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Found 25 clinical trials
Detection of Brain Metastasis by MRI in Metastatic Colorectal Cancer Patients

The aim of this study is to prospectively determine the incidence of brain metastases in metastatic colorectal cancer patients using systematic annual screening by MRI.

metastasis
brain metastases
cancer
adenocarcinoma
metastatic colorectal cancer
  • 0 views
  • 26 Jan, 2021
  • 1 location
Development of Clinical and Biological Database in Colorectal Cancer

Creation of circulating cancer cell-lines and caracterisation of these cell-lines which will be collected before any treatment in patients with metastatic colon adenocarcinoma

adenocarcinoma
metastatic colorectal cancer
cancer
  • 1 views
  • 26 Jan, 2021
  • 1 location
Imaging With [89Zr]Panitumumab-PET/MRI in Patients With Newly Diagnosed Colorectal Cancer

This clinical study will investigate the utility of PET imaging with [89Zr]Panitumumab for imaging of EGFR expression in newly diagnosed colon cancer patients to assess lymph node involvement. If promising, this data will be used to design larger trials.

EGFR
cancer
  • 0 views
  • 25 Jan, 2021
  • 1 location
The Value of Palliative Primary Tumor Resection in Metastatic Colon Cancer

The aim of this trial is to evaluate the value of palliative primary tumor resection in colon cancer patients with initially unresectable metastases and a positive response to induction chemotherapy which depends on gene testing. The primary endpoint is to evaluate overall survival.

metastasis
adenocarcinoma of colon
cancer
systemic chemotherapy
adenocarcinoma
  • 0 views
  • 24 Jan, 2021
  • 1 location
A Study of Efficacy and Safety of Fruquintinib (HMPL-013) in Patients With Metastatic Colorectal Cancer

This is a global, randomized, double-blind, placebo-controlled, multicenter phase 3 clinical trial to compare the efficacy and safety of fruquintinib plus best supportive care (BSC) versus placebo plus BSC in patients with refractory metastatic colorectal cancer (mCRC). 687 subjects will be randomized to one of the following treatment arms in …

microsatellite instability high
measurable disease
oxaliplatin
fluoropyrimidine
adjuvant therapy
  • 0 views
  • 30 Mar, 2021
  • 139 locations
TAS-102 and Oxaliplatin for the Treatment of Refractory Stage IV Colon Cancer

This phase II trial studies how well TAS-102 and oxaliplatin work in treating patients with stage IV colon cancer. Drugs used in chemotherapy, such as TAS-102 and oxaliplatin, work in different

ras mutation
measurable disease
absolute neutrophil count
oxaliplatin
tumor cells
  • 0 views
  • 01 Mar, 2021
  • 2 locations
Palbociclib and Cetuximab in Metastatic Colorectal Cancer

This research study is designed to provide a better understanding of study drugs cetuximab (Erbitux) and palbociclib when used in combination to treat patients with metastatic colon cancer.

measurable disease
oxaliplatin
fluoropyrimidine
panitumumab
cetuximab
  • 343 views
  • 25 Jan, 2021
  • 1 location
Autologous Killer Cell Therapy in Colon Cancer Patients

This study aims to evaluate the safety and efficacy of activated and expanded autologous cytokine-killer cells in controlling disease recurrence in colon cancer patients with liver metastasis. 20 patients with confirmed stage IV colon carcinoma with metastasis will be assigned into two groups. Patients in both groups will receive the …

  • 0 views
  • 21 Mar, 2021
  • 1 location
A Study of Bevacizumab Infusional Fluorouracil Leucovorin Oxaliplatin and Irinotecan (A-FOLFOXIRI) Compared With Bevacizumab Infusional Fluorouracil Leucovorin and Irinotecan/Oxaliplatin (A-FOLFIRI/FOLFOX) as First-line Treatment for Metastatic Right-sided Colon Cancer

RATIONALE: Recently, the importance of prognosis according to the location of the primary tumor in colorectal cancer has been raised. In the CALGB / SWOG 80405 study published in 2016, the addition of bevacizumab or cetuximab to the first line FOLFIRI / FOLFOX in KRAS (codon 12, 13) wild type …

  • 0 views
  • 25 Jan, 2021
  • 1 location
SGM-101 in Colorectal Lung Metastases

Near-infrared fluorescence-guided oncologic surgery (FGOS) with the use of a tumor specific tracer (SGM-101) developed by Surgimab can provide valuable intra-operative information about tumor location and extensiveness. SGM-101 already proven to be safe and valuable in colorectal cancer. This study aims to prove feasibility for colorectal lung metastases.

  • 0 views
  • 13 Feb, 2021
  • 2 locations