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Found 17166 clinical trials
Featured trial
A Study Exploring the Safety and Tolerability of INCB081776 in Participants With Advanced Malignancies

The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics, pharmacodynamics, and early clinical activity of single-agent INCB081776 (Part 1) and INCB081776 in combination with INCMGA00012 (Part 2).

  • 0 views
  • 08 Jul, 2022
  • 11 locations
Featured trial
  • 380 views
  • 11 Aug, 2022
  • 150 locations
Featured trial
Study of Combination Therapy With INCMGA00012 (Anti-PD-1), INCAGN02385 (Anti-LAG-3), and INCAGN02390 (Anti-TIM-3) in Participants With Select Advanced Malignancies

The study will determine Recommended Phase 2 Dose for all study drugs, based on the safety and tolerability of the following combinations: INCAGN02385 + INCAGN02390 and INCAGN02385 + INCAGN02390 + INCMGA00012.

pd-1 inhibitor
BRAF
immunologic adjuvant
  • 0 views
  • 20 Jul, 2022
  • 5 locations
Featured trial
Feasibility of a Systems Approach for Alzheimer's Services Among Latinos Attending Primary Care Practices

The research team will train primary care practitioners from Kansas City clinics to enhance skills in cultural competence, dementia detection, treatment and referral to a Health Navigator among Latinos 65 and older with dementia. The Health Navigator will provide patient/caregiver dyads referred by Alianza Latina providers with care management, psychosocial …

cognitive impairment
mild cognitive impairment
  • 0 views
  • 13 Jul, 2022
  • 1 location
Featured trial
INCB106385 Alone or in Combination With Immunotherapy in Advanced Solid Tumors

of INCB106385 when given as monotherapy or in combination with INCMGA00012 in participants with selected CD8 T-cell-positive advanced solid tumors including SCCHN, NSCLC, ovarian cancer, CRPC, TNBC

cancer
cancer of the ovary
measurable disease
bladder tumor
  • 17 views
  • 11 Jul, 2022
  • 19 locations
Featured trial
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid Tumors

The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics, pharmacodynamics, and early clinical activity of INCB099280 in participants with select solid tumors

  • 0 views
  • 19 Jun, 2022
  • 16 locations
Featured trial
  • 0 views
  • 11 Jul, 2022
  • 19 locations
Featured trial
Safety and Efficacy of Retifanlimab (INCMGA00012) Alone or in Combination With Other Therapies in Participants With Advanced or Metastatic Endometrial Cancer Who Have Progressed on or After Platinum-based Chemotherapy. (POD1UM-204)

This is a multicenter, open-label, nonrandomized, Phase 2 umbrella study of retifanlimab in participants who have advanced or metastatic endometrial cancer that has progressed on or after

cancer
platinum-based chemotherapy
metastatic endometrial cancer
  • 8 views
  • 22 Jul, 2022
  • 52 locations
Featured trial
  • 0 views
  • 11 Aug, 2022
  • 120 locations
Featured trial
A Study Evaluating Safety and Tolerability and Pharmacokinetics of Navitoclax Monotherapy and in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasm

neoplasm (MPN) or chronic myelomonocytic leukemia (CMML).

chronic myelomonocytic leukemia
bone marrow procedure
polycythemia
polycythemia vera
leukemia
  • 49 views
  • 23 Jul, 2022
  • 36 locations