Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 43 clinical trials
None
Concurrent fMRI-guided rTMS and Cognitive Therapy for the Treatment of Major Depressive Episodes

Background Repetitive transcranial magnetic stimulation (rTMS) is a treatment for depression. It stimulates the brain. Researchers want to see if using magnetic resonance imaging (MRI) scans helps locate the best area for rTMS in each person. They also want to find other ways to make it more effective. Objective To …

cognitive therapy
MRI
major depressive disorder
major depressive disorder, single episode
antidepressants
  • 115 views
  • 13 Nov, 2021
  • 1 location
None
Antidepressant Trial With P2X7 Antagonist JNJ-54175446

Depression is one of the most important causes of disability in the world today, with major personal, social and economic costs. Although some moderately effective drug treatments are already available, about a third of patients with major depressive disorder (MDD) remain depressed despite current treatment. There is growing evidence that …

12 lead ECG
electrocardiogram
depressed mood
depression
  • 24 views
  • 06 Aug, 2021
  • 5 locations
None
Digital Game: A Scale to Evaluate the Perioperative Cognitive Function

INTRODUCTION: Cognitive dysfunction is a frequent adverse event in the postoperative period, especially in elderly patients. The tests commonly used for the detection of postoperative cognitive dysfunction are time-consuming and with variable sensitivity and specificity and difficult routine use. Applying a difficult battery of cognitive tests decreases the viability of …

cancer
diabetes
hypertension
cognitive impairment
postoperative cognitive dysfunction
  • 0 views
  • 24 Jan, 2021
  • 1 location
None
Effects of the Transcranial Stimulation on Prevention of Cognitive Dysfunction in Cardiac Surgery

Postoperative cognitive dysfunction (POCD) is a contrary event observed between 20 to 83%, especially on elderly and patients submitted to cardiac surgery. The prevention and rehabilitation on cases of POCD can improve the quality of life and decrease the mortality in surgical patients. The effect of the noninvasive cerebral stimulation, …

brain injury
cognitive impairment
heart surgery
depression
  • 12 views
  • 25 Jan, 2021
  • 1 location
None
A Pilot Study of Creatine Monohydrate as an Augmenting Agent for ECT in Persons With Major Depressive Disorder

We propose to determine if augmentation of electroconvulsive therapy (ECT) utilized for the treatment of major depressive disorder (MDD) with daily oral creatine will lead to an accelerated response to treatment, an overall increase in response rate, and will protect against cognitive adverse effects associated with ECT. We propose to …

depression
creatine monohydrate
electroconvulsive therapy
major depressive disorder
  • 0 views
  • 05 Nov, 2021
  • 1 location
None
University of Iowa Interventional Psychiatry Service Patient Registry

The purpose of this study is to examine the effects of interventional/procedural therapies for treatment-resistant depression (TRD). These treatments include electroconvulsive therapy (ECT), transcranial magnetic stimulation (TMS), racemic ketamine infusion and intranasal esketamine insufflation. The investigators will obtain various indicators, or biomarkers, of a depressed individuals' state before, during, and/or …

depressive disorder
bipolar disorder
depressed
ketamine
major depressive disorder, single episode
  • 0 views
  • 18 Apr, 2021
  • 1 location
None
Depressive Symptoms and Subjective Stress in the Course of the Menstrual Cycle - an Ambulatory Assessment Study.

Background Major changes in female sex hormone concentrations influence the development of depressive symptoms in women. This hypothesis has been thoroughly investigated with regard to the menopause, the postpartal phase and also premenstrual dysphoric disorder. However, much less is known regarding the impact of female sex hormone fluctuations on depression …

  • 44 views
  • 01 Oct, 2021
  • 2 locations
None
Assessement of Capacity to Consent

Any patient can request euthanasia in many of our neighbouring European countries as long as informed consent is given. Psychiatric evaluation is not always mandatory. Faced with the increasing emergence of euthanasia requests in different countries from patients under psychiatric care in France for severe depressive episodes, question arises of …

  • 0 views
  • 26 May, 2021
  • 1 location
None
Neuroinflammation in COVID-19 and Depression

The purpose of this study is to use state of the art brain imaging technology to investigate neuroinflammation in participants with depression after the respiratory symptoms of COVID-19 have passed.

  • 0 views
  • 01 May, 2021
  • 1 location
None
The Effects of Anger and Joy Expressions on Approach and Avoidance Behaviors in Healthy Volunteers

Social interactions are part of our daily lives. Communicating with others is a recurring choice which is based on emotional cues, such as facial expression. Our action must be adapted to the emotional state of our interlocutor, otherwise the investigators will have poor quality interactions An emotional stimulus would cause …

  • 75 views
  • 18 Sep, 2021
  • 1 location