Found 6251 clinical trials
Use of a Non-Invasive Brainstem Neuromodulation Device to Improve Neurovascular Status in Parkinson's Disease
This study is a single-site, double-blinded, randomized clinical trial designed to elucidate mechanism(s) of action for symptomatic benefits observed in Parkinson's disease (PD)
- 31 views
- 04 Oct, 2022
- 1 location
A Study of TAK-341 in Treatment of Multiple System Atrophy
The main aim is to see how TAK-341 works after 52 weeks in participants with multiple system atrophy as measured by the Unified Multiple System Atrophy Rating Scale Part I (UMSARS). The study will enroll approximately 138 patients. Participants will receive a total of 13 intravenous infusions every 4 weeks …
- 34 views
- 07 Apr, 2023
- 1 location
Methodology Issues in a Tailored Light Treatment for Persons With Dementia
Tailored light treatment will increase sleep efficiency, reduce depression and reduce agitation scores in those with Alzheimer's disease and related dementia
- 13 views
- 24 Mar, 2023
- 2 locations
Safety and Target Engagement of Centella Asiatica in Cognitive Impairment
This clinical trial is focused on determining how a 6 week oral administration of a water extract of the herb Centella asiatica affects processes in the brain or body that are associated with memory loss, in comparison with a placebo. This study will also assess the safety and tolerability of …
- 3 views
- 22 May, 2023
- 1 location
A Ten-Week Online Acceptance and Commitment Therapy Intervention for Family Caregivers of People With Dementia
We are conducting a research project to evaluate if coach-guided videoconferencing acceptanceand commitment therapy (ACT) is effective for improving psychological health in familycaregivers of people with dementia. You may qualify for the study if you are adults (age 18 orover) who are currently taking the primary responsibility for the care …
- 67 views
- 11 Apr, 2023
- 1 location
Electronic Memory and Management Aid (EMMA)
This study will evaluate the effectiveness of a personalized, web-based training intervention that was developed to teach use of an Electronic Memory and Management Aid (EMMA) application. The app-based system is designed to support everyday memory, daily activity management and positive health behavior engagement for older adults with subjective cognitive …
- 0 views
- 09 Feb, 2023
- 1 location
- 1186 views
- 23 Nov, 2020
- 1 location
A Phase 2, Double-Blind, Dose-Ranging, Placebo-Controlled Study With Open-Label Extension to Evaluate the Safety and Efficacy of Itacitinib in Moderate to Severe Ulcerative Colitis
double-blind, randomized, placebo-controlled treatment periods followed by 40 weeks open label extension period.
- 78 views
- 10 May, 2022
- 5 locations
A Multicenter, Randomized, Double-Blind, Placebo-Controlled 12-Week Study To Evaluate The Safety And Efficacy Of Oral Difelikefalin In Advanced Chronic Kidney Disease Subjects With Moderate-To-Severe Pruritus And Not On Dialysis With An Up To 52-Week Long-Term Extension
the results of a planned interim assessment conducted when approximately 50% of the planned 400 subjects have been randomized and have either completed the 12-week Treatment Period 1 or have
- 0 views
- 29 Sep, 2022
- 1 location
A PATIENT- AND INVESTIGATOR-BLIND, PLACEBOCONTROLLED STUDY TO EVALUATE THE EFFICACY, SAFETY, AND TOLERABILITY OF BEPRANEMAB (UCB0107) IN STUDY PARTICIPANTS WITH PRODROMAL TO MILD ALZHEIMER’S DISEASE (AD), FOLLOWED BY AN OPENLABEL EXTENSION PERIOD
Bepranemab (UCB0107) is being developed with the aim of blocking or reducing the cell-to-cell spread of tau pathology in patients with tau-mediated diseases, such as AD. To date, single ascending doses of bepranemab (up to 120mg/kg) have been evaluated in healthy study participants in two Phase 1 studies and no …
- 14 views
- 24 Jun, 2022
- 1 location