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Found 56 clinical trials
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A Phase 3 Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Aducanumab (BIIB037) in Subjects With Early Alzheimer's Disease

A Phase 3 Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Aducanumab (BIIB037) in Subjects With Early Alzheimer's Disease

  • 62 views
  • 08 Dec, 2020
  • 1 location
featured
A Washington University research study seeks participants 65 years of age and older.

A Washington University research study seeks participants 65 years of age and older.

  • 232 views
  • 23 Nov, 2020
  • 1 location
featured
A Randomized, Double-Blinded, Placebo-Controlled Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB037 in Subjects With Prodromal or Mild Alzheimer's Disease

A Randomized, Double-Blinded, Placebo-Controlled Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB037 in Subjects With Prodromal or Mild Alzheimer's Disease

  • 82 views
  • 25 Mar, 2021
  • 1 location
The Effect of Repetitive Transcranial Magnetic Stimulation on the Cognition in People With Parkinson's Disease

Parkinson's disease (PD) is the second most common neurodegenerative disease. The cardinal symptoms of PD are tremor, rigidity, bradykinesia and postural instability. Cognitive impairment and dementia are also one of the key features of the non-motor symptoms of PD. At present, the mainstream treatment of PD-dementia is the dopaminergic rivastigmine. …

  • 0 views
  • 13 Apr, 2021
  • 1 location
Repetitive Transcranial Magnetic Stimulation on Freezing of Gait in People With Parkinson's Disease

Parkinson's disease (PD) is the second most common neurodegenerative disease. The cardinal symptoms of PD are tremor, rigidity, bradykinesia and postural instability. Gait disturbance is also one of the key features of PD. At present, the mainstream treatment of PD is the dopaminergic supplement. However, the response to the medical …

  • 0 views
  • 11 Apr, 2021
  • 1 location
Blinded Randomized Trial of Anticoagulation to Prevent Ischemic Stroke and Neurocognitive Impairment in AF

This is a prospective, multicenter, randomized, double-blinded clinical trial exploring the efficacy and safety of rivaroxaban as compared to standard of care in reducing stroke, transient ischemic attack (TIA) and neurocognitive decline, in subjects with non-valvular AF and with low risk of stroke.

ejection fraction
12 lead ECG
stroke
rivaroxaban
diabetes
  • 8 views
  • 26 Feb, 2021
  • 1 location
Time Window for Ischemic Stroke First Mobilization Effectiveness

Early mobilization was thought to be effective in patients with acute ischemic stroke. As the essential component of stroke unit care, early mobilization has already been part of routine clinical practice. However, it is uncertain that which and when medical service focusing on functional recovery should be delivered after the …

stroke
  • 0 views
  • 21 Mar, 2021
  • 1 location
The Swedish BioFINDER 2 Study

The Swedish BioFINDER 2 study is a new study that will launch in 2017 and extends the previous cohorts of BioFINDER 1 study (www.biofinder.se). BioFINDER 1 is used e.g. to characterize the role of beta-amyloid pathology in early diagnosis of Alzheimer's disease (AD) using amyloid-PET (18F-Flutemetamol) and A analysis in …

neurodegenerative disorder
neurodegenerative diseases
mini-mental state examination
early diagnosis
cognitive impairment
  • 165 views
  • 11 Mar, 2021
  • 3 locations
Ketamine vs Midazolam on Cognitive Function in Elderly in Elective Surgery Three-Months Postoperatively (ketaminvsMDZ)

the patient in the postoperative period, through tests such as the Mini Mental State Examination. sub-anesthetic doses of ketamine have been recently proposed to reduce the postoperative markers of

mini-mental state examination
mental state examination
dementia
postoperative cognitive dysfunction
antidepressants
  • 0 views
  • 28 Jan, 2021
  • 1 location
Exploring the Utility of [18F]3F4AP for Demyelination Imaging in Controls Neurodegeneration and Traumatic Brian Injury

with neuropsychological testing in people with TBI and AD/MCI. Hypothesis 5A: increased PET signal (VT or SUV) will correlate with impaired Mini Mental State Examination (MMSE).

  • 0 views
  • 29 Apr, 2021
  • 1 location