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Found 518 clinical trials
Adjuvant Dendritic Cell Immunotherapy for Pediatric Patients With High-grade Glioma or Diffuse Intrinsic Pontine Glioma

Childhood aggressive gliomas are rare brain tumors with very poor prognosis. Due to the tumor's location and infiltrative nature, surgical removal is not always possible, and even when resection

  • 0 views
  • 28 Sep, 2021
  • 1 location
Tumor Hypoxia and Proliferation in Patients With High-Grade Glioma

This is a pilot study to assess a new methodology developed for High Grade Glioma (HGG). FMISO PET (Fluoromisonidazole-PET) allows researchers to study whether tumor cells lack oxygen (hypoxia

MRI
vegf
cancer
EGFR
vascular endothelial growth factor
  • 0 views
  • 15 Apr, 2021
  • 1 location
Personalized Vaccine for Patients With Recurrent Malignant Glioma

malignant glioma.

measurable disease
recurrent malignant glioma
malignant glioma
  • 0 views
  • 05 Jul, 2021
  • 1 location
MRI in High-Grade Glioma Patients Undergoing Chemoradiation

The purpose of this research study is to see if investigators can predict how brain functioning changes after radiation treatment based on PET scans and blood tests. Most participants experience at least mild decreases in their memory or attention after radiation therapy. Investigators hope that PET scans, lumbar puncture, and …

  • 0 views
  • 15 Jun, 2022
  • 1 location
D2C7 for Adult Patients With Recurrent Malignant Glioma

(CED) to recurrent World Health Organization (WHO) grade III and IV malignant glioma patients, and/or to determine what dose will be considered in a Phase II trial. Patients with recurrent WHO grade

neutrophil count
recurrent tumor
karnofsky performance status
brain mri
prothrombin
  • 162 views
  • 06 Apr, 2022
  • 1 location
Seizure Treatment in Glioma (STING)

Currently, treatment with a specific anti-epileptic drug mainly depends on the physicians' preference, as there are no studies supporting the use of one specific anticonvulsant in glioma

epilepsy
antiepileptic
oligodendroglioma, anaplastic
oligoastrocytoma
anticonvulsants
  • 9 views
  • 28 Feb, 2022
  • 4 locations
Talazoparib - Carboplatin for Recurrent High-grade Glioma With DDRd

In view of the strong biological rationale of employing PARP inhibition in high grade glioma, the current study purposes testing of talazoparib in a biomarker-enriched group of glioma

  • 0 views
  • 25 Aug, 2021
  • 1 location
Neoadjuvant Carilizumab and Apatinib for Recurrent High-Grade Glioma

glioma patients is still very poor. The study aim to Evaluate the Safety and efficiency of Using the neoadjuvant therapy with Carilizumab and Apatinib in patients with Recurrent High-Grade Glioma.

  • 0 views
  • 25 Jan, 2021
  • 1 location
A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade Glioma

any, these drugs have on children and young adults with brain tumors. The investigators are asking people to be in this research study who have been diagnosed with a high grade glioma (HGG

dipg
cancer
glioblastoma multiforme
platelet count
total resection
  • 1 views
  • 24 Mar, 2022
  • 9 locations
Anlotinib to Malignant Brainstem Glioma

This study is a single-arm, open-label, phase II study of anlotinib combined with radiation in the treatment of patients with malignant brainstem glioma. Twenty five patients will be enrolled in

  • 0 views
  • 26 Jan, 2021
  • 1 location