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Found 4 clinical trials
Pyrexia Management Using an IL-6 Antibody in BRAF+ Melanoma Patients Treated With Dabrafenib/ Trametinib +/- Immunotherapy

blood pressure) due to cancer therapy (Tafinlar (dabrafenib) / Mekinist (trametinib) +/- immunotherapy) . The goal of the study is to better understand the side effects and to find an effective therapy

cancer
cytokines
persistent fever
  • 0 views
  • 13 Oct, 2021
  • 1 location
Study of Trametinib and Ruxolitinib in Colorectal Cancer and Pancreatic Adenocarcinoma

ruxolitinib are studied in combination. Trametinib is marketed in several countries with the brand name Mekinist® for the treatment of melanoma (a type of skin cancer). Trametinib has been studied extensively

tyrosine
gilbert's syndrome
neutrophil count
adenocarcinoma
liver metastasis
  • 11 views
  • 03 Jul, 2022
  • 1 location
Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy (PLGG - MEKTRIC)

lines and a better tumor response. Therefore, we designed a prospective open randomized phase II study, named PLGG-MEKTRIC, comparing the experimental arm (a daily MEK inhibitor, Trametinib, Mekinist©

  • 0 views
  • 28 Jul, 2022
  • 1 location
Observational Study for Melanoma Adjuvant Treatment With Tafinlar® + Mekinist® (Dabrafenib + Trametinib)

The primary objective for this non-interventional study is to assess the quality of life of melanoma patients under adjuvant treatment with dabrafenib and trametinib in real world setting in Portugal through disease specific FACT-M questionnaire and generic EQ-5D-3L questionnaire.The secondary study objectives are to assess the usage of adjuvant dabrafenib …

malignant melanoma of skin
immunologic adjuvant
dabrafenib
trametinib
  • 0 views
  • 29 Jun, 2022
  • 6 locations