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Found 453 clinical trials
The Role Of Circulating Tumor Cells As Markers Of Advanced Disease And Prognosis In HCC

Hepatocellular carcinoma (HCC) recurs in up to 60% of patients who undergo resection. Circulating tumor cells (CTC) have been advocated as promotors of the recurrence. However, their role as prognostic markers in the surgical setting is unclear. The aim of the present study has been to assess the association between …

  • 0 views
  • 23 Mar, 2021
  • 4 locations
18F-Fluciclovine PET Discrimination of Radiation Injury to the Brain

This phase I trial studies the ability and amount of fluciclovine positron emission tomography (PET) imaging needed to recognize tumors that have come back (recurrence) after brain injury from radiation therapy (radionecrosis) in patients with intracranial disease that has spread to other places in the body (metastatic). F-18 fluciclovine is …

  • 0 views
  • 14 Oct, 2022
  • 1 location
The Impact of DNA Repair Pathway Alterations Identified by Circulating Tumor DNA on Sensitivity to Radium-223 in Bone Metastatic Castration-Resistant Prostate Cancer

This phase II study investigates how well radium-223 works in treating patients with castration-resistant prostate cancer than has spread to the bones (bone metastases). Prostate cancer is the most common cancer in men and the second leading cause of cancer death. Furthermore, many men with notably advanced disease have been …

prostate specific antigen
metastasis
castration-resistant prostate cancer
biospecimen collection
testosterone
  • 0 views
  • 27 Oct, 2022
  • 3 locations
Pilot Study to Assess Heterogeneity of the Blood Brain Barrier in Patients With CNS Malignancy

This pilot research trial studies blood brain barrier differences in patients with brain tumors undergoing surgery. Studying samples of tissue and blood from patients with brain tumors in the laboratory may help doctors to understand how well drugs get into different parts of a brain tumor. This may help them …

metastasis
primary brain tumors
brain tumor
renal failure
cns malignancy
  • 0 views
  • 22 Oct, 2022
  • 1 location
The Role of Micrometastasis and Isolated Tumor Cells (ITCs) in Endometrial and Cervical Cancer. A Multicenter Study.

The role of small-volume lymph node disease (ITC and micro metastases) among patients with endometrial or cervical cancer submitted to sentinel node (SLN) procedure is not clearly defined. This study was designed to create a dataset of patients with lymph nodal disease. Data on type and volume of lymph nodal …

metastasis
immunomodulator
lymphadenectomy
cervical cancer stage
cancer
  • 27 views
  • 04 Oct, 2022
  • 1 location
Evaluation of a Novel Microfluidic Device to Purify Metastatic Lung Cancer Patients CTC (Circulating Tumoral Cells)

to determine the performance of the device using patients' blood samples. For this purpose, CTCs from non-small cell lung metastatic cancer patients will be isolated using ClearCellFX1 before

stage iv non-small cell lung cancer
metastasis
liquid biopsy
lung carcinoma
  • 0 views
  • 26 Oct, 2021
  • 1 location
Computer Aided Diagnostic Tool on Computed Tomography Images for Diagnosis of Retroperitoneal Tumor in Children

The aim of this study was to evaluate the diagnostic efficacy of computer aided diagnostic tool for retroperitoneal tumor using machine learning and deep learning techniques on computed tomography images in children.

  • 0 views
  • 21 Mar, 2022
  • 1 location
A Prospective Study of UCAD for Diagnosing Benign or Malignant Biliary Obstruction and Follow-up

Chromosomal instability (CIN) refers to ongoing chromosome segregation errors throughout consecutive cell divisions. CIN is a hallmark of human cancer, and it is associated with poor prognosis, metastasis, and therapeutic resistance. Analyzing CIN of the DNA extracted from bile tract exfoliated cells in bile samples seems a promising method for …

biliary obstruction
carcinoma
metastasis
cancer
endoscopic retrograde cholangiopancreatography
  • 0 views
  • 04 Oct, 2022
  • 1 location
Vascular Fingerprint Validation Study

The vascular fingerprint is a simple selection tool to identify testicular cancer patients with a high risk of arterial cardiovascular events during and in the first year after cisplatin chemotherapy. Eventually, this selection method allows a relative small randomized intervention study with i.e. LMWH during chemotherapy to prove the effectiveness …

  • 215 views
  • 29 May, 2022
  • 5 locations
Prospective Data Registry and Quality of Life Assessment of Patients Undergoing Radiotherapy With the RefleXion Medical Radiotherapy System (PREMIER)

The purpose of this prospective cohort study is to assess clinical and quality of life measures as well as to define the severity of adverse effects for the use of the RefleXion system to deliver intensity-modulated radiotherapy (IMRT), stereotactic body radiotherapy (SBRT), in standard of care (SOC) use in the …

primary cancer
  • 0 views
  • 04 Oct, 2022
  • 2 locations