Found 6273 clinical trials
Evaluating the Psychometric Properties of Three Clinical Trial Outcome Measures for Rett Syndrome
> The study consists of two components: a virtual research visit with our research team via Zoom and two, in-home collection periods using wearable technology. The virtual research visit will last
- 230 views
- 30 Jun, 2022
- 1 location
- Online study
Microbiome in aging gut and brain (MiaGB) study
The Microbiome in aging of Gut and Brain study aims to determine how the microbiome impacts our brain health during aging continuum, and how our dietary habits are linked with it. In this study, we plan to recruit 60 years or older subjects with normal cognition, mild cognitive impairment (MCI) …
- 335 views
- 09 Feb, 2023
- 1 location
- Online study
Real-World Compensatory Strategy Use
Older adults often spontaneously utilize compensatory strategies, or behaviors intended to make up for or work around a perceived deficit, to support successful completion of daily activities. In this study, we aim to enhance understanding of everyday functioning and compensatory strategy use in aging adults. Data collected will be used …
- 410 views
- 13 Mar, 2023
- 1 location
- Online study
A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Dose Ranging Study of the Efficacy and Safety of INCB054707 in Participants With Prurigo Nodularis
The purpose of this study is to evaluate the efficacy and safety of INCB054707 in participants with prurigo nodularis over a 16-week double-blind placebo-controlled treatment period, followed by
- 16 views
- 28 Oct, 2022
- 32 locations
Study of the Efficacy and Safety of Parsaclisib in Participants With Primary Warm Autoimmune Hemolytic Anemia (PATHWAY) (PATHWAY)
The purpose of this study is to evaluate the efficacy and safety of parsaclisib compared with placebo in participants with Primary Warm Autoimmune Hemolytic Anemia (wAIHA),
- 11 views
- 11 Nov, 2022
- 39 locations
A Trial Evaluating Different Dosing Durations of TEPEZZA® Treatment in Patients with Thyroid Eye Disease (TED)
The overall objective is to investigate the safety, tolerability and need for re-treatment of 3 different TEPEZZA® treatment durations (4, 8, or 16 infusions) in patients with TED.
- 29 views
- 13 Oct, 2022
- 14 locations
Dupilumab in Allergic Fungal Rhinosinusitis (AFRS) (LIBERTY-AFRS-AI)
Primary Objective: To evaluate the ability of dupilumab to reduce the need for rescue therapy with systemic corticosteroids (SCS) or surgery of AFRS in patients with AFRS who previously have had sino-nasal surgery Secondary Objectives: To evaluate the efficacy of treatment with dupilumab to reduce sinus opacification in a population …
- 123 views
- 31 Mar, 2023
- 5 locations
Assessment of Safety, Tolerability, and Efficacy Measured by Amyloid Reduction of LY3372993 in Early Symptomatic Alzheimer's Disease
The reason for this study is to collect safety and efficacy information regarding the study drug remternetug in participants with early Alzheimer's disease (AD).
- 19 views
- 15 Dec, 2022
- 75 locations
A trial evaluating TEPEZZA® in Patients With Diffuse Cutaneous Systemic Sclerosis (dcSSc)
The overall objective is to investigate the safety, tolerability and effect on insulin-like growth factor-1 (IGF-1), inflammatory and fibrotic biomarkers of TEPEZZA® administered once every 3 weeks (q3W) for 24 weeks in the treatment of participants with diffuse cutaneous systemic sclerosis (dcSSc).
- 6 views
- 11 Aug, 2022
- 5 locations
A Study of TAK-341 in Treatment of Multiple System Atrophy
The main aim is to see how TAK-341 works after 52 weeks in participants with multiple system atrophy as measured by the Unified Multiple System Atrophy Rating Scale Part I (UMSARS). The study will enroll approximately 138 patients. Participants will receive a total of 13 intravenous infusions every 4 weeks …
- 29 views
- 14 Dec, 2022
- 1 location