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Found 61 clinical trials
Featured trial
A Phase 3 Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Aducanumab (BIIB037) in Subjects With Early Alzheimer's Disease

A Phase 3 Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Aducanumab (BIIB037) in Subjects With Early Alzheimer's Disease

  • 68 views
  • 08 Dec, 2020
  • 1 location
Featured trial
A Randomized, Double-Blinded, Placebo-Controlled Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB037 in Subjects With Prodromal or Mild Alzheimer's Disease

A Randomized, Double-Blinded, Placebo-Controlled Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB037 in Subjects With Prodromal or Mild Alzheimer's Disease

  • 87 views
  • 25 Mar, 2021
  • 1 location
Multi-omics Research of Idopathic Normal Pressure Hydrocephalus (iNPH)

The research is designed to study the prognostic factors of ventriculoperitoneal (VP) shunt for iNPH by multi-omics research

  • 0 views
  • 18 Aug, 2021
  • 1 location
Impact of Von Willebrand Factor-platelet Aggregates in Patients With Type 2B Disease

The working hypothesis is that patients with Von Willebrand Disease-type 2B may have neurological symptoms due to the chronic formation of platelets/Von Willebrand Factor aggregates. Interestingly, several patients present nonspecific neurological symptoms (nystagmus, headaches, memory disorder, ) which may be associated with cerebral microangiopathy and chronic microvessel inflammation secondary to …

  • 5 views
  • 25 Aug, 2021
  • 1 location
The Effect of Repetitive Transcranial Magnetic Stimulation on the Cognition in People With Parkinson's Disease

Parkinson's disease (PD) is the second most common neurodegenerative disease. The cardinal symptoms of PD are tremor, rigidity, bradykinesia and postural instability. Cognitive impairment and dementia are also one of the key features of the non-motor symptoms of PD. At present, the mainstream treatment of PD-dementia is the dopaminergic rivastigmine. …

  • 0 views
  • 13 Apr, 2021
  • 1 location
Repetitive Transcranial Magnetic Stimulation on Freezing of Gait in People With Parkinson's Disease

Parkinson's disease (PD) is the second most common neurodegenerative disease. The cardinal symptoms of PD are tremor, rigidity, bradykinesia and postural instability. Gait disturbance is also one of the key features of PD. At present, the mainstream treatment of PD is the dopaminergic supplement. However, the response to the medical …

  • 0 views
  • 11 Apr, 2021
  • 1 location
Improving Physical Activity of Older People in Community Through Trained Volunteers: the ImPACt Study

Research question is can volunteers be trained to deliver an exercise programme for community-dwelling older people attending community clubs and is the intervention acceptable to older people and volunteers? Physical activity is important for older adults and studies have shown the benefits of physical activity on health outcomes including maintenance …

Accepts healthy volunteers
  • 0 views
  • 10 Oct, 2021
  • 1 location
Blinded Randomized Trial of Anticoagulation to Prevent Ischemic Stroke and Neurocognitive Impairment in AF (BRAIN-AF)

This is a prospective, multicenter, randomized, double-blinded clinical trial exploring the efficacy and safety of rivaroxaban as compared to standard of care in reducing stroke, transient ischemic attack (TIA) and neurocognitive decline, in subjects with non-valvular AF and with low risk of stroke.

hypertension
diabetes
fibrillation
heart failure
holter monitor
  • 8 views
  • 22 Jan, 2022
  • 1 location
Time Window for Ischemic Stroke First Mobilization Effectiveness (TIME)

Early mobilization was thought to be effective in patients with acute ischemic stroke. As the essential component of stroke unit care, early mobilization has already been part of routine clinical practice. However, it is uncertain that which and when medical service focusing on functional recovery should be delivered after the …

stroke
  • 0 views
  • 27 Apr, 2022
  • 1 location
The Swedish BioFINDER 2 Study (BioFINDER2)

The Swedish BioFINDER 2 study is a new study that will launch in 2017 and extends the previous cohorts of BioFINDER 1 study (www.biofinder.se). BioFINDER 1 is used e.g. to characterize the role of beta-amyloid pathology in early diagnosis of Alzheimer's disease (AD) using amyloid-PET (18F-Flutemetamol) and A analysis in …

neurodegenerative disorder
cognitive impairment
brain imaging
mild cognitive impairment
parkinson's disease
  • 176 views
  • 25 Feb, 2022
  • 1 location