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Found 290 clinical trials
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PATIENT INFORMATION SHEET AND CONSENT FORM (PIS/PIC) MOre REsponse on Cardiac Resynchronization Therapy (CRT) with MultiPoint Pacing (MPP) – CR-13-006-ID-HF More-CRT-MPP

Heart failure is the most rapidly growing cardiovascular condition in developed countries. Despite advances in medical therapy, patients with heart failure are at high risk for death and

defibrillation
  • 56 views
  • 24 Nov, 2020
  • 1 location
featured
TRISCEND II

Patients suffering from heart failure not responsive to optimal medical therapy and who are diagnosed with tricuspid valve insufficiency should be considered for this pivotal clinical trial.

  • 0 views
  • 27 Apr, 2021
  • 1 location
featured
A phase III randomized, double-blind trial to evaluate efficacy and safety of once daily empagliflozin 10 mg compared to placebo, in patients with chronic Heart Failure with reduced Ejection Fraction (HFrEF).

A phase III randomized, double-blind trial to evaluate efficacy and safety of once daily empagliflozin 10 mg compared to placebo, in patients with chronic Heart Failure with reduced Ejection Fraction (HFrEF).

  • 378 views
  • 25 Mar, 2021
  • 1 location
featured
Co-Infusion of Umbilical Cord Blood and Haploidentical CD34+ Cells Following Nonmyeloablative Conditioning as Treatment for Severe Aplastic Anemia and MDS Associated with Severe Neutropenia Refractory to Immunosuppressive Therapy

This study will evaluate the safety and effectiveness of treating patients with severe aplastic anemia (SAA) or myelopdysplastic syndrome (MDS) with both peripheral blood stem cells from a family member and umbilical cord blood stem cells from an unrelated donor. Patients with SAA or MDS for whom other treatments have …

myelodysplastic syndromes
myelodysplastic syndrome (mds)
anemia
aplastic anemia
anemia studies
  • 48 views
  • 22 Dec, 2020
  • 1 location
LTOT in COPD Patients With Moderate Chronic Hypoxemia and Chronic Heart Failure

medical therapy for both conditions can correct the moderate hypoxemia by improving the underlying mechanisms without the need of LTOT. If this hypothesis is correct, the study will provide a

pulmonary disease
medical therapy
COPD
  • 31 views
  • 07 Nov, 2020
  • 1 location
BioVentrix Revivent TC System Clinical Study

A prospective, multi-center, dual-arm pivotal study of the BioVentrix Revivent TC System, with 2:1 study vs. active concurrent control group allocation ratio. This study will include 126 patients of which 84 patients will be treated with the investigational device and 42 patients will be included in an active control group.

6-minute walk test
heart failure
ejection fraction
medical therapy
  • 44 views
  • 20 Mar, 2021
  • 37 locations
CCM in Heart Failure With Preserved Ejection Fraction

This pilot study will evaluate the efficacy and safety of CCM therapy in heart failure patients with baseline EF50% (HFpEF) who have New York Heart Association (NYHA) Class II or III symptoms despite appropriate medication. The terminology of the HF classification HFpEF is based on the 2016 European Society of …

medical therapy
crescendo
nt-probnp
heart failure with preserved ejection fraction
ejection fraction
  • 52 views
  • 06 May, 2021
  • 42 locations
A Collaborative Approach to Medication Reviews for Older Patients With Polypharmacy

In patients aged 65 years and older, polypathology is frequent and often associated with polypharmacy. This polypharmacy may be a source of iatrogeny due to pharmacokinetic interactions, enhanced sensitivity of older people to medication, or failure to adhere to the therapy. Since January 2018, French community pharmacists have been allowed …

  • 0 views
  • 26 Jan, 2021
  • 1 location
Revascularization Versus Optimal Medical Therapy of Chronic Total Coronary Occlusions on Left Ventricular Ischemia Reduction

Rationale: Randomized trials could not yet establish favourable outcomes of CTO PCI on hard endpoints such as ejection fraction or mortality, when compared to optimal medical therapy. However

  • 0 views
  • 24 Jan, 2021
  • 1 location
Efficacy of Medical Therapy in Women and Men With Angina and Myocardial Bridging

The proposed clinical trial is relevant to public health because it is expected to expand the differential diagnosis and provide an evidence--based therapy for the large population of patients with angina in the absence of obstructive CAD who currently remain undiagnosed and untreated. It, therefore, upholds an important part of …

  • 0 views
  • 26 Jan, 2021
  • 1 location