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Found 9 clinical trials
Pediatric Hepatic Malignancy International Therapeutic Trial (PHITT)

This partially randomized phase II/III trial studies how well, in combination with surgery, cisplatin and combination chemotherapy works in treating children and young adults with hepatoblastoma or hepatocellular carcinoma. Drugs used in chemotherapy, such as cisplatin, doxorubicin, fluorouracil, vincristine sulfate, carboplatin, etoposide, irinotecan, sorafenib, gemcitabine and oxaliplatin, work in different …

etoposide
carboplatin
fluorouracil
vincristine
tumor cells
  • 192 views
  • 16 Oct, 2022
  • 136 locations
Post SBRT Pulmonary Metastasectomy (PSPM) Trial

The goal of this study is to determine the effectiveness of SBRT on reducing tumor viability at a pathologic level and also to evaluate the effects of combined modality treatment on low volume pulmonary metastases, in hopes of extrapolating this information to both primary and secondary lung cancer.

  • 0 views
  • 05 Mar, 2021
  • 1 location
A Trial Evaluating the Efficacy of Metastasectomy in Patients With Oligo-Metastatic Breast Cancer(OMIT)

This is a randomized clinical trial (OMIT study) evaluating the efficacy of metastasectomy in patients with oligo-metastatic breast cancer.

measurable disease
metastasis
stage iv breast cancer
  • 0 views
  • 25 Jan, 2021
  • 1 location
Hypofractionated Brain Radiationcavity

Stereotactic radiosurgery or hypofractionated radiotherapy of the resection cavity after metastasectomy in cancer patients with brain metastases

  • 10 views
  • 22 Mar, 2022
  • 8 locations
Chemotherapy Alone Versus Surgery Plus Chemotherapy for Distal Gastric Cancer With One Non-curable Factor

Our study aims to compare the efficacy and safety of Chemotherapy Alone Versus D2 distal gastrectomy and metastasectomy plus Chemotherapy for gastric cancer (GC) with one non-curable Factor

gastrectomy
metastasis
lymphadenectomy
oxaliplatin
capecitabine
  • 24 views
  • 31 Jan, 2022
  • 9 locations
Trabectedin Plus Radiotherapy in Soft Tissue Sarcoma Patients (TRASTS)

unresectable or not oncologically recommended metastasectomy of limited to lung metastases soft tissue sarcoma. Cohort B: Patients with locally advanced resectable Myxoid Liposarcoma. Cohort C: Patients

measurable disease
liposarcoma
myxofibrosarcoma
malignant fibrous histiocytoma
angiosarcoma
  • 25 views
  • 17 Jun, 2022
  • 13 locations
Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Soft Tissue or Bone Sarcoma Metastatic to the Lungs

This phase I/II trial studies the side effects of pulmonary suffusion in controlling minimal residual disease in patients with soft tissue or bone sarcoma that has spread to the lungs. Pulmonary suffusion is a minimally invasive delivery of chemotherapeutic agents like cisplatin to lung tissues. Drugs used in chemotherapy, such …

measurable disease
isolated chemotherapeutic lung perfusion
sarcoma
antineoplastic
metastasectomy
  • 0 views
  • 04 Oct, 2022
  • 1 location
Pembrolizumab With or Without Axitinib for Treatment of Locally Advanced or Metastatic Clear Cell Kidney Cancer in Patients Undergoing Surgery

This phase II trial studies how well pembrolizumab with or without standard of care axitinib works in treating patients with clear cell kidney cancer that has spread to nearby tissues or lymph nodes (locally advanced) or other places in the body (metastatic) who are undergoing surgery. Pembrolizumab is an antibody …

measurable disease
vegf
direct bilirubin
anticoagulants
nephrectomy
  • 0 views
  • 12 May, 2022
  • 1 location
TRACERx Renal CAPTURE Sub-study

TRACERx Renal: This is a translational study, which, aims to develop prognostic and predictive biomarkers for patients with renal cell carcinoma (RCC). CAPTURE Sub-study: Covid-19 antiviral response in a pan-tumour immune monitoring study

nephrectomy
carcinoma
cancer diagnosis
cancer
primary cancer
  • 33 views
  • 24 Jan, 2021
  • 4 locations