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Found 32 clinical trials
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A Randomized Double Blinded Comparison of Ceftazidime and Meropenem in Severe Melioidosis

treatment regimen. A key question is whether alternative antibiotics could improve early outcome. The hypothesis tested is that meropenem is superior to ceftazidime in terms of mortality for the

  • 5 views
  • 07 Nov, 2020
  • 1 location
None
Evaluating a Novel Individualised Treatment Strategy for Carbapenem-Resistant Gram-Negative Bacteria Infections

Carbapenem-resistant (CR) Gram negative bacteria (GNB) - which are resistant to carbapenems (a last-line potent antibiotic with a high therapeutic index) - are also resistant to all other beta-lactam antibiotics. Most CRGNB are also extensively-drug resistant (XDR) (resistant to all classes of antibiotics except polymyxins and/or tigecycline) or pan-drug resistant …

  • 13 views
  • 18 Oct, 2021
  • 1 location
None
Early Bactericidal Activity of Rifampin + Meropenem + Amoxicillin/Clavulanate in Adults With Pulmonary TB

resistance-conferring rpoB-gene mutations, the combination of meropenem and amoxicillin/clavulanate with rifampin has greater early bactericidal activity (EBA) than the combination of meropenem and

direct microscopy
rifampin
cervical cap
neutrophil count
acid-fast bacilli
  • 16 views
  • 22 Oct, 2021
  • 1 location
None
Efficacy of Extended Infusion of -lactam Antibiotics for the Treatment of Febrile Neutropenia in Hematologic Patients

analyzed are the following: piperacillin-tazobactam, cefepime and meropenem. Half of patients will receive the antibiotic in intermittent infusion, while the other half will receive it in extended infusion

cefepime
neutrophil count
antibiotic therapy
antibiotics
stem cell transplantation
  • 0 views
  • 19 Feb, 2021
  • 1 location
None
Bolus Versus Continuous Infusion of Meropenem

responsible for 70% of drug-resistant infections acquired in the intensive care unit. Meropenem is a -lactam, carbapenem, antibacterial agent usually administered by intermittent infusion. As -lactam efficacy

  • 0 views
  • 27 Jan, 2021
  • 12 locations
None
PipEracillin Tazobactam Versus mERoPENem for Treatment of Bloodstream Infections Caused by Cephalosporin-resistant Enterobacteriaceae (PETERPEN)

comparing treatment with combination beta-lactam-beta-lactamase inhibitor and carbapenems. The investigators aim to evaluate the effect of definitive treatment with meropenem vs. piperacillin-tazobactam on

ceftazidime
cephalosporins
bacteremia
ceftriaxone
carbapenem
  • 23 views
  • 28 Oct, 2021
  • 2 locations
None
A Study to Determine the Efficacy Safety and Tolerability of Aztreonam-Avibactam (ATM-AVI) Metronidazole (MTZ) Versus Meropenem (MER) Colistin (COL) for the Treatment of Serious Infections Due to Gram Negative Bacteria.

A Phase 3 comparative study to determine the efficacy, safety and tolerability of Aztreonam-Avibactam (ATM-AVI) Metronidazole (MTZ) versus Meropenem (MER) Colistin (COL) for the treatment of

colistin
ct scan
antibiotic therapy
antibiotics
meropenem
  • 225 views
  • 30 Nov, 2021
  • 190 locations
None
Safety and Efficacy Study of Cefepime/VNRX-5133 in Patients With Complicated Urinary Tract Infections

This study will assess the safety and efficacy of cefepime/VNRX-5133 compared with meropenem in both eradication of bacteria and in symptomatic response in patients with cUTIs.

meropenem
cefepime
pyelonephritis
acute pyelonephritis
  • 166 views
  • 18 Oct, 2021
  • 103 locations
None
Beta-Lactam InfusioN Group Study

The purpose of this study is to find out whether continuous infusion of beta-lactam antibiotics or intermittent infusion or beta-lactam antibiotics, offers more health advantages to patients or if there is no difference. The investigators will be looking to see whether patients receiving beta-lactams via one administration method or the …

septic shock
mechanical ventilation
antibiotic therapy
beta-lactam
antibiotics
  • 174 views
  • 06 Oct, 2021
  • 104 locations
None
Temocillin vs Meropenem for the Targeted Treatment of Bacteraemia Resistant to Third Gen Cephalosporins

Belgium and UK) vs a carbapenem antibiotic (meropenem) in adults with bacteraemia due to third-generation cephalosporin-resistant Enterobacteriaceae. The duration of treatment will be between 7 and

meropenem
ceftazidime
cephalosporins
ceftriaxone
carbapenem
  • 0 views
  • 20 Oct, 2021
  • 32 locations