expanding, and selecting T lymphocytes from cancer patients and healthy volunteers. The preliminary objective of this study is aimed at selecting PD-1+ and CTLA4+ T cells and other cellular fractions from peripheral blood of cancer patients and healthy …

liver metastasis
metastasis
solid tumor
cancer
tumor cells
  • 41 views
  • 16 May, 2022
  • 1 location
Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer

This study collects and studies tissue and blood samples from patients with prostate or bladder/urothelial cancer that has recurred (come back) at or near the same place as the original (primary) tumor or has spread to other parts of the body. Studying samples of blood and tissue samples from patients …

platelet count
transurethral resection
metastasis
bone metastases
cancer
  • 97 views
  • 11 Jul, 2022
  • 1 location
The 1200 Patients Project: Studying the Implementation of Clinical Pharmacogenomic Testing

The purpose of this study is to collect DNA samples from patients undergoing routine care at the University of Chicago. These samples will be tested for differences in genes that may suggest greater risk of side effects or chance of increased benefit from certain medications. The results will be made …

enteropathy
cancer
Accepts healthy volunteers
  • 54 views
  • 22 Mar, 2022
  • 1 location
Integrated Cancer Repository for Cancer Research (iCaRe2)

The iCaRe2 is a multi-institutional resource created and maintained by the Fred & Pamela Buffett Cancer Center to collect and manage standardized, multi-dimensional, longitudinal data and biospecimens on consented adult cancer patients, high-risk individuals, and normal controls. The distinct characteristic of the iCaRe2 is its geographical coverage, with a significant …

cancer
Accepts healthy volunteers
early diagnosis
primary cancer
early detection
  • 1433 views
  • 13 Mar, 2022
  • 61 locations
Microbiome Immunotherapy Toxicity and Response Evaluation

This is a observational study to investigate how the microbiome correlates with efficacy and toxicity of immune checkpoint inhibitors in patients with advanced cancer.

immune checkpoint inhibitor
immunomodulators
cytotoxic t-lymphocyte antigen 4
vascular endothelial growth factor
cancer treatment
  • 0 views
  • 10 Dec, 2021
  • 9 locations
Prospective Evaluation of Genetic and Epigenetic Alterations in Patients With Thoracic Malignancies

Background Chromatin is is the structural building block of a chromosome. It is found inside the nucleus of the cell and consists of a complex of DNA and protein. Cancers of the lung, pleura (lung lining) and esophagus show profound changes in chromatin structure that may affect the course of …

metastasis
withdrawn
lung carcinoma
cancer
esophagus cancer
  • 139 views
  • 28 Oct, 2022
  • 1 location
Machine Learning Model to Predict HOLS and Mortality After Discharge in Hospitalized Oncologic Patients (PLANTOLOGY)

The study aims to understand which are the most relevant parameters at admission which may allow to predict the hospital length of stay (HOLS) and mortality after discharge of oncologic hospitalized patients. This is the first multicentric prospective observational study that tries to understand the complexity of the hospitalized oncologic …

primary cancer
  • 0 views
  • 07 Oct, 2022
  • 3 locations
Detection of Genetic Markers of Lung Cancer

The purpose of this research study is to determine the genetic changes and immunologic changes that are involved in the development and progression of lung cancer.

metastasis
lung carcinoma
lung cancer
cancer
lung metastases
  • 14 views
  • 23 Jan, 2022
  • 1 location
Patient-Derived Models Tissue Procurement Protocol for the National Cancer Institute (NCI)

This research trial collects and stores tissue and blood samples from patients with cancer. Collecting and storing samples of tissue and blood from patients with cancer to study in the laboratory may help scientists create new and better models to learn about cancer and to test new cancer drugs.

metastasis
solid tumor
tumor markers
ct scan
primary cancer
  • 86 views
  • 23 Oct, 2022
  • 15 locations
Circulating Tumor DNA as Marker for Response to Antineoplastic Treatment of Metastatic Cancer (FLUIDO)

Early monitoring of antineoplastic treatment benefit is a central medical need. Radiologic assessment for documentation of response is done after several months of treatment usually. This implies that patients not responding are exposed to unnecessary toxicity. According to several reports showing the correlation of the amount of circulating tumour DNA …

  • 0 views
  • 18 Mar, 2021
  • 1 location