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Found 270 clinical trials
Featured trial
2 A Day Study

Limiting eating to two daily meals was shown to improve health in mice. By taking part in the 2-A-DAY study, you will help us find out if eating this way is also healthier for humans. If you decide to participate, we will ask you to eat food provided by the …

hemoglobin a1c
  • 02 Jun, 2022
  • 1 location
Hydration to Optimize Metabolism (H2O-metabolism)

This study evaluates hydration (1.5 L of water daily during 1 year) in the lowering of blood glucose concentration in adults with signs of dehydration (elevated levels of the vasopressin marker copeptin and high urine osmolality). Half of participants will in addition to lifestyle advice receive extra water on top …

Accepts healthy volunteers
  • 02 Mar, 2022
  • 1 location
A Phase 1, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single-and-Multiple-Ascending Subcutaneous Doses of DR10624

DR10624 is an Fc fusion protein tri-agonist with balanced GLP-1R/GCGR/FGF21R agonizing activities that complement each other in regulating blood glucose and weight. The GLP-1R agonizing activity lowers blood glucose, GCGR agonizing activity reduces body weight by increasing energy consumption, and FGF21R agonizing activity reduces blood glucose and lipid content. The …

Accepts healthy volunteers
  • 22 Sep, 2022
  • 1 location
Effect of a Mixture of Allium Extracts on LDL Cholesterol Levels Volunteers With Elevated LDL Cholesterol Levels

. Parameters related to metabolic syndrome, cardiovascular health and the immune system will also be analyzed.

Accepts healthy volunteers
  • 08 Jun, 2022
  • 1 location
Congenital Adrenal Hyperplasia Once Daily Hydrocortisone Treatment (CareOnTIME)

, metabolic syndrome, hormonal profile, bone status, quality of life, reproductive, sexual and psychological functions and treatment compliance in patients affected by congenital adrenal hyperplasia due to 21

glucocorticoid therapy
metabolic syndrome
  • 14 Apr, 2022
  • 1 location
Adrenalectomy Versus Follow-up in Patients With Subclinical Cushings Syndrome (AUSC)

study is, that surgery of the adrenal adenoma responsible for the increased secretion of cortisol, will in part cure or ameliorate the metabolic syndrome.

  • 24 Mar, 2022
  • 3 locations
Letrozole in Clomiphene Resistant Infertile Women With Polycystic Ovarian Syndrome

increased risk for infertility, metabolic syndrome, and type 2 diabetes mellitus, and possibly for cardiovascular disease and endometrial carcinoma. Polycystic ovary syndrome is diagnosed in adolescents

cardiovascular disease
polycystic ovary syndrome
endometrial carcinoma
  • 26 May, 2022
  • 1 location
Effect of Baduanjin Exercise on Chronic Periodontal Disease in Elderly

The metabolic syndrome (MetS) is a spectrum of conditions that increase the risk of cardiovascular disease and diabetes mellitus. The components of MetS include dysglycemia, visceral obesity

  • 09 Aug, 2022
  • 1 location
Effect of Weekly GLP1 Agonist Treatment in "Double Diabetes" (TOLEDDO)

Between 16% and 22% of type 1 diabetic patients present a clinical and biological profile of insulin resistance favored by a family history of type 2 diabetes or metabolic syndrome. They

  • 24 Jul, 2022
  • 1 location
Omega-3 PUFA for Treatment of Patients With Idiopathic Oligoasthenoteratospermia

endotoxemia and a series of metabolic syndrome. N-3 polyunsaturated fatty acids may play an important role in regulating metabolism and physiological functions in the body. A clinical research found that both

  • 12 Feb, 2022
  • 1 location