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Found 11003 clinical trials
Featured trial
Fulfilling the Caregiving Role: Male Perspectives on their Role as Caregivers for Persons with ADRD

explore the experiences of male caregivers caring for a person with ADRD throughout the role transitions from family member to caregiver. The secondary aim of the study is to describe the male caregivers

Accepts healthy volunteers
Online studies
alzheimer's disease
  • 01 Dec, 2021
  • 1 location
  • Online study
Featured trial
A Study to Evaluate the Safety Tolerability and Pharmacokinetics of BIIB094 in Adults With Parkinson's Disease

Parkinson's Disease (PD). The secondary objective of this study is to evaluate the pharmacokinetic (PK) profile of BIIB094.The study is open for PD patients with verified presence or absence of mutations in the

  • 27 Oct, 2021
  • 14 locations
Featured trial
Study in Parkinson Disease of Exercise

This study is a Phase 3 multi-site, randomized, evaluator-masked, study of endurance treadmill exercise on changes in the Movement Disorder Society-Unified Parkinson Disease Rating Scale (MDS-UPDRS) Part III score at 12 months among persons with early stage Parkinson disease. 370 participants will be randomly assigned to 2 groups: 1)60-65% HRmax …

  • 04 Jun, 2021
  • 8 locations
Featured trial
Study to Assess the Efficacy Safety and Tolerability of SAR440340/REGN3500/Itepekimab in Chronic Obstructive Pulmonary Disease (COPD) (AERIFY-2)  

-severe COPD exacerbations in former smokers with moderate-to-severe COPD Secondary Objectives: Primary population (former smokers cohort):

  • 12 Nov, 2021
  • 11 locations
Featured trial
VAD00001: Respiratory Syncytial Virus (RSV) Study  

Syncytial Virus (RSV) seronegative participants. The secondary objectives of the study are: To quantify the amount of vaccine virus shed by each participant by baseline

  • 05 Nov, 2021
  • 17 locations
Featured trial
A Phase 1, Open-Label, Dose-Escalation, Safety, Pharmacokinetic, and Pharmacodynamic Study of Oral TP-3654 in Patients with Intermediate or High-Risk Primary or Secondary Myelofibrosis

This is a Phase 1, multicenter, dose-escalation, open-label study to assess safety, tolerability, preliminary activity, pharmacokinetics and pharmacodynamics of TP-3654 in patients with intermediate-2 or high-risk myelofibrosis.

  • 27 Oct, 2021
  • 5 locations
Featured trial
ATLAS: A Randomized, Double-blind, Placebo-controlled Phase 3 Study of JNJ-56021927 in Subjects With High-risk, Localized or Locally Advanced Prostate Cancer Receiving Treatment With Primary Radiation Therapy. NCT02531516, PCR3003.

primary radiation therapy results in an improvement of metastasis-free survival. The study will include a Screening Phase, Treatment Phase, a Posttreatment Phase, and a Long-term Follow-up Phase. 

  • 02 Sep, 2021
  • 1 location
Featured trial
  • 24 Jun, 2021
  • 1 location
Featured trial
A Prospective, Randomized, Double-masked, Active Comparator-controlled, Multi-center, Two-arm, Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 Compared With Intravitreal Aflibercept in Participants With Visual Impairment Due to Treatment-naïve Macular Edema Secondary to Retinal Vein Occlusion (RVO)

This Phase 3 study will evaluate the efficacy, durability, and safety of KSI-301 compared to aflibercept, in participants with macular edema due to treatment-naïve branch (BRVO) or central retinal vein occlusion (CRVO).

retinal vein occlusion
spectral domain optical coherence tomography
macular edema
  • 24 Jun, 2021
  • 1 location
Featured trial
Pilot Study of Topical Dexamethasone 0.01% Solution for Prevention of Oral Chronic Graft Versus Host Disease

This study will determine if a dexamethasone mouth rinse can reduce the risk of developing oral chronic graft-versus-host disease (cGVHD) in patients who have undergone a bone marrow (stem cell) transplant procedure. cGVHD is a common complication of stem cell transplantation, resulting from the donor cells attacking the transplant recipient's …

graft versus host disease
graft-versus-host disease
  • 22 Dec, 2020
  • 1 location