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Found 76 clinical trials
PSMA-PET Imaging for Detecting Early Metastatic Prostate Cancer in Men w/ High Decipher Test Scores

This study will enroll 60 patients previously enrolled to MCC#18523, "A Validation Study on the Impact of Decipher® Testing on Treatment Recommendations in African-American and Non-African

metastatic prostate cancer
prostate cancer metastatic
positron emission tomography
prostatectomy
  • 5 views
  • 04 Oct, 2022
  • 1 location
Impact of Time-Restricted Eating on Metabolic and Neuroendocrine Homeostasis, Inflammation and Oxidative Stress in Metabolic Syndrome (TREMNIOS)

12-week self-directed intervention and will log their dietary intake using a smartphone application (myCircadianClock (mCC) app). Glucose homeostasis (blood glucose levels will be monitored

a 12
metabolic syndrome
cholesterol level
antioxidants
blood pressure diastolic
  • 13 views
  • 03 Mar, 2022
  • 1 location
Phase-II Study of Lu177DOTATOC in Adults With STTR(+)Pulmonary Pheochromocytoma Paraganglioma Unknown Primary Thymus NETs (PUTNET) or Any Other Non-.GEP-NET.

Determine the safety and effectiveness of Lu-177 DOTATOC in adult subjects with somatostatin receptor-expressing Pulmonary, Pheochromocytoma, Paraganglioma, Unknown primary, and Thymus neuroendocrine tumors or any other non-.GEP-NET. The treatment regimen will consist of 4 doses of 200 (10%) mCi 177Lu-DOTATOC administered at 8+/- 1-week intervals.

MRI Scan
dotatoc
positron emission tomography/computed tomography
neuroendocrine tumor
fdg pet/ct
  • 0 views
  • 18 Jul, 2021
  • 1 location
The Effectiveness of Online Revised Written Exposure Therapy for PTSD

study will recruit 90 participants, with 60 randomized to the online WET-R group, and 30 randomized to the minimal contact control (MCC) group. The WET-R intervention consists of 5-7 one to one sessions

exposure therapy
  • 0 views
  • 04 Oct, 2022
  • 1 location
Functional Studies of Novel Genes Mutated in Primary Ciliary Dyskinesia II: Genotype to Phenotype

The purpose of this study is to measure mucociliary clearance (MCC) in groups of subjects with the disease Primary Ciliary Dyskinesia (PCD) caused by mutations in different genes. Some of these

  • 0 views
  • 04 Oct, 2022
  • 1 location
Phase II Study Assessing the Effect of BK Specific CTL Lines Generated by Ex Vivo Expansion in Patients With BK Virus Infection and JC Virus Infection

This phase II trial studies how well donor cytotoxic T lymphocytes work in treating patients with malignancies with BK and/or JC virus. Cytotoxic T lymphocytes are made from donated blood cells that are grown in the laboratory and are designed to kill viruses that can cause infections in transplant patients …

prednisone
leflunomide
allogeneic bk-specific cytotoxic t-lymphocytes
HIV Vaccine
cytotoxic chemotherapy
  • 60 views
  • 28 Oct, 2022
  • 1 location
NBTXR3 Activated by Radiotherapy for Patients With Advanced Cancers Treated With An Anti-PD-1 Therapy

The 1100 study is an open-label, Phase I, dose escalation and expansion prospective clinical study to assess the safety of intratumoral injection of NBTXR3 activated by radiotherapy in combination with anti-PD-1 therapy.

pembrolizumab
cancer
nbtxr3
nivolumab
  • 13 views
  • 07 Oct, 2022
  • 7 locations
A Clinical Trial Assessing BT-001 Alone and in Combination With Pembrolizumab in Metastatic or Advanced Solid Tumors

This is a Phase I/IIa, multicenter, open-label, consecutive cohorts, dose-escalation study of BT-001 with repeated IT administrations alone and in combination with IV infusions of pembrolizumab.

pembrolizumab
breast cancer
carcinoma
sargramostim
metastatic sarcoma
  • 0 views
  • 04 Oct, 2022
  • 5 locations
A Phase I Study of Pomalidomide and Nivolumab in Patients With Virus-Associated Malignancies With or Without HIV

, hepatocellular carcinoma, head and neck cancer, nasopharyngeal carcinoma, gastric cancer, anal cancer, cervical cancer, vaginal cancer, vulvar cancer, penile cancer, Merkel cell carcinoma, Kaposi sarcoma, and

carcinoma
combination chemotherapy
cytotoxic chemotherapy
cancer chemotherapy
aspirin
  • 0 views
  • 21 Oct, 2022
  • 1 location
Study of MEM-288 Oncolytic Virus in Solid Tumors Including Non-Small Cell Lung Cancer (NSCLC)

This phase I trial is designed as an open-label, dose escalation trial of MEM-288 monotherapy in which investigators aim to find the maximum tolerated dose (MTD) and recommended phase II dose (RP2D). Subjects with selected solid tumors including non-small cell lung cancer (NSCLC) who have a tumor lesion which is …

tyrosine
KRAS
cytotoxic t-lymphocyte antigen 4
cancer chemotherapy
kinase inhibitor
  • 0 views
  • 10 Jul, 2022
  • 2 locations