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Found 52 clinical trials
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A Washington University research study seeks participants 65 years of age and older.

A Washington University research study seeks participants 65 years of age and older.

  • 232 views
  • 23 Nov, 2020
  • 1 location
featured
A Phase 3 Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Aducanumab (BIIB037) in Subjects With Early Alzheimer's Disease

A Phase 3 Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Aducanumab (BIIB037) in Subjects With Early Alzheimer's Disease

  • 62 views
  • 08 Dec, 2020
  • 1 location
featured
A Randomized, Double-Blinded, Placebo-Controlled Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB037 in Subjects With Prodromal or Mild Alzheimer's Disease

A Randomized, Double-Blinded, Placebo-Controlled Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB037 in Subjects With Prodromal or Mild Alzheimer's Disease

  • 82 views
  • 08 Dec, 2020
  • 1 location
Ketamine vs Midazolam on Cognitive Function in Elderly in Elective Surgery Three-Months Postoperatively (ketaminvsMDZ)

the patient in the postoperative period, through tests such as the Mini Mental State Examination. sub-anesthetic doses of ketamine have been recently proposed to reduce the postoperative markers of

mini-mental state examination
cognitive changes
delirium
dementia
postoperative cognitive dysfunction
  • 0 views
  • 24 Jan, 2021
  • 1 location
Bicycle Simulator Training in Older Adults: A Randomized Controlled Trial

A Randomized Control Trial will be conducted with Independent old adults (age 70 years old and older) who willing to participate in the study. They will be randomly allocated to two groups: 1) Stationary bicycle riding that includes perturbation balance training during riding; 2) Stationary bicycle riding that does not …

balance training
  • 0 views
  • 24 Jan, 2021
  • 1 location
Blinded Randomized Trial of Anticoagulation to Prevent Ischemic Stroke and Neurocognitive Impairment in AF

This is a prospective, multicenter, randomized, double-blinded clinical trial exploring the efficacy and safety of rivaroxaban as compared to standard of care in reducing stroke, transient ischemic attack (TIA) and neurocognitive decline, in subjects with non-valvular AF and with low risk of stroke.

stroke
rivaroxaban
heart failure
transient ischemic attack
electrocardiogram
  • 8 views
  • 24 Jan, 2021
  • 1 location
Promoting Health LongevIty Through Mitigation and Prevention of Frailty in Community-dwelling Elderly (Pro-LIFE)

The current healthcare response to frailty has been mainly reactive to acute health crises of the elderly. With its insidious onset and progression, frailty is often not apparent unless actively sought. Well-validated models of frailty already exist and, instead of trying to create new frailty criteria or insisting on a …

  • 0 views
  • 14 Dec, 2020
  • 1 location
The Swedish BioFINDER 2 Study

The Swedish BioFINDER 2 study is a new study that will launch in 2017 and extends the previous cohorts of BioFINDER 1 study (www.biofinder.se). BioFINDER 1 is used e.g. to characterize the role of beta-amyloid pathology in early diagnosis of Alzheimer's disease (AD) using amyloid-PET (18F-Flutemetamol) and A analysis in …

mini-mental state examination
dementia, frontotemporal
neurodegenerative disorder
major neurocognitive disorder
early diagnosis
  • 165 views
  • 22 Jan, 2021
  • 2 locations
Study of AGB101 in Mild Cognitive Impairment Due to Alzheimer's Disease

placebo or AGB101 (220 mg), once daily for 78 weeks. Secondary objectives are to assess the effect of AGB101 compared with placebo on clinical progression as measured by Mini-Mental State Examination

mini-mental state examination
cholinesterase
cholinesterase inhibitors
antidepressants
apolipoprotein e
  • 111 views
  • 25 Jan, 2021
  • 32 locations
Combined Lumbosacral Nerve Block Versus Spinal Anesthesia for Cognitive Function After Hip Prothesis

pre- and postoperatively, using the Mini Mental State Examination (MMSE). The presence of CD will be determined at follow-up evaluation up to three months after surgery.

mini-mental state examination
delirium
cognitive decline
mental state examination
vasopressor drugs
  • 1 views
  • 19 Jan, 2021
  • 1 location