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Found 63 clinical trials
Featured trial
ALTE07C1: Neuropsychological and Behavioral Testing in Young Patients with Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor (PNET)

ALTE07C1: Neuropsychological and Behavioral Testing in Young Patients with Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor (PNET)

  • 16 views
  • 08 Nov, 2020
  • 1 location
Featured trial
ACNS0332: Chemotherapy and Radiation Therapy in Treating Young Patients with Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma or Supratentorial Primitive Neuroectodermal Turn

ACNS0332: Chemotherapy and Radiation Therapy in Treating Young Patients with Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma or Supratentorial Primitive Neuroectodermal Turn

  • 127 views
  • 08 Nov, 2020
  • 1 location
Featured trial
ACNS0821:Temozolomide With Irinotecan Versus Temozolomide, Irinotecan Plus Bevacizumab (NSC# 704865, BB-IND# 7921) for Recurrent/Refractory Medulloblastoma/CNS PNET of Childhood, A COG Randomized Phase II Screening Trial

ACNS0821:Temozolomide With Irinotecan Versus Temozolomide, Irinotecan Plus Bevacizumab (NSC# 704865, BB-IND# 7921) for Recurrent/Refractory Medulloblastoma/CNS PNET of Childhood, A COG Randomized

  • 112 views
  • 08 Nov, 2020
  • 1 location
Featured trial
  • 364 views
  • 08 Nov, 2020
  • 1 location
A Phase I, Open-label, Parallel Group Study to Investigate Olaparib Safety and Tolerability, Efficacy and Pharmacokinetics in Paediatric Patients With Solid Tumours

A study to find out whether olaparib is safe and well tolerated when administered to children and adolescents with solid tumours.

  • 33 views
  • 20 Sep, 2022
  • 20 locations
PBTC-053: A Pediatric Brain Tumor Consortium Phase I/ II and Surgical Study of CX-4945 in Patients With Recurrent SHH Medulloblastoma

This is a multi center, Phase I, Phase II and surgical study of the CX-4945 drug (silmitasertib sodium) for patients with recurrent SHH (Sonic Hedgehog) medulloblastoma

  • 22 views
  • 16 Sep, 2022
  • 11 locations
  • 0 views
  • 24 Mar, 2022
  • 1 location
A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma

Historically, medulloblastoma treatment has been determined by the amount of leftover disease present after surgery, also known as clinical risk (standard vs. high risk). Recent studies have

tumor cells
residual tumor
craniospinal irradiation
primitive neuroectodermal tumor
brain tumor
  • 144 views
  • 25 May, 2022
  • 1 location
Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma

called WNT)/Wingless (WNT)-driven medulloblastoma. Recent studies using chemotherapy and radiation therapy have been shown to be effective in treating patients with WNT-driven medulloblastoma. However

tumor cells
blood transfusion
neutrophil count
medulloblastoma
cancer
  • 217 views
  • 11 Aug, 2022
  • 127 locations
A Phase II Study of Metronomic and Targeted Anti-angiogenesis Therapy for Children With Recurrent/Progressive Medulloblastoma, Ependymoma and ATRT (MEMMAT)

Patients with relapsed medulloblastoma, ependymoma and ATRT have a very poor prognosis whether treated with conventional chemotherapy, high-dose chemotherapy with stem cell rescue, irradiation

karnofsky performance status
combinations
ependymoma
bevacizumab
medulloblastoma
  • 63 views
  • 19 Sep, 2022
  • 21 locations