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Found 27 clinical trials
Imaging With [89Zr]Panitumumab-PET/MRI in Patients With Newly Diagnosed Colorectal Cancer

This clinical study will investigate the utility of PET imaging with [89Zr]Panitumumab for imaging of EGFR expression in newly diagnosed colon cancer patients to assess lymph node involvement. If promising, this data will be used to design larger trials.

cancer
EGFR
  • 0 views
  • 25 Jan, 2021
  • 1 location
Detection of Brain Metastasis by MRI in Metastatic Colorectal Cancer Patients

The aim of this study is to prospectively determine the incidence of brain metastases in metastatic colorectal cancer patients using systematic annual screening by MRI.

metastatic colorectal cancer
cancer
adenocarcinoma
brain metastases
metastasis
  • 0 views
  • 26 Jan, 2021
  • 1 location
Development of Clinical and Biological Database in Colorectal Cancer

Creation of circulating cancer cell-lines and caracterisation of these cell-lines which will be collected before any treatment in patients with metastatic colon adenocarcinoma

cancer
adenocarcinoma
metastatic colorectal cancer
  • 1 views
  • 26 Jan, 2021
  • 1 location
Triplezumab Combined With CAPEOX Regimen in Neoadjuvant Therapy for Locally Advanced Colon Cancer

According to the 2019NCCN guidelines, immunocheckpoint inhibitors are recommended for first-line treatment of metastatic colon cancer patients with high microsatellite instability (msi-h) or

  • 0 views
  • 24 Jan, 2021
  • 1 location
Dabrafenib + Trametinib + PDR001 In Colorectal Cancer

This research study is studying a combination of drugs as a possible treatment for metastatic colorectal cancer characterized by BRAF V600E mutation. The names of the study drugs involved in this study are: Dabrafenib Trametinib PDR001

spiral computed tomography
KRAS
measurable disease
BRAF
neutrophil count
  • 1 views
  • 22 Jan, 2021
The Value of Palliative Primary Tumor Resection in Metastatic Colon Cancer

The aim of this trial is to evaluate the value of palliative primary tumor resection in colon cancer patients with initially unresectable metastases and a positive response to induction chemotherapy which depends on gene testing. The primary endpoint is to evaluate overall survival.

systemic chemotherapy
cancer
adenocarcinoma of colon
adenocarcinoma
metastasis
  • 0 views
  • 24 Jan, 2021
  • 1 location
A Study of Efficacy and Safety of Fruquintinib (HMPL-013) in Patients With Metastatic Colorectal Cancer

This is a global, randomized, double-blind, placebo-controlled, multicenter phase 3 clinical trial to compare the efficacy and safety of fruquintinib plus best supportive care (BSC) versus placebo plus BSC in patients with refractory metastatic colorectal cancer (mCRC). Approximately 520 subjects will be randomized to one of the following treatment arms …

microsatellite instability high
oxaliplatin
irinotecan
metastatic colorectal cancer
colorectal adenocarcinoma
  • 0 views
  • 26 Jan, 2021
  • 32 locations
TAS-102 and Oxaliplatin for the Treatment of Refractory Stage IV Colon Cancer

This phase II trial studies how well TAS-102 and oxaliplatin work in treating patients with stage IV colon cancer. Drugs used in chemotherapy, such as TAS-102 and oxaliplatin, work in different

absolute neutrophil count
trifluridine and tipiracil hydrochloride
neutrophil count
ras mutation
fluorouracil
  • 0 views
  • 25 Jan, 2021
  • 2 locations
Palbociclib and Cetuximab in Metastatic Colorectal Cancer

This research study is designed to provide a better understanding of study drugs cetuximab (Erbitux) and palbociclib when used in combination to treat patients with metastatic colon cancer.

irinotecan
metastatic colorectal cancer
adjuvant chemotherapy
colon cancer
metastasis
  • 343 views
  • 25 Jan, 2021
  • 1 location
A Study of Bevacizumab Infusional Fluorouracil Leucovorin Oxaliplatin and Irinotecan (A-FOLFOXIRI) Compared With Bevacizumab Infusional Fluorouracil Leucovorin and Irinotecan/Oxaliplatin (A-FOLFIRI/FOLFOX) as First-line Treatment for Metastatic Right-sided Colon Cancer

RATIONALE: Recently, the importance of prognosis according to the location of the primary tumor in colorectal cancer has been raised. In the CALGB / SWOG 80405 study published in 2016, the addition of bevacizumab or cetuximab to the first line FOLFIRI / FOLFOX in KRAS (codon 12, 13) wild type …

  • 0 views
  • 25 Jan, 2021
  • 1 location