Found 15 clinical trials
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Immune Checkpoint Inhibitor and MR-guided SBRT for Limited Progressive Metastatic Carcinoma.
This is an open label single arm phase 2 clinical trial in patients with metastatic solid malignancy of any histology who have previously experienced limited progression in at least 1 and up to 5 lesions while on immune checkpoint inhibitors monotherapy.
- 0 views
- 11 Apr, 2021
- 1 location
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Multi-country trial
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For females only
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Currently Recruiting
Platinum Chemotherapy Plus Paclitaxel With Bevacizumab and Atezolizumab in Metastatic Carcinoma of the Cervix
The study will integrate the efficacy of combining the anti programmed death-ligand 1 (anti-PD-L1) agent atezolizumab with the current standard of care in Stage IVB , persistent or recurrent carcinoma of the cervix, namely cisplatin or carboplatin/paclitaxel/bevacizumab. It will be explored the combination of bevacizumab plus atezolizumab, with no patient …
- 62 views
- 26 Jan, 2021
- 91 locations
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Pulmonary/Respiratory Diseases
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Currently Recruiting
Anti-HER2 Therapy in Patients of HER2 Positive Metastatic Carcinoma of Digestive System
To seek the efficacy signals of trastuzumab in combination with chemotherapy in pretreated patients of HER2 positive, relapse or metastatic carcinoma of digestive system as response rate (RR
- 7 views
- 22 Jan, 2021
- 1 location
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Phase 1 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For females only
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Currently Recruiting
Study of Niraparib With Radiotherapy for Treatment of Metastatic Invasive Carcinoma of the Cervix
The most effective strategy for managing distantly metastatic invasive carcinomas of the cervix is not defined. Based on the success of niraparib in breast and ovarian cancer trials and the concern for toxicities and comorbidities limiting the compliance of concurrent cisplatin for cervical cancer, this study is a phase I/II …
- 0 views
- 18 Feb, 2021
- 3 locations
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Pulmonary/Respiratory Diseases
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Currently Recruiting
Temozolomide in Preventing Brain Metastases in Small Cell Lung Cancer
To investigate the response of temozolomide versus prophylactic cranial radiotherapy in preventing brain metastases in completed or partial remission limited small cell lung cancer patients.
- 0 views
- 23 Jan, 2021
- 1 location
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Phase 1 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
BMS-986156 Ipilimumab and Nivolumab With or Without Stereotactic Body Radiation Therapy in Treating Patients With Advanced or Metastatic Lung/Chest or Liver Cancers
This phase I/II trial studies the side effects and best dose of anti-glucocorticoid-induced tumor necrosis factor receptor (GITR) agonistic monoclonal antibody BMS-986156 (BMS-986156) when given together with ipilimumab and nivolumab with or without stereotactic body radiation therapy and to see how well they work in treating patients with lung/chest or …
- 1 views
- 01 Feb, 2021
- 1 location
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For males only
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Nephrology
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Currently Recruiting
INTERVAL - Intense Exercise Trial for Men With Metastatic Castrate-Resistant Prostate Cancer
Exercise has been established to be safe and result in improved physical function and quality of life for most individuals with cancer. However, little information exists regarding whether exercise can increase overall survival and reduce disease progression, events related to cancer spreading to the bones (e.g. bone fracture, spinal cord …
- 64 views
- 25 Jan, 2021
- 4 locations
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Pulmonary/Respiratory Diseases
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Currently Recruiting
Combined Deep Inspiration Breath Hold (DIBH)-Expiration Planning Technique in Patients With Lung Tumors in Close Proximity to the Chest Wall
The purpose of this study is to evaluate a new radiation planning and treatment delivery technique called Deep Inspiration Breath Hold (DIBH) and expiration technique. This technique will be used to treat patients who have tumors close to the chest wall and are candidates for Stereotactic Body Radiation Therapy (SBRT). …
- 0 views
- 26 Jan, 2021
- 1 location
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Family Medicine
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Currently Recruiting
Treatment Of Metastatic Bladder Cancer at the Time Of Biochemical reLApse Following Radical Cystectomy
Immunotherapy (checkpoint inhibitors) is approved as first and second line treatment to patients with metastatic bladder cancer. However, response rates are low and no biomarkers have yet shown strong predictive value for patient selection. Moreover, the term 'metastatic' is based on metastases visible on conventional CT scans and, thus, require …
- 0 views
- 27 Mar, 2021
- 5 locations
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Pulmonary/Respiratory Diseases
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Currently Recruiting
Tadalafil and Pembrolizumab in Recurrent or Metastatic Head and Neck Cancer
This study will examine the combination of pembrolizumab and tadalafil for safety and efficacy in advanced head and neck cancer.
- 0 views
- 24 Jan, 2021
- 1 location
- 1
- 2