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Found 59 clinical trials
Featured trial
ALTE07C1: Neuropsychological and Behavioral Testing in Young Patients with Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor (PNET)

ALTE07C1: Neuropsychological and Behavioral Testing in Young Patients with Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor (PNET)

  • 16 views
  • 08 Nov, 2020
  • 1 location
Featured trial
ACNS0332: Chemotherapy and Radiation Therapy in Treating Young Patients with Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma or Supratentorial Primitive Neuroectodermal Turn

ACNS0332: Chemotherapy and Radiation Therapy in Treating Young Patients with Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma or Supratentorial Primitive Neuroectodermal Turn

  • 127 views
  • 08 Nov, 2020
  • 1 location
Featured trial
ACNS0821:Temozolomide With Irinotecan Versus Temozolomide, Irinotecan Plus Bevacizumab (NSC# 704865, BB-IND# 7921) for Recurrent/Refractory Medulloblastoma/CNS PNET of Childhood, A COG Randomized Phase II Screening Trial

ACNS0821:Temozolomide With Irinotecan Versus Temozolomide, Irinotecan Plus Bevacizumab (NSC# 704865, BB-IND# 7921) for Recurrent/Refractory Medulloblastoma/CNS PNET of Childhood, A COG Randomized

  • 112 views
  • 08 Nov, 2020
  • 1 location
Featured trial
  • 364 views
  • 08 Nov, 2020
  • 1 location
A Phase I, Open-label, Parallel Group Study to Investigate Olaparib Safety and Tolerability, Efficacy and Pharmacokinetics in Paediatric Patients With Solid Tumours

A study to find out whether olaparib is safe and well tolerated when administered to children and adolescents with solid tumours.

  • 33 views
  • 25 Oct, 2022
  • 20 locations
  • 0 views
  • 24 Mar, 2022
  • 1 location
Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery

This is a multi center, Phase I, Phase II and surgical study of the CX-4945 drug (silmitasertib sodium) for patients with recurrent SHH (Sonic Hedgehog) medulloblastoma

  • 22 views
  • 07 Oct, 2022
  • 11 locations
Antiangiogenic Therapy for Children With Recurrent Medulloblastoma, Ependymoma and ATRT (MEMMAT)

Patients with relapsed medulloblastoma, ependymoma and ATRT have a very poor prognosis whether treated with conventional chemotherapy, high-dose chemotherapy with stem cell rescue, irradiation

karnofsky performance status
medulloblastoma
bevacizumab
combinations
ependymoma
  • 63 views
  • 07 Oct, 2022
  • 21 locations
A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma

Historically, medulloblastoma treatment has been determined by the amount of leftover disease present after surgery, also known as clinical risk (standard vs. high risk). Recent studies have

primitive neuroectodermal tumor
residual tumor
brain tumor
tumor cells
medulloblastoma
  • 144 views
  • 25 May, 2022
  • 1 location
A Phase 2 Study of Reduced Therapy for Newly Diagnosed Average-Risk WNT-Driven Medulloblastoma Patients

called WNT)/Wingless (WNT)-driven medulloblastoma. Recent studies using chemotherapy and radiation therapy have been shown to be effective in treating patients with WNT-driven medulloblastoma. However

MRI
residual tumor
medulloblastoma
neutrophil count
immunohistochemistry
  • 217 views
  • 14 Oct, 2022
  • 128 locations