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Found 9189 clinical trials
Featured trial
A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients With Advanced Solid Tumors With KRAS G12C Mutation

Evaluates the safety, tolerability, pharmacokinetics, metabolites, pharmacodynamics, and clinical activity of MRTX849 in patients with advanced solid tumors with a KRAS G12C mutation. MRTX849 is an orally-available small molecule inhibitor of KRAS G12C.

advanced solid tumor
malignant solid tumor
solid tumor
  • 538 views
  • 22 Nov, 2021
  • 62 locations
Featured trial
A Phase 1/2 Trial of MRTX849 in Combination with TNO155 in Patients with Advanced Solid Tumors with KRAS G12C Mutation

Characterize the safety and tolerability, and evaluate Pharmacokinetics of MRTX849 in combination with TNO155 in patients with advanced solid tumor malignancies with KRAS G12C mutation. MRTX849 is an orally available small molecute inhibitor of KRASG12C. TNO155 is a selective, orally bioavailable allosteric inhibitor of wild type SHP2.

advanced solid tumor
malignant solid tumor
solid tumors
solid tumor
  • 179 views
  • 19 Feb, 2021
  • 4 locations
Featured trial
  • 690 views
  • 08 Nov, 2020
  • 1 location
Featured trial
Memory Loss Prevention

prevention for those at risk of developing dementia secondary to Alzheimer’s disease even before symptoms occur.Research studies for “memory loss prevention” include those who are at

alzheimer's disease
dementia
  • 29 views
  • 30 Jul, 2021
  • 1 location
Featured trial
Prostate Cancer

Prostate Cancer

  • 76 views
  • 08 Nov, 2020
  • 1 location
Featured trial
PLUS 1 Study

PLUS 1 Study

  • 249 views
  • 08 Nov, 2020
  • 1 location
Featured trial
Enlarged Prostate

Enlarged Prostate

  • 56 views
  • 08 Nov, 2020
  • 1 location
Featured trial
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Selonsertib in Subjects with Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Selonsertib in Subjects with Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis

  • 1167 views
  • 25 Mar, 2021
  • 1 location
Featured trial
A Phase 2, Multicenter, Randomized, Double-blind, Placebo- and Active-controlled Trial of Brexpiprazole (1 - 3 mg/day) as Monotherapy or as Combination Therapy in the Treatment of Adults with Post-traumatic Stress Disorder

A Phase 2, Multicenter, Randomized, Double-blind, Placebo- and Active-controlled Trial of Brexpiprazole (1 - 3 mg/day) as Monotherapy or as Combination Therapy in the Treatment of Adults with Post-traumatic Stress Disorder

  • 1451 views
  • 25 Mar, 2021
  • 1 location
Featured trial
Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer

  • 150 views
  • 08 Nov, 2020
  • 1 location