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Found 301 clinical trials
Dual Task Gait Performance in Pediatric Oncology Patients

Cancer incidence, which is recognized as the leading cause of death in children worldwide, is gradually increasing. Most studies on children who survive cancer show that the disease and its treatment have side effects and long-term late effects on the musculoskeletal system, physical function, gait and cognitive skills. Therefore, dual …

  • 0 views
  • 13 Mar, 2021
  • 1 location
SSRI's and the Rate of Progression From MCI to Dementia

This trial is investigating if serotonin reuptake inhibitor (SSRI) use in Mild Cognitive Impairment (MCI) patients will lead to a lower rate of progression to dementia. It's hypothesized that patients treated with an SSRI at the time of MCI diagnosis, without evidence of an active primary psychiatric condition other than …

mild cognitive impairment
dementia
cognitive impairment
alzheimer's disease
  • 0 views
  • 25 Jan, 2022
  • 1 location
Performances on Cognitive Functions and Brain Function and Follow-up After Different Treatments in Patients With Autonomous Cortisol Secretion: a Single-center, Prospective, Observational Study

This is a single center, prospective, observational study to explore and evaluate the differences on cognitive function and brain function by functional-MRI in autonomous cortisol secretion patients, and the different treatments methods on the cognitive function and brain function in patients with autonomous cortisol secretion

Accepts healthy volunteers
  • 0 views
  • 12 May, 2022
Pilot Study of NeuroTriage Device in Patients With Potential Brain Injury and/or Impairment

This protocol is aimed at collecting oculomotor response data from a variety of brain injuries and impairments, and to secondarily evaluate the functionality and ease of use of the NeuroTriage device in the ED in patients with any presumed brain injury and/or impairment. For example, prior studies in adolescents with …

multiple trauma
post-concussion syndrome
amnesia
confusion
concussion
  • 121 views
  • 01 Feb, 2022
  • 1 location
Study for the Evaluation of the Feasibility of Applying Advanced MRI Scanning in Pediatric Clinical Practice

The purpose of this research study is to evaluate the feasibility in conducting advanced MRI sequences in a pediatric clinical setting. The study will be observational in nature, and will only evaluate the studies of pediatric patients who have already been prescribed an advanced MRI for clinical neurological purposes. The …

5 minute
  • 0 views
  • 23 Feb, 2022
  • 1 location
Amyloid and Glucose PET Imaging in Alzheimer and Vascular Cognitive Impairment Patients With Significant White Matter Disease (MITNEC C6)

The prevalence of both Alzheimer's Disease (AD) and stroke doubles each decade over 65 years old. Both are major causes of dementia, currently estimated to affect 46 million people worldwide. The current costs globally are $818 billion. Additionally, in population studies elders over 65 years, "covert" cerebral small vessel disease …

cognitive decline
positron emission tomography
dementia
mini-mental state examination
cognitive impairment
  • 98 views
  • 12 May, 2022
  • 7 locations
Brain Network Activation and Gait and Posture in FXTAS (FXTAS-BNA)

In this study the investigators aim to identify and characterize a potential neurophysiological biomarker by mapping functional networks of brain activity (Brain Network Activation, BNA) based on analysis of evoked response potential (ERP) signals in both asymptomatic FMR1 premutation carriers and in patients with various stages of FXTAS. Additionally correlations …

  • 20 views
  • 27 Jan, 2022
  • 1 location
Cerebrovascular Reactivity in Alzheimer's Disease (VARAD-ET)

The etiology of Alzheimer's disease (AD), the most common type of dementia, remains largely undefined and the early diagnostic and effective treatments are still not available. In addition to the neuropathological hallmarks, cerebrovascular dysfunction has been identified as an important component of AD. Using the experimental models, we showed that …

neuropsychological test
dementia
cognitive impairment
alzheimer's disease
  • 1 views
  • 24 Feb, 2022
  • 1 location
Atlas of Retinal Imaging in Alzheimer's Study (ARIAS)

The Atlas of Retinal Imaging in Alzheimer's (ARIAS) study is a 5-year study examining the natural history of retinal imaging biomarkers associated with disease risk, disease burden, and disease progression in Alzheimer's disease (AD). The objective of this project is to create a 'gold standard' reference database of structural anatomic …

eye exam
positron emission tomography
dementia
cognitive assessment
cognitive impairment
  • 0 views
  • 25 Jan, 2022
  • 3 locations
Functional Near Infrared Spectroscopy in Adult Cardiac Surgery

Brain injury is a serious problem after cardiac surgery. Brain injury can become evident in the form of stroke and cognitive dysfunction after surgery. The current neuromonitoring technique used is unable to monitor the region of the brain that is most susceptible to injury. This study aims to use a …

stroke
  • 0 views
  • 24 Feb, 2021
  • 1 location