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Found 615 clinical trials
Lowering PEEP: Weaning From High PEEP Setting

The perfusion of the deeply different areas coexisting in ARDS lung generates two type of venus-admixure : true shunt and shunt effect. Briefly, true shunt and shunt effect are related to non-aerated and poorly-ventilated lung areas perfusion respectively. Practically, it is not possible to quantify the true shunt and the …

positive end expiratory pressure
FIO2
pao2
  • 0 views
  • 26 Jan, 2021
  • 1 location
A Protocol Comparing Temporary Transvenous Diaphragm Pacing to Standard of Care for Weaning From Mechanical Ventilation

of care only) in patients aged 18 years or older who are receiving mechanical ventilation. Eligible Subjects will have received mechanical ventilation for 96 hours (4 days) and failed two weaning

  • 24 views
  • 25 Jan, 2021
  • 32 locations
Pharmacokinetics of Nebulized Amikacin in Patients With Pneumonia Undergoing Mechanical Ventilation

Inclusion of patients undergoing mechanical ventilation and presenting a pneumonia in order to determine serum pharmacokinetics of nebulized amikacin. The primary aim is to determine the

mechanical ventilation
  • 1 views
  • 07 Nov, 2020
  • 2 locations
A Study Evaluating Sedation of Intravenous Administration of HSK3486 Injectable Emulsion in ICU Patients Undergoing Mechanical Ventilation

This is a multi-center, randomized, single-blind, propofol-controlled phase III clinical study. In this study, ICU patients undergoing mechanical ventilation are expected to be enrolled and will

  • 0 views
  • 27 Jan, 2021
  • 1 location
Comparison of an Inhaled Sedation Strategy to an Intravenous Sedation Strategy in Intensive Care Unit Patients Treated With Invasive Mechanical Ventilation

The objective of the study is to determine the impact on the frequency of occurrence of delirium of an early inhaled sedation strategy (from induction in rapid sequence if intubation in intensive care, or from admission if intubated in pre -hospital) by Isoflurane using an ANACONDA type system, compared to …

  • 0 views
  • 27 Jan, 2021
  • 8 locations
Intravenous L-Citrulline to Delay and Potentially Prevent the Need for Invasive Mechanical Ventilation for Acute Hypoxemic Respiratory Failure in Patients With COVID-19 (SARS-CoV-2) Illness

Prospective, Randomized, Double-Blind, Placebo-Controlled Phase II Trial of Intravenous L-Citrulline (Turnobi) to Delay and Potentially Prevent the Need for Invasive Mechanical Ventilation for

  • 0 views
  • 27 Jan, 2021
  • 1 location
Early Mobilization in the ICU

To study all ICU patients with an independent baseline functional status , who experience a critical illness requiring intubation and mechanical ventilation evaluating long-term cognitive and

mechanical ventilation
intubation
assisted ventilation
critical illness
  • 15 views
  • 26 Jan, 2021
  • 1 location
CPAP in Liver Transplant

ventilation in patients who develop acute hypoxemia after liver transplant. Hypoxemia complicates the recovery of 30-50 % of patients after abdominal surgery; endotracheal intubation and mechanical

  • 4 views
  • 07 Nov, 2020
  • 1 location
Prone Position for Non-intubated Patients With Acute Respiratory Failure

The study will test the hypothesis that the prone position can be used to reduce the need for intubation and mechanical ventilation in patients with acute respiratory failure.

intubation
acute respiratory failure
mechanical ventilation
FIO2
pao2
  • 65 views
  • 07 Nov, 2020
  • 1 location
Study of M5049 in Participants With Coronavirus Disease 2019 (COVID-19) Pneumonia

The study will evaluate the safety and efficacy of orally-administered M5049 in COVID-19 pneumonia participants who are hospitalized but not on mechanical ventilation.

SARS
pneumonia
coronavirus infection
mechanical ventilation
FIO2
  • 92 views
  • 02 Feb, 2021
  • 17 locations