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Found 1328 clinical trials
COG-REAGENT: COGnitive tRaining in patiEnts With Amnestic Mild coGnitive impairmENT

This study evaluates the efficacy and mechanism of internet-based cognitive training in patients with amnestic mild cognitive impairment (aMCI). Half of participants will receive multi-domain

  • 16 Apr, 2021
  • 1 location
Evaluation of Safety of Contraloid Acetate in Patients With Mild Cognitive Impairment Due to Alzheimer's Disease

Patients with mild cognitive impairment due to Alzheimer's disease (MCI due to AD) are at high risk to develop Alzheimers dementia. The therapeutic agent Contraloid has the potential to

  • 02 May, 2021
  • 1 location
Dopaminergic Enhancement of Learning and Memory in Healthy Adults and Patients With Dementia/Mild Cognitive Impairment

This study aims to determine whether levodopa is effective in boosting learning and memory in healthy subjects and patients with dementia or Mild Cognitive Impairment. We also examine in

mild cognitive impairment
cognitive impairment
  • 07 Nov, 2020
  • 1 location
Neurocognitive Dysfunction After Anesthesia in Patients With Recent Concussion

Researchers are trying to determine if the impact of a concussion on the brain is affected by anesthesia and surgery.

  • 28 Aug, 2021
  • 1 location
Safety and Efficacy of Maraviroc in Post-stroke Cognitive Impairment

Hypotheses: 1. Subjects with mild post-stroke cognitive impairment (PSCI) are at risk of developing vascular dementia (VaD). Maraviroc treatment in patients suffering from mild PSCI will halt

  • 27 Jul, 2021
  • 1 location
Memantine for the Treatment of Cognitive Impairment in Systemic Lupus Erythematosus

A phenome-wide association study (PheWAS) identified an association between a variant in the human gene for the N2A subunit of the N-methyl-D-aspartate (NMDA) receptor, GRIN2A, and Systemic Lupus Erythematosus (SLE). A single nucleotide polymorphism (SNP) in this gene encodes for increased NMDA receptor activity. Based on the potential function of …

  • 01 May, 2021
  • 1 location
Standardization and Optimization of TMS Protocols for the Treatment of PD With Depression or Cognitive Impairment

The goal of this study is to determine whether transcranial magnetic stimulation (TMS) is an effective treatment in Parkinson's disease patients with depression or cognitive impairment. The

  • 31 Jan, 2021
  • 10 locations
Clinical and Biological Effects of Citrus-phytochemicals in Subjective Cognitive Decline.

Subjective cognitive decline (SCD) is receiving increasing attention as a risk factor for incident dementia due to AD. SCD manifests prior to the onset of clinical impairment, and as such could

  • 10 May, 2021
  • 1 location
Potential Role of Acupuncture Treatment in Neuronal and Network Dysfunction in Patients With Vascular Cognitive Impairment

Vascular cognitive impairment (VCI) is a broad dimensional term, ranging from mild cognitive impairment without incapacity on activity of daily living to vascular dementia (VaD), referred to as

  • 23 Jan, 2021
  • 1 location
DEMA-Pro Intervention for Seniors With Subjective Cognitive Decline and Living at Home

cognitive decline (SCD), an early clinical sign of Alzheimer's disease and related dementia. SCD is associated with diminished activity performance, poor quality-of-life and other adverse health outcomes

  • 07 Sep, 2021
  • 1 location