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Found 63 clinical trials
Featured trial
ALTE07C1: Neuropsychological and Behavioral Testing in Young Patients with Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor (PNET)

ALTE07C1: Neuropsychological and Behavioral Testing in Young Patients with Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor (PNET)

  • 16 views
  • 08 Nov, 2020
  • 1 location
Featured trial
ACNS0332: Chemotherapy and Radiation Therapy in Treating Young Patients with Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma or Supratentorial Primitive Neuroectodermal Turn

ACNS0332: Chemotherapy and Radiation Therapy in Treating Young Patients with Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma or Supratentorial Primitive Neuroectodermal Turn

  • 127 views
  • 08 Nov, 2020
  • 1 location
Featured trial
ACNS0821:Temozolomide With Irinotecan Versus Temozolomide, Irinotecan Plus Bevacizumab (NSC# 704865, BB-IND# 7921) for Recurrent/Refractory Medulloblastoma/CNS PNET of Childhood, A COG Randomized Phase II Screening Trial

ACNS0821:Temozolomide With Irinotecan Versus Temozolomide, Irinotecan Plus Bevacizumab (NSC# 704865, BB-IND# 7921) for Recurrent/Refractory Medulloblastoma/CNS PNET of Childhood, A COG Randomized

  • 112 views
  • 08 Nov, 2020
  • 1 location
Featured trial
  • 361 views
  • 08 Nov, 2020
  • 1 location
Investigating Safety, Tolerability, Efficacy and PK of Olaparib in Paediatric Patients With Solid Tumours

A study to find out whether olaparib is safe and well tolerated when administered to children and adolescents with solid tumours.

  • 16 views
  • 14 May, 2022
  • 20 locations
177Lu-DTPA-Omburtamab Radioimmunotherapy for Recurrent or Refractory Medulloblastoma

Children and adolescents diagnosed with medullablastoma and with recurrent or refractory to frontline therapy will be treated with 177Lu-DTPA-omburtamab, which is a radioactive labelling of a murine monoclonal antibody targeting B7-H3.

  • 0 views
  • 10 Apr, 2022
  • 1 location
Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery

This is a multi center, Phase I, Phase II and surgical study of the CX-4945 drug (silmitasertib sodium) for patients with recurrent SHH (Sonic Hedgehog) medulloblastoma

  • 22 views
  • 22 Mar, 2022
  • 9 locations
  • 0 views
  • 24 Mar, 2022
  • 1 location
Antiangiogenic Therapy for Children With Recurrent Medulloblastoma, Ependymoma and ATRT (MEMMAT)

Patients with relapsed medulloblastoma, ependymoma and ATRT have a very poor prognosis whether treated with conventional chemotherapy, high-dose chemotherapy with stem cell rescue, irradiation

karnofsky performance status
ependymoma
combinations
medulloblastoma
bevacizumab
  • 63 views
  • 23 Apr, 2022
  • 20 locations
Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma

called WNT)/Wingless (WNT)-driven medulloblastoma. Recent studies using chemotherapy and radiation therapy have been shown to be effective in treating patients with WNT-driven medulloblastoma. However

MRI
cyclophosphamide
blood transfusion
seizure
residual tumor
  • 203 views
  • 09 Apr, 2022
  • 127 locations