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Found 503 clinical trials
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Adolescent Non-Drug Depression Study: A randomized, sham-controlled trial Evaluating the Safety and Effectiveness of ---- device in depressed adolescents

Adolescent Non-Drug Depression Study: A randomized, sham-controlled trial Evaluating the Safety and Effectiveness of ---- device in depressed adolescents

  • 344 views
  • 23 Nov, 2020
  • 1 location
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A Placebo-controlled, Double-blind, Parallel-group, Bayesian Adaptive Randomization Design and Dose Regimen-finding Study to Evaluate Safety, Tolerability and Efficacy of BAN2401 in Subjects With Early Alzheimer's Disease

A Placebo-controlled, Double-blind, Parallel-group, Bayesian Adaptive Randomization Design and Dose Regimen-finding Study to Evaluate Safety, Tolerability and Efficacy of BAN2401 in Subjects With Early Alzheimer's Disease

  • 146 views
  • 08 Dec, 2020
  • 1 location
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A 26-Week, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Investigate the Effects of Daily Administration of AC-1204 in Participants With Mild to Moderate Alzheimer's Disease (AD) With an Optional 26-Week Open Label Extension

A 26-Week, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Investigate the Effects of Daily Administration of AC-1204 in Participants With Mild to Moderate Alzheimer's Disease (AD) With an Optional 26-Week Open Label Extension

  • 106 views
  • 08 Dec, 2020
  • 1 location
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A Phase 2a, Randomized, Placebo-Controlled Clinical Study to Evaluate the Efficacy and Safety of MK-1942 Added to Stable Antidepressant Therapy in Participants With Treatment-Resistant Depression

Merck Sharp & Dohme Corp. is conducting this trial to test the investigational drug MK-1942 in people with treatment-resistant depression. The purpose of this trial is to test the safety, efficacy, and tolerability of the trial drug, MK-1942.Additionally, the sponsor is interested to see if subjects who get MK-1942 have …

  • 0 views
  • 06 Apr, 2021
  • 1 location
Comparative Effectiveness Research Trial for Antidepressant Incomplete and Non-responders With TRD

This is a multi-site, randomized, open-label, effectiveness trial comparing three treatment arms for Major Depressive Disorder (MDD) patients with TRD who are currently on ongoing, stable and

  • 800 views
  • 25 Jan, 2021
  • 22 locations
A Study of JNJ-61393215 in the Treatment of Depression

Hamilton Depression Rating Scale (HDRS-17) in participants with major depressive disorder (MDD) with anxious distress with a score greater than or equal to (>=) 2 on item 26 or 27 of the Inventory of

  • 277 views
  • 01 Sep, 2021
  • 50 locations
Building Infrastructure for Community Capacity in Accelerating Integrated Care

Although the Affordable Care Act (ACA) expanded Medicaid eligibility, Medicaid expansions do not appear to have decreased the gap in mental health treatment between Whites and racial/ethnic or linguistic minorities. There is a critical shortage of trained providers who can offer culturally congruent mental health service in non-English languages in …

  • 0 views
  • 04 Mar, 2021
  • 2 locations
Efficacy and Safety of Psilocybin in Treatment-Resistant Major Depression

The study aims to investigate the safety and efficacy of oral psilocybin administered under supportive conditions in treatment-resistant major depression (TRD). The study is a bi-centric

  • 0 views
  • 08 Aug, 2021
  • 2 locations
A Naturalistic Study of the Efficacy and Safety of Escitalopram in Treatment Resistant Depression

The primary objective of this multicenter study is to evaluate the efficacy of escitalopram in treatment resistant depression (TRD), assessed by 2 consecutive failed antidepressant treatments from different classes. The last treatment received is a 6 week prospective trial with venlafaxine.

major depressive disorder
antidepressants
depression
citalopram
venlafaxine
  • 24 views
  • 07 Nov, 2020
  • 2 locations
Cognitive Behavioral Therapy Following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention

This is a rater-blinded, randomized controlled trial. All patients will receive esketamine for treatment of Major Depression with Suicidal Ideation (MDSI). Subjects will be randomized (1:1) to

  • 0 views
  • 18 Mar, 2021
  • 1 location