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Found 77 clinical trials
The Role of the Circadian System in Binge Eating Disorder

Binge eating disorder (BED) shows prominent circadian features that suggest a delay in circadian phase, and preliminary evidence shows binge eating may be responsive to chronobiological interventions, implicating a circadian system dysfunction in its pathophysiology. What remains lacking, however, is comprehensive knowledge of the characteristics of circadian system dysfunction in …

Accepts healthy volunteers
  • 23 Mar, 2022
  • 1 location
The Circadian Rhythm of ICU Patients With Acute Myocardial Infraction and the Effect of Light Therapy

By using subjective and objective measurements, the investigators monitore the change of circadian rhythm in Intensive Care Unit (ICU) patients with acute myocardial infarction and the effect of light therapy.

  • 19 Jul, 2021
  • 1 location
The Effects of Milk and Banana Given as a Night Meal to Individuals Diagnosed With Sleep Disorders on Sleep Quality, BDNF and Appetite Mechanism (diet)

The aim of this study to determine the impact of banana and milk on sleep and appetite

body mass index
primary insomnia
sleep disorder
  • 23 Sep, 2022
  • 1 location
Racial Differences in Circadian and Sleep Mechanisms for Nicotine Dependence, Craving, and Withdrawal

The number one preventable cause of death in the world is tobacco use. Cigarette smoking in particular, costs an estimated $300 billion due to expenses related to medical care and lost productivity. Despite similar smoking prevalence rates, blacks suffer disproportionately from smoking-related harms compared to whites.Sleep disparities such as shortened …

cigarette smoke
tobacco smoke
poor sleep
smoking cessation therapy
withdrawal symptoms
  • 19 Jun, 2022
  • 1 location
Bright Light Exposure in Critical Ill Patients

Elucidate the influence of intense light therapy pretreatment in patients undergoing cardiac surgery. We hypothesize that intense light exposure is associated with the peripheral stabilization of Per2 in human buccal swabs and plasma samples before surgery and with a decrease of Troponin I levels after surgery. In addition, we hypothesize …

heart surgery
troponin i
  • 16 May, 2022
  • 1 location
Suvorexant and Sleep/Delirium in ICU Patients

Investigators will evaluate the efficacy of postoperative oral suvorexant treatment on nighttime wakefulness after persistent sleep onset (WASO) among adult cardiac surgical patients recovering in the cardiac intensive care unit (ICU). The study include patients ≥ 60 years old undergoing coronary artery bypass graft surgery (CABG), with or without valve …

coronary artery bypass
wake after sleep onset
  • 04 Jun, 2022
  • 1 location
Digital CBTI for Comorbid Insomnia in Chronic Migraine

The overall aims of the study are: Aim 1: Estimate effect sizes: To estimate the effects of dCBT-I on insomnia symptoms compared to a control group (sleep hygiene education) and estimate the relationship between changes in insomnia symptoms and the reduction in migraines. Aim 2: Explore mechanisms of change: To …

chronic migraine
  • 25 Mar, 2022
  • 1 location
Sleep in Psychiatric Care (SIP): A Transdiagnostic Group-based Sleep-school as Treatment for Comorbid Insomnia

Sleep disorders commonly co-occur with psychiatric disorders. Sleep disorders are often treated with medication or not at all in psychiatric care, although there exist a plethora of documentation of the effectiveness of sleep interventions. There is also an increase in studies showing effectiveness of sleep-interventions when the sleep disorder co-occurs …

  • 30 Dec, 2021
  • 1 location
Light and the Effect on Metabolic Syndrome and Alzheimer's Disease

This study's main hypothesis is that a delivering a tailored lighting intervention (TLI) will provide a successful means for promoting circadian entrainment and treating metabolic disease and inflammation in patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD) and Alzheimer's disease and related dementias (ADRD). As such, the proposed …

alzheimer's disease
mild cognitive impairment
metabolic syndrome
  • 12 May, 2022
  • 3 locations
Behavioral Chronotype: Impact on Sleep and Metabolism

The purpose of this study is to examine how the timing of eating changes how the body makes and uses energy (metabolism). This study will also examine if metabolism changes with age.

Accepts healthy volunteers
  • 21 Mar, 2022
  • 1 location