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Found 1253 clinical trials
Dopaminergic Enhancement of Learning and Memory in Healthy Adults and Patients With Dementia/Mild Cognitive Impairment

This study aims to determine whether levodopa is effective in boosting learning and memory in healthy subjects and patients with dementia or Mild Cognitive Impairment. We also examine in

mild cognitive impairment
cognitive impairment
  • 07 Nov, 2020
  • 1 location
Neurocognitive Dysfunction After Anesthesia in Patients With Recent Concussion

Researchers are trying to determine if the impact of a concussion on the brain is affected by anesthesia and surgery.

  • 25 Jan, 2021
  • 1 location
Standardization and Optimization of TMS Protocols for the Treatment of PD With Depression or Cognitive Impairment

The goal of this study is to determine whether transcranial magnetic stimulation (TMS) is an effective treatment in Parkinson's disease patients with depression or cognitive impairment. The

  • 31 Jan, 2021
  • 10 locations
Clinical and Biological Effects of Citrus-phytochemicals in Subjective Cognitive Decline.

Subjective cognitive decline (SCD) is receiving increasing attention as a risk factor for incident dementia due to AD. SCD manifests prior to the onset of clinical impairment, and as such could

  • 05 May, 2021
  • 1 location
Potential Role of Acupuncture Treatment in Neuronal and Network Dysfunction in Patients With Vascular Cognitive Impairment

Vascular cognitive impairment (VCI) is a broad dimensional term, ranging from mild cognitive impairment without incapacity on activity of daily living to vascular dementia (VaD), referred to as

  • 23 Jan, 2021
  • 1 location
Impact of a Cognitive Intervention Enriched With Leisure Activities in Persons With Subjective Cognitive Decline

activities. This will be done with a partially randomized controlled double-blind preference trial with a comprehensive cohort design, in participants with subjective cognitive decline (SCD) recruited in

  • 05 Feb, 2021
  • 2 locations
Memantine for the Treatment of Cognitive Impairment in Systemic Lupus Erythematosus

A phenome-wide association study (PheWAS) identified an association between a variant in the human gene for the N2A subunit of the N-methyl-D-aspartate (NMDA) receptor, GRIN2A, and Systemic Lupus Erythematosus (SLE). A single nucleotide polymorphism (SNP) in this gene encodes for increased NMDA receptor activity. Based on the potential function of …

  • 01 May, 2021
  • 1 location
Effect of Donepezil on the Reorganization of Cognitive Neural Network in Patients With Post-Stroke Cognitive Impairment

The purpose of this study is to demonstrate the efficacy and safety of donepezil on the recovery of cognitive function in patients with stroke and to delineate the neurophysiologic mechanisms of the therapeutic effect of donepezil on the recovery of cognitive network using functional neuroimaging technique.

mini-mental state examination
ischemic stroke
  • 07 Nov, 2020
  • 1 location
Memory and Antioxidants in Vascular Impairment Trial

This is a 24-week randomized, double-blind, placebo-controlled parallel group design study involving Vascular cognitive impairment-no dementia (VCIND) patients to evaluate the efficacy and

  • 26 Mar, 2021
  • 1 location
Evaluation of a Cognitive Remediation Program for Mood Disorders

Psychotherapeutic management of cognitive disorders in patients suffering from a mood disorder

  • 25 Jan, 2021
  • 1 location