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Found 6 clinical trials
Effects of MDMA Co-administration on the Response to LSD in Healthy Subjects

similar substances for the treatment of depression. The 5-HT and oxytocin releaser 3,4-methylenedioxymethamphetamine (MDMA) reliably induces positive mood up to euphoria, comfort, empathy, and feelings of

  • 0 views
  • 04 Feb, 2021
  • 1 location
Open Label Multi-Site Study of Safety and Effects of MDMA-assisted Psychotherapy for Treatment of PTSD With Optional fMRI Sub-Study

This open-label, lead-in Phase 2 study is intended to gather supportive data on the safety and effectiveness of manualized MDMA-assisted psychotherapy as a treatment for PTSD. This will be the

mdma
suicidal
hypertension
functional magnetic resonance imaging
psychotherapy
  • 198 views
  • 11 Mar, 2021
  • 9 locations
The Effects of MDMA on Prefrontal and Amygdala Activation in PTSD.

This study aims to investigate the effects of MDMA on prefrontal and amygdala activation, and to explore the relationship between these MDMA-induced neural changes and the acute behavioral

mdma
  • 60 views
  • 12 Feb, 2021
  • 1 location
A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD

-blind, placebo-controlled, randomized Phase 3 study will assess the efficacy and safety of 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy compared to psychotherapy with placebo in

suicidal
mdma
psychotherapy
psychiatric disorder
  • 762 views
  • 11 May, 2021
  • 15 locations
MDMA in Subjects With Moderate Hepatic Impairment and Subjects With Normal Hepatic Function

This study is an open-label, single dose study evaluating the effect of moderate hepatic impairment in the pharmacokinetics of MDMA and its active metabolite, 3,4-methylene-dioxyamphetamine (MDA

alcohol test
moderate hepatic insufficiency
12 lead ECG
drugs of abuse
electrocardiogram
  • 1 views
  • 28 Feb, 2021
  • 1 location
Circulating Oxytocin Changes in Response to the Oxytocin System Stimulator MDMA in Patients With Diabetes Insipidus and Healthy Controls

This study is to evaluate oxytocin levels in response to MDMA administration as compared to placebo in patients with diabetes insipidus and healthy volunteers.

  • 0 views
  • 18 Feb, 2021
  • 1 location