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Found 470 clinical trials
Effects of Intravenous Anesthesia and Balanced Anesthesia on Flash Visual Evoked Potentials

Intraoperative flash visual evoked potentials (FVEPs) could monitor visual function during neurosurgery. There are fewer reports comparing the effects of sevoflurane-propofol balanced anesthesia and propofol-based total intravenous anesthesia under comparable bispectral index (BIS) levels on the amplitude and latency of flash visual evoked potentials (FVEPs) for sellar or parasellar tumors …

  • 0 views
  • 13 Mar, 2021
  • 1 location
Safety and Feasibility of Preoperative and Intraoperative Image-Guided Resection of Gliomas

This study evaluates the use of specialized magnetic resonance imaging (MRI) techniques including magnetic resonance (MR) perfusion and 2-hydroxyglutarate (2HG) spectroscopy in the surgical treatment of gliomas. Participants will undergo an MR perfusion scan or 2-HG spectroscopy prior to surgery and intra-operatively.

  • 8 views
  • 26 Jan, 2021
  • 1 location
Novel Gamma-Delta ( )T Cell Therapy for Treatment of Patients With Newly Diagnosed Glioblastoma

This study is being conducted to find out if the safety and tolerability of an experimental cell therapy is safe to administer to patients with a newly diagnosed glioblastoma multiforme (GBM) in combination with temozolomide (TMZ).

  • 0 views
  • 01 May, 2021
  • 1 location
Brain Tumor-Specific Immune Cells (IL13Ralpha2-CAR T Cells) for the Treatment of Leptomeningeal Glioblastoma Ependymoma or Medulloblastoma

This phase I trial investigates the side effects of brain tumor-specific immune cells (IL13Ralpha2-CAR T cells) in treating patients with leptomeningeal disease from glioblastoma, ependymoma, or

  • 0 views
  • 03 Feb, 2021
  • 1 location
Rehabilitation and Longitudinal Follow-up of Cognition in Adult Lower Grade Gliomas

Patients with glial brain tumors have increasingly improved outcomes, with median survival of 5-15 years. However, the treatments, including surgery, radiation, and chemotherapy, often lead to

seizure
brain tumor
MRI Scan
stroke
karnofsky performance status
  • 0 views
  • 25 Jan, 2021
  • 1 location
Feasibility of 11C-MET PET/MRI Imaging in Pediatric Brain Fossa Tumors

. To the best of our knowledge, there is no specific study on primary brain tumors of the posterior fossa in children using 11C-MET PET/MRI. The primary objectives of this first pilot study is

  • 0 views
  • 26 Jan, 2021
  • 2 locations
Hypofractionated Stereotactic Radiotherapy in Recurrent Glioblastoma Multiforme

Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults. The treatment comprises maximal safe resection followed by radiotherapy and chemotherapy. Despite appropriate

  • 15 views
  • 23 Jan, 2021
  • 1 location
Intracavitary Carrier-embedded Cs131 Brachytherapy for Recurrent Brain Metastases: a Randomized Phase II Study

The purpose of this study is to see if Cs-131 brachytherapy is effective in people with recurrent brain cancer who are scheduled to have brain surgery for removal of their tumor(s). The

  • 0 views
  • 16 May, 2021
  • 5 locations
A Single Arm Study of Brain Metastasis in Patients With HER2-positive Breast Cancer

The aim of this study was to evaluate the progression time and efficacy of brain tumors in patients with brain metastases from HER2-positive breast cancer treated with Pyrrolidine and

  • 0 views
  • 03 Mar, 2021
  • 1 location
Awake vs. Asleep Craniotomy for Non-eloquent Gliomas

This study protocol examines a comparison between local and general anesthesia (Awake vs. Asleep Craniotomy) in the removal of brain tumors that are in areas of the brain that do not directly

  • 0 views
  • 25 Jan, 2021
  • 1 location