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Found 461 clinical trials
Definitive Selection of Neuroimaging Biomarkers for the Diagnosis and Treatment to Common Mental Disorders

To explore the whole-brain anatomical and functional abnormalities in drug-naive patients with schizophrenia ,drug-naive patients with BD, drug-naive patients with MDD and healthy controls by

  • 0 views
  • 25 Jan, 2021
  • 1 location
Feasibility of Adherence to Light Therapy

In this feasibility study, we propose an important question: What factors will affect participant adherence to the daily use of light therapy for maintenance treatment of depression? To answer this question, we will conduct a pilot study of open-label treatment with light therapy in a small sample (n=10) of participants …

  • 0 views
  • 06 Oct, 2021
  • 1 location
Optimal Dose of a Cognitive Control Training for Depression Vulnerability

This study aims to examine the dose-response relationship of an online adaptive cognitive control training on depressive symptomatology and rumination. Participants will be randomized over six groups, each receiving a different dose (0, 1, 5, 10, 15 or 20 sessions) of a cognitive control training in remitted depressed patients. An …

Accepts healthy volunteers
  • 0 views
  • 14 Apr, 2022
  • 1 location
Minocycline as Adjunctive Treatment for Treatment Resistant Depression (MINDEP2)

Major depressive disorder (MDD) is a leading cause of disability worldwide. Up to 50% of patients experience treatment resistant depression (TRD), which accounts for a vast majority of disease

antidepressants
psychosis
depressive symptoms
adjunctive treatment
mirtazapine
  • 110 views
  • 25 May, 2022
  • 1 location
Exploring the Cortical Hemodynamic Response of Excitatory Brain Stimulation: a Pilot Study

Intermittent theta-burst stimulation (iTBS) is a promising treatment for major depressive disorder. However, fewer than 50% of patients show sufficient response. Therefore, the optimal treatment

Accepts healthy volunteers
  • 0 views
  • 12 Aug, 2022
  • 1 location
Evaluation of tDCS Efficacy in Enduring Anorexia Nervosa

patients. tDCS (transcranial direct current stimulation) is a non-invasive stimulation technique that has demonstrated beneficial effects in other psychiatric conditions such as major depression or

  • 5 views
  • 07 Aug, 2021
  • 4 locations
Enhanced Spatial Targeting in ECT Utilizing FEAST

patients suffering from Major Depressive Disorder by minimizing side effects and maintaining or improving efficacy.

  • 0 views
  • 06 Jun, 2022
  • 1 location
Neuromodulation for Dysphoria

major depressive disorder. Accelerated TMS is the delivery of treatment in a shorter period of time. The primary objective of this study to demonstrate the preliminary effectiveness

  • 0 views
  • 10 Dec, 2021
  • 1 location
Tianeptine for Treatment Resistant Depression

of this program and holds the IND for tianeptine use in this study. Investigators will recruit 75 participants with current unipolar MDD, non-delusional, between 21-50, who have failed at

antidepressants
depressive disorder
bupropion
snri
mirtazapine
  • 41 views
  • 21 Apr, 2022
Neurofeedback for Treatment Resistant Depression

The purpose of this study is to determine the clinical efficacy of real-time functional magnetic resonance imaging neurofeedback (rtfMRI-nf) training to increase the amygdala's response to positive autobiographical memories in patients with depression who are considered treatment-resistant

antidepressants
anhedonia
depressed
functional magnetic resonance imaging
  • 216 views
  • 24 Mar, 2022
  • 1 location