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Found 18 clinical trials
lead-in FOLICOLOR Trial: Following Therapy Response Through Liquid Biopsy in Metastatic Colorectal Cancer Patients

Detection of progressive disease by neuropeptide Y (NPY) methylation in liquid biopsies in patients with RAS and BRAF wild-type, unresectable, metastatic colorectal cancer receiving first-line treatment FOLFOX/FOLFIRI and panitumumab.

  • 0 views
  • 14 Feb, 2021
  • 6 locations
Metastasis-directed Therapy in Castration-refractory Prostate Cancer

The aim is to define the postponement of next line systemic treatment (NEST), by the use of metastasis-directed therapy in patients with oligoprogressive castration-refractory prostate cancer. This will be defined by the NEST-free survival. Furthermore the investigators will use 18F PSMA PET-CT as investigational imaging, to assess the predictive value …

testosterone level
metastasis
abiraterone
adenocarcinoma
denosumab
  • 0 views
  • 23 Jan, 2021
Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery

This partially randomized phase II/III trial studies how well, in combination with surgery, cisplatin and combination chemotherapy works in treating children and young adults with hepatoblastoma or hepatocellular carcinoma. Drugs used in chemotherapy, such as cisplatin, doxorubicin, fluorouracil, vincristine sulfate, carboplatin, etoposide, irinotecan, sorafenib, gemcitabine and oxaliplatin, work in different …

vincristine
tumor cells
cancer
carboplatin
carcinoma
  • 178 views
  • 27 Mar, 2021
  • 136 locations
Post SBRT Pulmonary Metastasectomy (PSPM) Trial

The goal of this study is to determine the effectiveness of SBRT on reducing tumor viability at a pathologic level and also to evaluate the effects of combined modality treatment on low volume pulmonary metastases, in hopes of extrapolating this information to both primary and secondary lung cancer.

  • 0 views
  • 05 Mar, 2021
  • 1 location
Mediastinal Lymph Node Dissection in Conjunction With Pulmonary Metastasectomy From Colorectal Cancer

To study whether or not total mediastinal lymph node dissection in conjunction with pulmonary metastasectomy from colorectal cancer is associated with improved survival compared to pulmonary

cancer
  • 13 views
  • 21 Jan, 2021
Chemotherapy and/or Metastasectomy in Treating Patients With Metastatic Colorectal Adenocarcinoma With Lung Metastases

This phase II trial studies how well chemotherapy and/or metastasectomy work in treating patients with colorectal adenocarcinoma that has spread to the lungs (metastases). Drugs used in

neutrophil count
cancer
metastasis
tumor cells
metastatic colorectal cancer
  • 4 views
  • 10 May, 2021
  • 7 locations
A Trial Evaluating the Efficacy of Metastasectomy in Patients With Oligo-Metastatic Breast Cancer(OMIT)

This is a randomized clinical trial (OMIT study) evaluating the efficacy of metastasectomy in patients with oligo-metastatic breast cancer.

stage iv breast cancer
metastasis
measurable disease
  • 0 views
  • 25 Jan, 2021
  • 1 location
Hypofractionated Brain Radiationcavity

Stereotactic radiosurgery or hypofractionated radiotherapy of the resection cavity after metastasectomy in cancer patients with brain metastases

  • 10 views
  • 25 Jan, 2021
  • 11 locations
Chemotherapy Alone Versus Surgery Plus Chemotherapy for Distal Gastric Cancer With One Non-curable Factor

Our study aims to compare the efficacy and safety of Chemotherapy Alone Versus D2 distal gastrectomy and metastasectomy plus Chemotherapy for gastric cancer (GC) with one non-curable Factor

lymphadenectomy
capecitabine
metastasis
cancer chemotherapy
gastrectomy
  • 24 views
  • 22 Jan, 2021
  • 9 locations
Trabectedin Plus Radiotherapy in Soft Tissue Sarcoma Patients

unresectable or not oncologically recommended metastasectomy of limited to lung metastases soft tissue sarcoma. Cohort B: Patients with locally advanced resectable Myxoid Liposarcoma. Cohort C: Patients

soft tissue sarcoma
metastasis
trabectedin
mpnst
undifferentiated pleomorphic sarcoma
  • 25 views
  • 24 Jan, 2021
  • 21 locations