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Found 610 clinical trials
Combined Lung Ultrasounds and Transthoracic Electrical Bioimpedance in Preterm Infants With Respiratory Distress.

Respiratory distress syndrome (RDS) is among the most common complications of preterm birth, and typically becomes manifested soon after birth. A failure of the rapid reuptake of fetal lung fluids after birth, with subsequent liquid retention in the alveolar space, together with the deficit of surfactant proteins ensuing from lung …

  • 0 views
  • 25 Jan, 2021
  • 2 locations
Lung Ultrasound for COVID-19 Initial Triage and Monitoring

The QUICK study main aim is to assess the predictive value at Day 1, of a model built on lung ultrasound (LUS) and clinical data, both recorded at hospital admission of COVID-19 patients.

covid-19
  • 0 views
  • 25 Jan, 2021
  • 1 location
Systematic Assessment of SARS-CoV-2 Neurotropic Capacity in Modestly and Critically Ill Patients and Patients Who Died From COVID-19

This study is to analyze the microglia reaction or direct neurotropic effects of CNS COVID-19 in pathogenesis and brain stem dysfunction in critically ill patients. A microglia-focused, brain-specific 50+ marker CODEX panel is used to assess the neuroinflammatory microenvironment in specific brain regions of deceased COVID-19 patients. The peripheral (cerebrospinal …

  • 0 views
  • 28 Jan, 2021
  • 2 locations
Fiberoptic Bronchoscopy and Bronchoalveolar Lavage in Critically Ill Ventilated Patients

Fiberoptic bronchoscopy (FOB) is widely used as a diagnostic or therapeutic procedure in intensive care units. Patients with ARDS or COVID-19 disease often undergoes to these procedures. However, intensive care patients might suffer from serious side effects such as prolonged oxygen desaturation and adverse change in lung compliance and resistance. …

bronchoalveolar lavage
covid-19
acute respiratory distress syndrome
  • 0 views
  • 16 Feb, 2021
  • 1 location
Pediatric Intensive Care and COVID-19

In this prospective longitudinal cohort the investigators reported the clinical, and biological characteristics of all critically ill patients admitted in the pediatric intensive care unit (PICU) of Bictre Hospital during the 2019 coronavirus disease (COVID-19) pandemics. Patients were older than 37 weeks of gestational age. No upper limit was set …

  • 0 views
  • 26 Jan, 2021
  • 1 location
Baseline Vitamin D Deficiency and COVID-19 Disease Severity

It is known that vitamin D has been found to decrease incidence of viral respiratory infections, as well as have effects on multiple cytokines involved in immunomodulation and the bradykinin/renin-angiotensin system. Recently, data was released showing a correlation between baseline vitamin D deficiency status and increased risk of contracting COVID-19. …

  • 0 views
  • 26 Jan, 2021
  • 1 location
Natural History of Pompe Disease

The project is a prospective study in which patients affected by adult-onset Pompe disease with c.-32-13T>G mutation in the GAA gene will be followed-up during two years to describe the natural history using clinical, imaging, histological and molecular parameters. Secondary objectives are: To identify biomarkers for assessing efficacy of future …

walk test
gaa gene
  • 6 views
  • 19 Feb, 2021
  • 2 locations
Point of Care Ultrasound Measurements of Perioperative Edema in Infants With Congenital Heart Disease

Babies can be born with heart problems and sometimes need a heart surgery to fix the heart problem. Heart surgery can cause swelling from the build-up of extra fluid. Swelling can make it harder for babies to breath and has to be treated with medicine called diuretics. Swelling is hard …

congenital heart defects
heart surgery
edema
diuretics
cardiopulmonary bypass
  • 0 views
  • 24 Jan, 2021
  • 1 location
Continuous Exhaled Breath Condensate pH in Mechanically Ventilated Patients

Given the possible prognostic relationship between exhaled breath condensate pH and clinical symptoms, it is quite plausible that exhaled breath condensate pH can prove useful in the intensive care unit. For example, if exhaled breath condensate pH falls prior to the onset of clinical symptoms, it is likely that it …

extubation
pulmonary disease
pneumonia
ventilator associated pneumonia
  • 28 views
  • 07 Nov, 2020
  • 1 location
Esophagectomy Enhanced Recovery After Surgery Protocol

Despite the important advances in anaesthesia and the implementation of perioperative care, pulmonary complications in esophagectomy reach figures of between 20 and 35%, and these complications are also closely associated with the mortality rate. Factors that have been associated with the development of respiratory failure in the literature include among …

  • 0 views
  • 18 Feb, 2021
  • 1 location