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Found 68 clinical trials
GD2/CD56 Bi-specific CAR-T Cell Therapy

The purpose of this clinical trial is to assess the feasibility, safety and efficacy of anti-GD2/CD56 bi-specific CAR-T cell therapy in patients with GD2 and/or CD56 positive cancer. Another goal of the study is to learn more about the function of the anti-GD2/CD56 bi-specific CAR-T cells and their persistency in …

  • 14 Jul, 2022
  • 1 location
Using T-Cell Alloreactivity and Chimerism to Guide Immunosuppression Minimization in Intestinal Transplantation

their organ donor's bone marrow. The goal of this is to develop a post-transplant treatment strategy that controls rejection while reducing the high risk of infection and malignant disease associated

  • 05 Jan, 2022
Digital Lifestyle Management for Weight Loss Control After Thyroidectomy in Thyroid Cancer Patients

many potential health problems, such as heart disease, diabetes, high blood pressure, and malignant disease. Recently, digital health care technology has been developed and applied for medical

  • 25 Nov, 2021
  • 1 location
Omega-3 and Vitamin D Supplementation in Breast Cancer Women

Breast cancer (BC) is the most common malignant disease, which is fifth leading cause of cancer mortality worldwide. Poor nutritional status is one of the common physical symptoms found among

  • 26 May, 2022
Trial on Intraoperative Neuromonitoring (IONM) in Thyroid Cancer Surgery. (ACTION)

Scientific objectives: Primary objective: • To assess if the use of IONM can decrease the rates of temporary RLN palsy after thyroid cancer surgery Secondary objectives: To assess if the use of IONM can decrease permanent RLN palsy rates in patients with thyroid cancers To assess voice parameters in patients …

  • 09 May, 2022
  • 1 location
PAlliative RAdioTherapy to Lung Cancer A Randomized Multicentre Phase III Study (PARAT)

The aim of this study is to examine if a shorter palliative radiotherapy fractionation scheme of 20 Gy / 4 F can reduce the early oesophageal toxicity compared to 30 Gy / 10 F in patients with lung cancer in performance status (PS) 0-2. Secondary aims are to examine the …

lung carcinoma
lung cancer
  • 05 Jun, 2022
  • 1 location
The Role of Stereo-tActic BoDy RadIotherApy iN Oligo-Progressive MalignanT Disease (RADIANT)

Systemic therapy is the main treatment for patients with metastatic cancers. Oligo-progression has become a recognized entity for metastatic cancer and it is thought that a subset of cancer cells may develop heterogeneity and resistant clones while receiving systemic therapy. This results in overall tumor response but progression in metastatic …

primary cancer
breast cancer
  • 24 Oct, 2022
  • 1 location
A Prospective, Multi-Center Investigation of the da Vinci SP Surgical System in Pulmonary and Lobectomy for Benign and Malignant Disease

To confirm the safety and performance of the da Vinci SP Surgical System, Instruments and Accessories in pulmonary lobectomy, and in thymectomy procedures.

  • 13 Oct, 2022
  • 1 location
Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders

This study is designed to estimate the efficacy and toxicity of familial HLA mismatched bone marrow transplants in patients with non-malignant disease who are less than 21 years of age and could

reduced intensity conditioning
mycophenolate mofetil
pulse oximetry
  • 07 Mar, 2022
  • 2 locations
CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant

peripheral blood stem cell transplant in order to decrease the risk of acute and chronic GVHD. This study involves subjects who are diagnosed with a malignant disease, that has either failed standard

blood stem cell transplant
blast crisis
blast cells
lymphoid leukemia
  • 01 Nov, 2021
  • 1 location