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Found 72 clinical trials
Evaluation of the Effect of Nabiximols Oromucosal Spray on Clinical Measures of Spasticity in Participants With Multiple Sclerosis (RELEASE MSS5)

This study will be conducted to evaluate the effect of multiple doses of nabiximols compared with placebo on a clinical measure of velocity-dependent muscle tone in the lower limbs (Lower Limb Muscle Tone-6 [LLMT-6]) in participants with multiple sclerosis (MS). LLMT-6 is defined as the average of the 6 individual …

  • 0 views
  • 04 Oct, 2022
  • 18 locations
Evaluating Buprenorphine/Naloxone Microdosing vs. Standard Dosing in Emergency Departments

This is a multi-centre, open-label RCT at four Emergency Departments (EDs) in British Columbia and Alberta. The purpose of the current study is to compare the effectiveness of buprenorphine/naloxone microdosing and standard dosing take-home induction regimens at enabling patients to successfully complete the induction regimen, and at retaining patients on …

  • 14 views
  • 10 Aug, 2021
  • 4 locations
Clinical Research of UCDA Reducing Medication Regimen in Stable PBC (UCDA PBC)

This study explores the feasibility of the reducing medication regimen for Ursodeoxycholic Acid(UDCA) in the treatment of primary biliary cholangitis. The participants will be distributed

  • 4 views
  • 10 May, 2022
  • 1 location
Unobtrusive Sensing of Medication Intake ("USE-MI") (USE-MI)

The purpose of this study is to test the USE-MI system hardware and software to see if it can accurately measure when subjects take their HIV-related medications and help them remember to take these medications. With the use of a smartwatch and smartphone "app", investigators hope to be able to …

  • 0 views
  • 16 May, 2022
  • 1 location
Cell Phone Support to Promote Medication Adherence Among Adolescents and Young Adults With Chronic Illness

Background: Adolescents and young adults (AYAs) with chronic illnesses often struggle to develop illness self-management skills. Mobile health (mHealth) interventions have been developed for some specific chronic illnesses, but flexible interventions that can be generalized across conditions are needed to accelerate translation. Research Hypotheses: 1) Cell phone support (CPS) will …

  • 0 views
  • 27 Mar, 2021
  • 1 location
A Virtual Intervention to Improve Medication Adherence in Pediatric Cancer: MedSupport

To develop a cancer center level practice intervention to promote treatment adherence and reduce outcome disparities in pediatric cancer survivors

Accepts healthy volunteers
  • 0 views
  • 24 Mar, 2022
  • 1 location
Life-Steps Counseling to Enhance Adherence and Engagement in PrEP Care

The purpose of this study is to test how different types of interventions may affect how someone takes their pre-exposure prophylaxis (PrEP) medication.

  • 0 views
  • 07 Oct, 2022
  • 1 location
A BCT Intervention for Medication Adherence Among Individuals on Statins

The purpose of this project is to identify the minimum effective dose (MED) of a multi-component behavioral change intervention required to increase levels of medication adherence among participants on primary prevention statin therapy who are at elevated risk for cardiovascular disease (CVD). The intervention will be comprised of 5 BCTs …

Accepts healthy volunteers
  • 0 views
  • 07 Oct, 2022
  • 1 location
Efficacy of Cranial Manual Therapy in the Treatment of Chronic Insomnia Disorder

Occupational Health, with characteristics of chronic insomnia described by the ICSD-III, who do not modify their usual medication regimen (if they take it) and without other pathologies related to sleep that

depression
sleep disorder
actigraphy
anxiety
chronic insomnia
  • 5 views
  • 13 Mar, 2022
  • 1 location
PRIME Care (PRecision Medicine In MEntal Health Care) 2.0

Background: In the last several years, commercial pharmacogenetic (PGx) testing for the selection of psychotropic medications has become widespread as a means of implementing "precision medicine", with some insurers electing to cover the cost of testing. Mostly these efforts have focused on the decision of choosing a medication. Polypharmacy has …

  • 0 views
  • 21 Jul, 2021
  • 1 location