Found 17496 clinical trials
Study of Combination Therapy With INCMGA00012 (Anti-PD-1), INCAGN02385 (Anti-LAG-3), and INCAGN02390 (Anti-TIM-3) in Participants With Select Advanced Malignancies
The study will determine Recommended Phase 2 Dose for all study drugs, based on the safety and tolerability of the following combinations: INCAGN02385 + INCAGN02390 and INCAGN02385 + INCAGN02390 + INCMGA00012.
- 2 views
- 10 May, 2022
- 2 locations
A Randomized, Double-blind, Placebo Controlled Phase III Study of ODM-201 Versus Placebo in Addition to Standard Androgen Deprivation Therapy and Docetaxel in Patients With Metastatic Hormone Sensitive Prostate Cancer. NCT02799602, Bayer 1777.
metastatic hormone sensitive prostate cancer.
- 109 views
- 02 Sep, 2021
- 1 location
A Multi-Center, Randomized, Assessor-Blind, Controlled Trial Comparing the Occurrence of Major Adverse Cardiovascular Events (MACEs) in Patients With Prostate Cancer and Cardiovascular Disease Receiving Degarelix (Gonadotropin-Releasing Hormone (GnRH) Receptor Antagonist) or Leuprolide (GnRH Receptor Agonist) NCT02663908, Ferring 000108.
The purpose of this trial is to test if a marketed drug for advanced prostate cancer (FIRMAGON) can reduce the risk of cardiovascular complications as compared to another marketed drug for
- 127 views
- 02 Sep, 2021
- 1 location
ATLAS: A Randomized, Double-blind, Placebo-controlled Phase 3 Study of JNJ-56021927 in Subjects With High-risk, Localized or Locally Advanced Prostate Cancer Receiving Treatment With Primary Radiation Therapy. NCT02531516, PCR3003.
The purpose of this study is to determine if apalutamide plus gonadotropin releasing hormone (GnRH) agonist in participants with high-risk, localized or locally advanced prostate cancer receiving
- 60 views
- 02 Sep, 2021
- 1 location
BLOOD SAMPLE COLLECTION- UNTREATED MELANOMA
MELANOMA, ALSO KNOWN AS MALIGNANT MELANOMA, IS A TYPE OF CANCER THAT DEVELOPS FROM THE PIGMENT-CONTAINING CELLS KNOWN AS MELANOCYTESUP OF FAT IN THE LIVER.
- 88 views
- 03 Oct, 2019
- 1 location
Healthy Male Research Study
Looking for males 18-65 years of age, non-smokers, no drug or alcohol in take within past 30 years, no history of cancer, hep, hiv, high cholesterol or high blood pressure. Restrictions apply.
- 557 views
- 23 Nov, 2020
- 1 location
Response to the SHINGRIX Varicella Zoster Virus (VZV) Vaccine in Chronic Lymphocytic Leukemia (CLL) Patients that are Treatment Naive or Receiving Bruton s-Tyrosine Kinase Inhibitor (BTK-I) Therapy
Background: People who have cancer tend to get sick more often. This is in part because of the cancer treatments they get. Because of this, they may get shingles
- 228 views
- 09 Apr, 2019
- 1 location
Ibrutinib, Fludarabine, and Pembrolizumab in High-Risk or Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Background: Chronic lymphocytic leukemia (CLL) is a cancer of white blood cells. It is also called small lymphocytic lymphoma (SLL). It causes tiredness, night sweats
- 348 views
- 23 Nov, 2020
- 1 location
Natural History Study of Monoclonal B Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma(CLL/SLL), Lymphoplasmacytic Lymphoma(LPL)/Waldenstrom Macroglobulinemia (WM), and Splenic Marginal Zone Lymphoma(SMZL)
, but patients may be asked to undergo these procedures for research purposes) Clinical information is collected and stored in a central databank. Patients whose cancer requires
- 115 views
- 15 Apr, 2019
- 1 location
A Pilot Phase II Study Using Ibrutinib and Short-Course Fludarabine in Previously Untreated Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)
Background: Chronic lymphocytic leukemia (CLL) and/or small lymphocytic lymphoma (SLL) are tumors of abnormal B cells that often affect elderly patients. Studies have
- 169 views
- 15 Apr, 2019
- 1 location