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Found 10341 clinical trials
Featured trial
A Study to Evaluate the Safety Tolerability and Pharmacokinetics of BIIB094 in Adults With Parkinson's Disease

Parkinson's Disease (PD). The secondary objective of this study is to evaluate the pharmacokinetic (PK) profile of BIIB094.The study is open for PD patients with verified presence or absence of mutations in the

dyskinesia
  • 807 views
  • 18 May, 2022
  • 14 locations
Featured trial
Safety and Tolerability Study of INCB057643 in Participants With Myelofibrosis and Other Advanced Myeloid Neoplasms

The purpose of this study is to evaluate the safety, tolerability, and preliminary efficacy of INCB057643 as monotherapy or combination with ruxolitinib for participants with myelofibrosis and other myeloid neoplasms.

myelofibrosis
cell transplantation
  • 0 views
  • 27 May, 2022
  • 15 locations
Featured trial
Study to Assess the Efficacy Safety and Tolerability of SAR440340/REGN3500/Itepekimab in Chronic Obstructive Pulmonary Disease (COPD) (AERIFY-2)  

-severe COPD exacerbations in former smokers with moderate-to-severe COPD Secondary Objectives: Primary population (former smokers cohort):

  • 215 views
  • 26 May, 2022
  • 51 locations
Featured trial
To Evaluate the Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis (LIMBER-313)

The purpose of the study is to compare the efficacy of parsaclisib when combined with ruxolitinb versus placebo combined with ruxolitinib in participants with myelofibrosis.

  • 0 views
  • 17 May, 2022
  • 101 locations
Featured trial
VAD00001: Respiratory Syncytial Virus (RSV) Study  

Syncytial Virus (RSV) seronegative participants. The secondary objectives of the study are: To quantify the amount of vaccine virus shed by each participant by baseline

Accepts healthy volunteers
  • 248 views
  • 19 May, 2022
  • 17 locations
Featured trial
Study in Parkinson Disease of Exercise (SPARX3)

This study is a Phase 3 multi-site, randomized, evaluator-masked, study of endurance treadmill exercise on changes in the Movement Disorder Society-Unified Parkinson Disease Rating Scale (MDS-UPDRS) Part III score at 12 months among persons with early stage Parkinson disease. 370 participants will be randomly assigned to 2 groups: 1)60-65% HRmax …

SPECT Scan
movement disorder
datscan
  • 146 views
  • 25 Apr, 2022
  • 25 locations
Featured trial
ATLAS: A Randomized, Double-blind, Placebo-controlled Phase 3 Study of JNJ-56021927 in Subjects With High-risk, Localized or Locally Advanced Prostate Cancer Receiving Treatment With Primary Radiation Therapy. NCT02531516, PCR3003.

primary radiation therapy results in an improvement of metastasis-free survival. The study will include a Screening Phase, Treatment Phase, a Posttreatment Phase, and a Long-term Follow-up Phase. 

  • 60 views
  • 02 Sep, 2021
  • 1 location
Featured trial
  • 0 views
  • 10 Mar, 2022
  • 1 location
Featured trial
Pilot Study of Topical Dexamethasone 0.01% Solution for Prevention of Oral Chronic Graft Versus Host Disease

This study will determine if a dexamethasone mouth rinse can reduce the risk of developing oral chronic graft-versus-host disease (cGVHD) in patients who have undergone a bone marrow (stem cell) transplant procedure. cGVHD is a common complication of stem cell transplantation, resulting from the donor cells attacking the transplant recipient's …

graft versus host disease
graft-versus-host disease
  • 160 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Response to the SHINGRIX Varicella Zoster Virus (VZV) Vaccine in Chronic Lymphocytic Leukemia (CLL) Patients that are Treatment Naive or Receiving Bruton s-Tyrosine Kinase Inhibitor (BTK-I) Therapy

Background: People who have cancer tend to get sick more often. This is in part because of the cancer treatments they get. Because of this, they may get shingles. Scientists had thought people with chronic lymphocytic leukemia (CLL) should not get the shingles vaccine. Now there is a new shingles …

cancer
chronic lymphocytic leukemia
acalabrutinib
lymphoma
ibrutinib
  • 228 views
  • 09 Apr, 2019
  • 1 location