mechanical ventilation Clinical Research Trials

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Found 612 clinical trials

Study on the Effectiveness and Feasibility of Prone Position Ventilation Technology in Congenital Heart Disease

The purpose of this study was to compare the effects of conventional lying position and prone position ventilation on infants with acute lung injury after surgery for congenital heart disease. To explore the effectiveness and feasibility of prone position ventilation for children with acute lung injury after congenital heart disease …

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25 Jan, 2021
1 location

Obesity PEEP and Postoperative Oxygenation

A study on overweight patients undergoing anesthesia for laparoscopic surgery. evaluation of positive end-expiratory pressure versus zero positive end-expiratory pressure during awakening on oxygenation in the early postoperative period.

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24 Jan, 2021
3 locations

DISmantling COvid iNduced Neutrophil ExtraCellular Traps (DISCONNECT-1)

This is a pilot study to investigate the safety and feasibility of rhDNase1 and its impact on neutrophil extracellular traps (NETs) in COVID-19 infected patients.

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27 Jan, 2021
1 location

Comparison of Remdesivir Versus Lopinavir/ Ritonavir and Remdesivir Combination in COVID-19 Patients

Comparison outcomes of a large cohort of moderate and severe COVID-19 patients received remdesivir alone with patients who received remdesivir in combination with lopinavir/ ritonavir in addition to standard management.

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05 Mar, 2021
1 location

Treating Brain Swelling in Pediatric Cerebral Malaria

This study evaluates the effectiveness of two interventions in Malawian children with cerebral malaria at high risk of death. One-third of the participants will receive treatment as usual, one-third will receive treatment as usual and be placed on a mechanical ventilator, and one-third will receive treatment as usual plus intravenous …

5 views
23 Jan, 2021
1 location

LYT-100 in Post-acute COVID-19 Respiratory Disease

This study is a randomized, double-blind, parallel arm study to evaluate the safety and efficacy of LYT-100 compared to placebo in adults with post-acute COVID-19 respiratory complications

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04 Mar, 2021
10 locations

Prematurity Related Ventilatory Control (PRE-VENT) - Specific Aim 2

To determine if late (at or beyond postnatal day 14) mild permissive hypercapnia is associated with reduction in apnea, bradycardia, and hypoxemic episodes and with improved stability of oxygenation.

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24 Jan, 2021
1 location

Dexamethasone and the Prevention of Post-Extubation Airway Obstruction in Adults

Laryngotracheal injury related to intubation may cause narrowing of the airway due to edema of the glottis. Post-extubation airway frequently necessitating re-intubation and resulting in the prolongation of intensive care. Factors correlating with the development of post-extubation stridor include age, female gender, an elevated Acute Physiologic and Chronic Health Evaluation …

systolic blood pressure

pao2

intubation

oxygen saturation

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07 Nov, 2020
1 location

Effects of Dexmedetomidine vs Propofol in Patients With Intra-abdominal Sepsis

Sepsis is defined as systemic response to infection ,and it is a main problem in ICU and despite advance in supportive care, the mortality rate in patients with severe sepsis continues to exceed 30% [Bone RC 1993].The effects of bacterial invasion of body tissues result from combined actions of enzymes …

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30 Jan, 2021
1 location

Impact of Aromatherapy on the Delirium of Patients in Intensive Care Unit

The primary objective of this monocenter randomized controlled trial is to assess the efficacy of aromatherapy to prevent delirium in patients hospitalized in an intensive care unit.

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26 Jan, 2021
1 location

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Found 612 clinical trials