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Found 2 clinical trials
Olaparib in Treating Patients With Metastatic Biliary Tract Cancer With Aberrant DNA Repair Gene Mutations

This phase II trial studies how well olaparib works in treating patients with biliary tract cancer that has spread to other places in the body (metastatic) and with aberrant DNA repair gene mutations. Olaparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell …

cancer
hysterectomy
serum pregnancy test
luteinizing hormone (lh)
follicle stimulating hormone
  • 0 views
  • 29 May, 2022
  • 5 locations
Liposomal Irinotecan, Fluorouracil, Leucovorin Calcium, and Rucaparib in Treating Patients With Metastatic Pancreatic, Colorectal, Gastroesophageal, or Biliary Cancer

This phase I/II trial studies the side effects and best dose of liposomal irinotecan and rucaparib when given together with fluorouracil and leucovorin calcium and to see how well they work in treating patients with pancreatic, colorectal, gastroesophageal, or biliary cancer that has spread to other places in the body …

cancer
vasectomy
metastatic adenocarcinoma
homologous recombination deficiency
rucaparib
  • 8 views
  • 16 Jun, 2022
  • 3 locations