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Found 15 clinical trials
FOLFOX + Panitumumab According to a "Stop and go" Strategy With a Reintroduction Loop After Progression on Fluoropyrimidine as Maintenance Treatment as the First Line in Patients With Metastatic Colorectal Adenocarcinoma Without a RAS Mutation

Single-arm, multi-centre phase II study The primary objective is to evaluate the time to failure of the strategy.

metastatic colorectal adenocarcinoma
adenocarcinoma
fluoropyrimidine
adjuvant chemotherapy
serum bilirubin level
  • 19 views
  • 28 Feb, 2021
  • 47 locations
Bevacizumab and Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer

RATIONALE: Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Drugs used in chemotherapy, such as irinotecan, fluorouracil, and capecitabine, work in …

monoclonal antibodies
fluorouracil
metastasis
liver metastasis
irinotecan
  • 5 views
  • 07 Nov, 2020
  • 1 location
Evaluation of Ocoxin -Viusid in Metastatic Colorectal Adenocarcinoma

used at a rate of 60 ml daily (1 vial every 12 hours). Our main objective is To evaluate the effect of Ocoxin-Viusid on the quality of life of patients with metastatic colorectal adenocarcinoma. Our

metastatic colorectal adenocarcinoma
white blood cell count
nutritional supplement
leukocyte count
adenocarcinoma
  • 8 views
  • 23 Jan, 2021
  • 1 location
Chemotherapy and/or Metastasectomy in Treating Patients With Metastatic Colorectal Adenocarcinoma With Lung Metastases

colorectal adenocarcinoma with lung metastases.

metastatic colorectal adenocarcinoma
cancer
metastasis
complete resection
platelet count
  • 4 views
  • 01 Feb, 2021
  • 7 locations
  • 0 views
  • 25 Jan, 2021
  • 1 location
Study of Pembrolizumab Binimetinib and Bevacizumab in Patients With Refractory Colorectal Cancer

This is an open-label, single-center, single-arm phase II clinical trial evaluating the combination of pembrolizumab, binimetinib, and bevacizumab in patients with metastatic colorectal

metastatic colorectal adenocarcinoma
pembrolizumab
metastasis
liver metastasis
bevacizumab
  • 19 views
  • 03 Mar, 2021
  • 1 location
Combination Chemotherapy Bevacizumab and/or Atezolizumab in Treating Patients With Deficient DNA Mismatch Repair Metastatic Colorectal Cancer the COMMIT Study

This phase III trial studies how well combination chemotherapy, bevacizumab, and/or atezolizumab work in treating patients with deficient deoxyribonucleic acid (DNA) mismatch repair colorectal cancer that has spread to other places in the body (metastatic). Chemotherapy drugs, such as fluorouracil, oxaliplatin, and leucovorin calcium, work in different ways to stop …

  • 460 views
  • 03 Mar, 2021
  • 323 locations
Phase II Trial of Fruquintinib With Sintilimab in Treating Selected Refractory Metastatic Colorectal Cancer Patients

This is a prospective, Single arm Phase II trial. Patients were eligible to participate when they had histological or cytological confirmed metastatic colorectal adenocarcinoma Non-MSI

  • 0 views
  • 28 Jan, 2021
  • 1 location
Panitumumab With or Without Trametinib in Treating Patients With Stage IV Colorectal Cancer

This phase II clinical trial studies how well panitumumab with or without trametinib works in treating patients with stage IV colorectal cancer. Immunotherapy with monoclonal antibodies, such as panitumumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and …

  • 20 views
  • 23 Jan, 2021
  • 2 locations
Regorafenib With Cetuximab or Panitumumab for the Treatment of Unresectable Locally Advanced or Metastatic Colorectal Cancer

This phase II trial how well regorafenib and anti-EGFR therapy (cetuximab or panitumumab) works for the treatment of patients with colorectal cancer that cannot be removed by surgery (unresectable), has spread to nearby tissue or lymph nodes (locally advanced), or has spread to other places in the body (metastatic). Regorafenib …

  • 0 views
  • 15 Feb, 2021
  • 15 locations