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Found 261 clinical trials
Rhenium-Skin Cancer Therapy (SCT) for the Treatment of Non-Melanoma Skin Cancer. (EPIC-Skin)

Efficacy of Personalised Irradiation with Rhenium-Skin Cancer Therapy (SCT) for the treatment of non-melanoma skin cancer; a phase IV multi-centre, international, open label, single arm study

  • 2 views
  • 20 Apr, 2022
  • 2 locations
Study of Ruxolitinib in Solid Organ Transplant Recipients With Advanced Cutaneous Squamous Cell Carcinoma

In this open-label, multicenter, Phase II study, the investigators propose to evaluate the efficacy of ruxolitinib, an orally administered inhibitor of JAK1/2, in solid organ transplant recipients with advanced cSCC. In a safety lead-in of 6 patients, subjects will receive ruxolitinib 15mg twice daily (BID). After 4 weeks, if dose-limiting …

  • 0 views
  • 04 Oct, 2022
  • 2 locations
Nemvaleukin Alfa (ALKS 4230) Monotherapy in Patients With Advanced Cutaneous Melanoma or Advanced Mucosal Melanoma - ARTISTRY-6 (ARTISTRY-6)

This study observes the antitumor activity, safety, tolerability, PK, and pharmacodynamics in patients with inoperable and/or metastatic melanoma following prior anti-PD-[L]-1 therapy

metastatic melanoma
malignant melanoma of skin
mucosal melanoma
pembrolizumab
cytotoxic t-lymphocyte antigen 4
  • 3 views
  • 04 Oct, 2022
  • 12 locations
Technology-Enabled Activation of Skin Cancer Screening for Stem Cell Transplant Survivors and Their Primary Care Providers, TEACH Study

This trial studies the impact of a 12-month invention focused on early detection of skin cancer and timely follow up in patients who underwent stem cell transplant and their primary care providers. Some stem cell transplant survivors may develop complications related to the treatment they received. Many of these complications …

skin cancer
allogeneic hematopoietic stem cell transplantation
cancer
  • 0 views
  • 04 Jun, 2022
  • 1 location
An Open-Label, Multicenter, Phase 1/2 Study of RP1 as a Single Agent and in Combination With PD1 Blockade in Patients With Solid Tumors (IGNYTE)

RPL-001-16 is a Phase 1/2, open label, dose escalation and expansion clinical study of RP1 alone and in combination with nivolumab in adult subjects with advanced and/or refractory solid tumors, to determine the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D), as well as to evaluate preliminary efficacy.

oximetry
progressive disease
measurable disease
malignant melanoma of skin
cancer
  • 127 views
  • 20 Sep, 2022
  • 46 locations
A Phase 1 Study of SGN-CD228A in Select Advanced Solid Tumors

This trial will study SGN-CD228A to find out whether it is an effective treatment for different kinds of cancer. It will also look at what side effects (unwanted effects) may occur. The study will have two parts. Part 1 of the study will find out how much SGN-CD228A should be …

progressive disease
metastatic cutaneous melanoma
measurable disease
pdac
lung cancer
  • 16 views
  • 19 Sep, 2022
  • 14 locations
MoleGazer Development Feasibility Study

Melanoma (skin cancer) frequently develops from existing moles on the skin. Current practice relies on expert dermatologists being able to successfully identify new/changing moles in individuals

cancer
skin cancer screening
  • 0 views
  • 30 Sep, 2021
  • 1 location
Gemini (Cancer Genetic Testing in Ethnic Populations)

This clinical trial examines the integration of cancer genetic testing in various ethnic populations. Studying individuals and families at risk of cancer may help identify cancer genes and other persons at risk. The information from this study may provide an opportunity for cancer risk stratification and individualized screening in these …

cancer
nervous
  • 0 views
  • 20 Sep, 2022
  • 2 locations
A Phase 1 Study of SEA-TGT (SGN-TGT) in Subjects With Advanced Malignancies

This trial will look at a drug called SEA-TGT (also known as SGN-TGT) to find out whether it is safe for patients with solid tumors and lymphomas. It will study SEA-TGT to find out what its side effects are. A side effect is anything the drug does besides treating cancer. …

salvage therapy
doxorubicin
b-cell lymphoma
lymphoma
pd-1 inhibitor
  • 110 views
  • 21 Sep, 2022
  • 33 locations
Molecular Analysis for Therapy Choice (MATCH)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

ipatasertib
gonadotropin releasing hormone
mammogram
antiretrovirals
erdafitinib
  • 6585 views
  • 14 Sep, 2022
  • 911 locations